Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shah SH"'
Autor:
Schormair B; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany. barbara.schormair@helmholtz-munich.de.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany. barbara.schormair@helmholtz-munich.de., Zhao C; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Bell S; Department of Oncology, University of Cambridge, Cambridge, UK.; Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.; Cancer Research UK Cambridge Institute, Li Ka Shing Centre, University of Cambridge, Cambridge, UK., Didriksen M; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Neuroscience, University of Copenhagen, Copenhagen, Denmark., Nawaz MS; deCODE Genetics/Amgen, Reykjavik, Iceland., Schandra N; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Stefani A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Högl B; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Dauvilliers Y; Sleep-Wake Disorders Center, Department of Neurology, Hôpital Gui-de-Chauliac, CHU Montpellier, Institut des Neurosciences de Montpellier, INSERM, Université de Montpellier, Montpellier, France., Bachmann CG; SomnoDiagnostics, Osnabrück, Germany.; Department of Neurology, University Medical Center Göttingen, Göttingen, Germany., Kemlink D; Department of Neurology and Centre of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Sonka K; Department of Neurology and Centre of Clinical Neuroscience, Charles University, First Faculty of Medicine and General University Hospital, Prague, Czech Republic., Paulus W; Department of Neurology, Ludwig Maximilians University Munich, Munich, Germany., Trenkwalder C; Paracelsus-Elena-Klinik, Kassel, Germany.; Department of Neurosurgery, University Medical Center Göttingen, Göttingen, Germany., Oertel WH; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Department of Neurology, Philipps-University Marburg, Marburg, Germany., Hornyak M; Neuropsychiatry Centre Erding/München, Erding, Germany., Teder-Laving M; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Metspalu A; Estonian Genome Center, Institute of Genomics, University of Tartu, Tartu, Estonia., Hadjigeorgiou GM; Department of Neurology, Nicosia General Hospital Medical School, University of Cyprus, Nicosia, Cyprus., Polo O; Bragée ME/CFS Center, Stockholm, Sweden., Fietze I; Department of Pulmonology, Center of Sleep Medicine, Charité-Universitätsmedizin Berlin, Berlin, Germany., Ross OA; Department of Neuroscience, Mayo Clinic College of Medicine, Jacksonville, FL, USA., Wszolek ZK; Department of Neurology, Mayo Clinic, Jacksonville, FL, USA., Ibrahim A; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Bergmann M; Sleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria., Kittke V; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Harrer P; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany., Dowsett J; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Chenini S; Sleep-Wake Disorders Center, Department of Neurology, Hôpital Gui-de-Chauliac, CHU Montpellier, Institut des Neurosciences de Montpellier, INSERM, Université de Montpellier, Montpellier, France., Ostrowski SR; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark., Sørensen E; Department of Clinical Immunology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Erikstrup C; Department of Clinical Immunology, Aarhus University Hospital, Aarhus, Denmark.; Department of Clinical Medicine, Aarhus University, Aarhus, Denmark., Pedersen OB; Department of Clinical Medicine, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Immunology, Zealand University Hospital, Køge, Denmark., Topholm Bruun M; Department of Clinical Immunology, Odense University Hospital, Odense, Denmark., Nielsen KR; Department of Clinical Immunology, Aalborg University Hospital, Aalborg, Denmark., Butterworth AS; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK., Soranzo N; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Department of Haematology, University of Cambridge, Cambridge, UK.; Department of Human Genetics, the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Ouwehand WH; Department of Haematology, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant, Cambridge Biomedical Campus, Cambridge, UK.; Department of Haematology, University College London Hospitals, London, UK., Roberts DJ; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Radcliffe