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pro vyhledávání: '"Chen-Ming Fan"'
Autor:
Federico Sizzano, Reinhard Fässler, Liangji Li, Nicolas A. Dumont, Umji Lee, Michelle Rozo, Eugenia Migliavacca, Manuel Schmidt, Frederic Raymond, Pascal Steiner, Laura Lukjanenko, Jerome N. Feige, Claire Perruisseau-Carrier, Michael A. Rudnicki, David H. Wilson, M Juliane Jung, Patrick Descombes, Julia von Maltzahn, Sylviane Metairon, Guillaume Jacot, Sonia Karaz, Nagabhooshan Hegde, Chen-Ming Fan, Alessio Palini, C. Florian Bentzinger
Publikováno v:
Nature Medicine
Age-related changes in the niche have long been postulated to impair the function of somatic stem cells. Here we demonstrate that the aged stem cell niche in skeletal muscle contains substantially reduced levels of fibronectin (FN), leading to detrim
Publikováno v:
Nature medicine
Interactions between stem cells and their microenvironment, or niche, are essential for stem cell maintenance and function. Our knowledge of the niche for the skeletal muscle stem cell, i.e., the satellite cell (SC), is incomplete. Here we show that