Department of Medicine and National Health Service Blood and Transplant, Oxford, UK.; Department of Haematology and BRC Haematology Theme, Churchill Hospital, Headington, Oxford, UK., Danesh J; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Department of Human Genetics, the Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, UK., Burchell B; Magdalene College, Cambridge, UK., Furlotte NA; 23andMe, Inc., Sunnyvale, CA, USA., Nandakumar P; 23andMe, Inc., Sunnyvale, CA, USA., Earley CJ; Center for Restless Legs Syndrome, Department of Neurology, Johns Hopkins University, Baltimore, MD, USA., Ondo WG; Department of Neurology, Methodist Neurological Institute, Weill Cornell Medical School, Houston, TX, USA., Xiong L; The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada., Desautels A; Centre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada.; Department of Neurosciences, Université de Montréal, Montreal, Quebec, Canada., Perola M; Clinical and Molecular Metabolism Research Program (CAMM), Faculty of Medicine, University of Helsinki, Helsinki, Finland.; Department of Public Health and Welfare, National Institute for Health and Welfare, Helsinki, Finland., Vodicka P; Department of Molecular Biology of Cancer, Institute of Experimental Medicine, Academy of Science of Czech Republic, Prague, Czech Republic.; First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; Biomedical Centre, Faculty of Medicine in Pilsen, Charles University in Prague, Pilsen, Czech Republic., Dina C; L'institut du thorax, CNRS, INSERM, Nantes Université, Nantes, France., Stoll M; Department of Genetic Epidemiology, Institute for Human Genetics, University of Münster, Münster, Germany., Franke A; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Lieb W; PopGen Biobank and Institute of Epidemiology, Christian Albrechts University Kiel, Kiel, Germany., Stewart AFR; John and Jennifer Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Ontario, Canada., Shah SH; Department of Medicine, Duke University School of Medicine, Durham, NC, USA.; Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA., Gieger C; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Peters A; Institute of Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; German Research Center for Cardiovascular Disease (DZHK), partner site Munich Heart Alliance, Hannover, Germany.; Chair of Epidemiology, Institute for Medical Information Processing, Biometry and Epidemiology, Medical Faculty, Ludwig-Maximilians-Universität München, Munich, Germany., Rye DB; Department of Neurology, Emory University, Atlanta, GA, USA., Rouleau GA; The Neuro (Montreal Neurological Institute-Hospital), McGill University, Montreal, Quebec, Canada.; Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.; Department of Human Genetics, McGill University, Montreal, Quebec, Canada., Berger K; Institute of Epidemiology and Social Medicine, University of Münster, Münster, Germany., Stefansson H; deCODE Genetics/Amgen, Reykjavik, Iceland., Ullum H; Statens Serum Institute, Copenhagen, Denmark., Stefansson K; deCODE Genetics/Amgen, Reykjavik, Iceland., Hinds DA; 23andMe, Inc., Sunnyvale, CA, USA., Di Angelantonio E; British Heart Foundation Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Centre of Research Excellence, University of Cambridge, Cambridge, UK.; National Institute for Health and Care Research Blood and Transplant Research Unit in Donor Health and Behaviour, University of Cambridge, Cambridge, UK.; Health Data Research UK Cambridge, Wellcome Genome Campus and University of Cambridge, Cambridge, UK.; Victor Phillip Dahdaleh Heart and Lung Research Institute, University of Cambridge, Cambridge, UK.; Health Data Science Research Centre, Fondazione Human Technopole, Milan, Italy., Oexle K; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; Neurogenetic Systems Analysis Group, Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Winkelmann J; Institute of Neurogenomics, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, TUM School of Medicine and Health, Technical University of Munich, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Center for Mental Health (DZPG), partner site Munich-Augsburg, Munich-Augsburg, Germany.
Publikováno v:
Nature genetics [Nat Genet] 2024 Jun; Vol. 56 (6), pp. 1090-1099. Date of Electronic Publication: 2024 Jun 05.
Autor:
Turcot V; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research, LLC, San Diego, CA, USA., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Hendricks AE; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Sivapalaratnam S; Department of Vascular Medicine, AMC, Amsterdam, the Netherlands.; Massachusetts General Hospital, Boston, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Alfred T; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Aben KK; Netherlands Comprehensive Cancer Organisation, Utrecht, the Netherlands.; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada., Alharthi SE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Allison M; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Auer PL; Zilber School of Public Health, University of Wisconsin- Milwaukee, Milwaukee, WI, USA., Balkau B; INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France., Bang LE; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, UK.; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Benn M; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Breen G; MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK., Brilliant MH; Marshfield Clinic Research Institute, Marshfield, WI, USA., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Burt AA; Department of Medicine, University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Campbell PT; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Carey DJ; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chambers JC; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, MA, USA.; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Cocca M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Galbany JC; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA., Cuellar-Partida G; Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., D'Eustacchio A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Danesh J; Wellcome Trust Sanger Institute, Hinxton, UK.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Davies G; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Groot MCH; Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, the Netherlands., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Heijer M; Department of Internal Medicine, VU University Medical Center, Amsterdam, the Netherlands., Hollander AI; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands., Ruijter HM; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Du M; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dubé MP; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Health Sciences, University of Leicester, Leicester, UK., Farooqi IS; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauser S; Department of Ophthalmology, University of Cologne, Cologne, Germany., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Ford I; University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Frikke-Schmidt R; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Galesloot TE; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Gibson J; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Gjesing AP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gordon-Larsen P; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany., Grant SFA; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Griffiths HL; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Grove ML; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hammerschlag AR; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris KM; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Sociology, University of North Carolina, Chapel Hill, NC, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Heath AC; Department of Psychiatry, Washington University, St. Louis, MO, USA., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Helgeland Ø; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Hernesniemi J; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.; Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia., Holmen OL; KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, the Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Huang PL; Massachusetts General Hospital, Boston, MA, USA., Huffman JE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, the Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jansson JH; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Research Unit Skellefteå, Skellefteå, Sweden., Jarvik GP; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jensen GB; Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Jørgensen ME; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Jørgensen T; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Kahn RS; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands., Kähönen M; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kamstrup PR; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kaprio J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Kim E; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Korhonen T; Department of Public Health, University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kuivaniemi H; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lange EM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Li J; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Lin KH; Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Lin LA; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lo KS; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Lotery AJ; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Loukola A; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Mazul AL, McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mistry V; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Mitchell P; Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, the Netherlands., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mori TA; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Morris AD; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Njølstad PR; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., O'Connel JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., O'Donoghue ML; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Loohuis LMO; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Ophoff RA; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; University of Glasgow, Glasgow, UK., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pasterkamp G; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, the Netherlands., Patel AP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peissig PL; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Perola M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Person TN; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peters A; German Center for Diabetes Research, Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Petersen ERB; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pirie A; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Polasek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; School of Medicine, University of Split, Split, Croatia., Polderman TJ; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, the Netherlands., Puolijoki H; Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rioux JD; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Rivas MA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Sapkota Y; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sattar N; University of Glasgow, Glasgow, UK., Schoen RE; Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Schreiner PJ; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe MP; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Shah SH; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft at Qiagen Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Southam L; Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Sun L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Tada H; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Kanazawa University, Kanazawa, Japan., Tansey KE; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK., Tardif JC; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Taylor KD; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson DJ; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thuesen BH; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Tönjes A; Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany., Tromp G; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., Tuomilehto J; National Institute for Health and Welfare, Helsinki, Finland.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Dasman Diabetes Institute, Dasman, Kuwait.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tybjaerg-Hansen A; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Uher R; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Laan SW; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands., Leeuwen N; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, the Netherlands.; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, the Netherlands., van Setten J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, the Netherlands., Vanhala M; Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland., Varbo A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Edwards DRV; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Vermeulen SH; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, the Netherlands., Veronesi G; Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Wang CA; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Ware EB; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Waterworth DM; Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA., Wessel J; Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA., White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Witte DR; Danish Diabetes Academy, Odense, Denmark.; Department of Public Health, Aarhus University, Aarhus, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yao J; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yao P; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; GlaxoSmithKline, King of Prussia, PA, USA., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; University of Glasgow, Glasgow, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Zhan X; Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zondervan KT; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, the Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.; Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature genetics [Nat Genet] 2019 Jul; Vol. 51 (7), pp. 1191-1192.
Autor:
Turcot V; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research, LLC, San Diego, CA, USA., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Hendricks AE; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Sivapalaratnam S; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.; Massachusetts General Hospital, Boston, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Alfred T; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Aben KK; Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada., Alharthi SE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Allison M; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Balkau B; INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France., Bang LE; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, UK.; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Benn M; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Breen G; MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK., Brilliant MH; Marshfield Clinic Research Institute, Marshfield, WI, USA., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Burt AA; Department of Medicine, University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Campbell PT; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Carey DJ; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chambers JC; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, MA, USA.; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Cocca M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Corominas Galbany J; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA., Cuellar-Partida G; Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., D'Eustacchio A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Danesh J; Wellcome Trust Sanger Institute, Hinxton, UK.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Davies G; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Groot MCH; Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Deary IJ; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Heijer M; Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands., Hollander AI; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Ruijter HM; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Du M; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dubé MP; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Health Sciences, University of Leicester, Leicester, UK., Farooqi IS; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauser S; Department of Ophthalmology, University of Cologne, Cologne, Germany., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Ford I; University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Frikke-Schmidt R; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Galesloot TE; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Gibson J; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Gjesing AP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gordon-Larsen P; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany., Grant SFA; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Griffiths HL; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Grove ML; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hammerschlag AR; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris KM; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Sociology, University of North Carolina, Chapel Hill, NC, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Heath AC; Department of Psychiatry, Washington University, St. Louis, MO, USA., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Helgeland Ø; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Hernesniemi J; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.; Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia., Holmen OL; KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Huang PL; Massachusetts General Hospital, Boston, MA, USA., Huffman JE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jansson JH; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Research Unit Skellefteå, Skellefteå, Sweden., Jarvik GP; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jensen GB; Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Jørgensen ME; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Jørgensen T; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Kahn RS; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., Kähönen M; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kamstrup PR; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kaprio J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Kim E; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Korhonen T; Department of Public Health, University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kuivaniemi H; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lange EM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Li J; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Lin KH; Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Lin LA; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lo KS; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Lotery AJ; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Loukola A; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Mazul AL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mistry V; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Mitchell P; Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mori TA; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Morris AD; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Njølstad PR; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., O'Connel JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., O'Donoghue ML; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Olde Loohuis LM; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Ophoff RA; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; University of Glasgow, Glasgow, UK., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pasterkamp G; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., Patel AP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peissig PL; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Perola M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Person TN; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peters A; German Center for Diabetes Research, Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Petersen ERB; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pirie A; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Polasek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; School of Medicine, University of Split, Split, Croatia., Polderman TJ; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Puolijoki H; Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rioux JD; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Rivas MA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Sapkota Y; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sattar N; University of Glasgow, Glasgow, UK., Schoen RE; Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Schreiner PJ; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe MP; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Shah SH; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft at Qiagen Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Southam L; Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Sun L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Tada H; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Kanazawa University, Kanazawa, Japan., Tansey KE; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK., Tardif JC; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Taylor KD; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson DJ; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thuesen BH; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Tönjes A; Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany., Tromp G; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., Tuomilehto J; National Institute for Health and Welfare, Helsinki, Finland.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Dasman Diabetes Institute, Dasman, Kuwait.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tybjaerg-Hansen A; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Uher R; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Laan SW; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Leeuwen N; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., van Setten J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Vanhala M; Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland., Varbo A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Velez Edwards DR; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Vermeulen SH; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Veronesi G; Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Wang CA; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Ware EB; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Waterworth DM; Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA., Wessel J; Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA., White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Witte DR; Danish Diabetes Academy, Odense, Denmark.; Department of Public Health, Aarhus University, Aarhus, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yao J; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yao P; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; GlaxoSmithKline, King of Prussia, PA, USA., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; University of Glasgow, Glasgow, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Zhan X; Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zondervan KT; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.; Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature genetics [Nat Genet] 2018 May; Vol. 50 (5), pp. 765-766.
Autor:
Turcot V; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research, LLC, San Diego, CA, USA., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Hendricks AE; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Sivapalaratnam S; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.; Massachusetts General Hospital, Boston, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Alfred T; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Aben KK; Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada., Alharthi SE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Allison M; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Balkau B; INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France., Bang LE; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, UK.; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Benn M; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Breen G; MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK., Brilliant MH; Marshfield Clinic Research Institute, Marshfield, WI, USA., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Burt AA; Department of Medicine, University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Campbell PT; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Carey DJ; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chambers JC; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, MA, USA.; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Cocca M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Corominas Galbany J; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA., Cuellar-Partida G; Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., D'Eustacchio A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Danesh J; Wellcome Trust Sanger Institute, Hinxton, UK.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Davies G; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Groot MCH; Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Deary IJ; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Heijer M; Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands., Hollander AI; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Ruijter HM; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Du M; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dubé MP; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Health Sciences, University of Leicester, Leicester, UK., Farooqi IS; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauser S; Department of Ophthalmology, University of Cologne, Cologne, Germany., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Ford I; University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Frikke-Schmidt R; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Galesloot TE; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Gibson J; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Gjesing AP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gordon-Larsen P; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany., Grant SFA; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Griffiths HL; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Grove ML; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hammerschlag AR; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris KM; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Sociology, University of North Carolina, Chapel Hill, NC, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Heath AC; Department of Psychiatry, Washington University, St. Louis, MO, USA., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Helgeland Ø; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Hernesniemi J; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.; Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia., Holmen OL; KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Huang PL; Massachusetts General Hospital, Boston, MA, USA., Huffman JE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jansson JH; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Research Unit Skellefteå, Skellefteå, Sweden., Jarvik GP; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jensen GB; Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Jørgensen ME; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Jørgensen T; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Kahn RS; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., Kähönen M; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kamstrup PR; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kaprio J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Kim E; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Korhonen T; Department of Public Health, University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kuivaniemi H; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lange EM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Li J; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Lin KH; Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Lin LA; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lo KS; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Lotery AJ; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Loukola A; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Mazul AL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mistry V; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Mitchell P; Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mori TA; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Morris AD; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Njølstad PR; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., O'Connel JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., O'Donoghue ML; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Olde Loohuis LM; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Ophoff RA; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; University of Glasgow, Glasgow, UK., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pasterkamp G; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., Patel AP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peissig PL; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Perola M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Person TN; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peters A; German Center for Diabetes Research, Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Petersen ERB; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pirie A; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Polasek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; School of Medicine, University of Split, Split, Croatia., Polderman TJ; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Puolijoki H; Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rioux JD; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Rivas MA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Sapkota Y; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sattar N; University of Glasgow, Glasgow, UK., Schoen RE; Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Schreiner PJ; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe MP; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Shah SH; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft at Qiagen Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Southam L; Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Sun L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Tada H; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Kanazawa University, Kanazawa, Japan., Tansey KE; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK., Tardif JC; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Taylor KD; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson DJ; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thuesen BH; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Tönjes A; Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany., Tromp G; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., Tuomilehto J; National Institute for Health and Welfare, Helsinki, Finland.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Dasman Diabetes Institute, Dasman, Kuwait.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tybjaerg-Hansen A; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Uher R; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Laan SW; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Leeuwen N; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., van Setten J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Vanhala M; Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland., Varbo A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Velez Edwards DR; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Vermeulen SH; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Veronesi G; Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Wang CA; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Ware EB; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Waterworth DM; Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA., Wessel J; Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA., White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Witte DR; Danish Diabetes Academy, Odense, Denmark.; Department of Public Health, Aarhus University, Aarhus, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yao J; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yao P; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; GlaxoSmithKline, King of Prussia, PA, USA., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; University of Glasgow, Glasgow, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Zhan X; Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zondervan KT; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.; Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature genetics [Nat Genet] 2018 May; Vol. 50 (5), pp. 766-767.
Autor:
Turcot V; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lu Y; Division of Epidemiology, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt Epidemiology Center, Vanderbilt University School of Medicine, Nashville, TN, USA.; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Highland HM; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA.; Human Genetics Center, University of Texas School of Public Health, University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences, University of Texas Health Science Center at Houston, Houston, TX, USA., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Justice AE; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Fine RS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Bradfield JP; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Quantinuum Research, LLC, San Diego, CA, USA., Esko T; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia., Giri A; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Graff M; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Guo X; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Hendricks AE; Wellcome Trust Sanger Institute, Hinxton, UK.; Department of Mathematical and Statistical Sciences, University of Colorado, Denver, CO, USA., Karaderi T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biological Sciences, Faculty of Arts and Sciences, Eastern Mediterranean University, Famagusta, Cyprus., Lempradl A; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Locke AE; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; McDonnell Genome Institute, Washington University School of Medicine, St. Louis, MO, USA., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Marouli E; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Sivapalaratnam S; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands.; Massachusetts General Hospital, Boston, MA, USA.; Department of Haematology, University of Cambridge, Cambridge, UK., Young KL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., Alfred T; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Masca NGD; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Manning AK; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Medina-Gomez C; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Mudgal P; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Ng MCY; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA., Reiner AP; Department of Epidemiology, University of Washington, Seattle, WA, USA.; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Vedantam S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Department of Genetics, Harvard Medical School, Boston, MA, USA.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA., Willems SM; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Winkler TW; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany., Abecasis G; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Aben KK; Netherlands Comprehensive Cancer Organisation, Utrecht, The Netherlands.; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Alam DS; School of Kinesiology and Health Science, Faculty of Health, York University, Toronto, Ontario, Canada., Alharthi SE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Allison M; Department of Family Medicine and Public Health, University of California, San Diego, La Jolla, CA, USA., Amouyel P; INSERM U1167, Lille, France.; Institut Pasteur de Lille, U1167, Lille, France.; Université de Lille, U1167, RID-AGE, Risk Factors and Molecular Determinants of Aging-Related Diseases, Lille, France., Asselbergs FW; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Durrer Center for Cardiogenetic Research, ICIN-Netherlands Heart Institute, Utrecht, The Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Auer PL; Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, WI, USA., Balkau B; INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations (CESP), Villejuif, France., Bang LE; Department of Cardiology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Barroso I; Wellcome Trust Sanger Institute, Hinxton, UK.; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bastarache L; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Benn M; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bergmann S; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Bielak LF; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Blüher M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Boehnke M; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Boeing H; Department of Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany., Boerwinkle E; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX, USA., Böger CA; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Bork-Jensen J; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Bots ML; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands., Bottinger EP; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Bowden DW; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Brandslund I; Department of Clinical Biochemistry, Lillebaelt Hospital, Vejle, Denmark.; Institute of Regional Health Research, University of Southern Denmark, Odense, Denmark., Breen G; MRC Social Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; NIHR Biomedical Research Centre for Mental Health, South London and Maudsley Hospital, London, UK., Brilliant MH; Marshfield Clinic Research Institute, Marshfield, WI, USA., Broer L; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Brumat M; Department of Medical Sciences, University of Trieste, Trieste, Italy., Burt AA; Department of Medicine, University of Washington, Seattle, WA, USA., Butterworth AS; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Campbell PT; Epidemiology Research Program, American Cancer Society, Atlanta, GA, USA., Cappellani S; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Carey DJ; Weis Center for Research, Geisinger Health System, Danville, PA, USA., Catamo E; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Caulfield MJ; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Chambers JC; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Chasman DI; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Chen YI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Chowdhury R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Christensen C; Medical Department, Lillebaelt Hospital, Vejle, Denmark., Chu AY; NHLBI Framingham Heart Study, Framingham, MA, USA.; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Cocca M; Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy., Collins FS; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Cook JP; Department of Biostatistics, University of Liverpool, Liverpool, UK., Corley J; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Corominas Galbany J; Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands.; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Cox AJ; Center for Diabetes Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC, USA.; Menzies Health Institute Queensland, Griffith University, Southport, Queensland, Australia., Crosslin DS; Department of Biomedical Informatics and Medical Education, University of Washington, Seattle, WA, USA., Cuellar-Partida G; Diamantina Institute, University of Queensland, Brisbane, Queensland, Australia.; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., D'Eustacchio A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Danesh J; Wellcome Trust Sanger Institute, Hinxton, UK.; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; British Heart Foundation Cambridge Centre of Excellence, Department of Medicine, University of Cambridge, Cambridge, UK., Davies G; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Bakker PIW; Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, The Netherlands.; Department of Genetics, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht, The Netherlands., Groot MCH; Department of Clinical Chemistry and Haematology, Division of Laboratory and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands.; Utrecht Institute for Pharmaceutical Sciences, Division Pharmacoepidemiology and Clinical Pharmacology, Utrecht University, Utrecht, The Netherlands., Mutsert R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Deary IJ; Department of Biostatistics, University of Liverpool, Liverpool, UK.; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Dedoussis G; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece., Demerath EW; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Heijer M; Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands., Hollander AI; Department of Ophthalmology, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, The Netherlands., Ruijter HM; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Dennis JG; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Denny JC; Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA., Di Angelantonio E; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Drenos F; Institute of Cardiovascular Science, University College London, London, UK.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK., Du M; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.; Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY, USA., Dubé MP; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Dunning AM; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Easton DF; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Edwards TL; Division of Epidemiology, Department of Medicine, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Ellinghaus D; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Ellinor PT; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Elliott P; Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Evangelou E; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK.; Department of Hygiene and Epidemiology, University of Ioannina Medical School, Ioannina, Greece., Farmaki AE; Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University, Athens, Greece.; Department of Health Sciences, University of Leicester, Leicester, UK., Farooqi IS; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Faul JD; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Fauser S; Department of Ophthalmology, University of Cologne, Cologne, Germany., Feng S; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Ferrannini E; CNR Institute of Clinical Physiology, Pisa, Italy.; Department of Clinical and Experimental Medicine, University of Pisa, Pisa, Italy., Ferrieres J; Toulouse University School of Medicine, Toulouse, France., Florez JC; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Ford I; University of Glasgow, Glasgow, UK., Fornage M; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Franco OH; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, MA, USA.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, Umeå, Sweden., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Frikke-Schmidt R; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Galesloot TE; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Gan W; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gandin I; Research Unit, AREA Science Park, Trieste, Italy., Gasparini P; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Gibson J; Centre for Biological Sciences, Faculty of Natural and Environmental Sciences, University of Southampton, Southampton, UK., Giedraitis V; Geriatrics, Department of Public Health, Uppsala University, Uppsala, Sweden., Gjesing AP; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Gordon-Larsen P; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Nutrition, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, NC, USA., Gorski M; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Grabe HJ; Department of Psychiatry and Psychotherapy, University Medicine Greifswald, Greifswald, Germany.; German Center for Neurodegenerative Diseases (DZNE), Rostock/Greifswald, Greifswald, Germany., Grant SFA; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Griffiths HL; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Grove ML; School of Public Health, Human Genetics Center, University of Texas Health Science Center at Houston, Houston, TX, USA., Gudnason V; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Haessler J; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Hakonarson H; Center for Applied Genomics, Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Hammerschlag AR; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris KM; Carolina Population Center, University of North Carolina, Chapel Hill, NC, USA.; Department of Sociology, University of North Carolina, Chapel Hill, NC, USA., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Intramural Research Program, US National Institutes of Health, Bethesda, MD, USA., Hattersley AT; University of Exeter Medical School, University of Exeter, Exeter, UK., Have CT; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., He L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Heard-Costa NL; NHLBI Framingham Heart Study, Framingham, MA, USA.; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Heath AC; Department of Psychiatry, Washington University, St. Louis, MO, USA., Heid IM; Department of Genetic Epidemiology, University of Regensburg, Regensburg, Germany.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Helgeland Ø; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Hernesniemi J; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Hewitt AW; Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Victoria, Australia.; Centre for Ophthalmology and Vision Science, Lions Eye Institute, University of Western Australia, Perth, Western Australia, Australia.; Menzies Research Institute Tasmania, University of Tasmania, Hobart, Tasmania, Australia., Holmen OL; KG Jebsen Center for Genetic Epidemiology, Department of Public Health, NTNU, Norwegian University of Science and Technology, Trondheim, Norway., Hovingh GK; Department of Vascular Medicine, AMC, Amsterdam, The Netherlands., Howson JMM; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Hu Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Huang PL; Massachusetts General Hospital, Boston, MA, USA., Huffman JE; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Radiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Jackson AU; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Jansson JH; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Research Unit Skellefteå, Skellefteå, Sweden., Jarvik GP; Department of Medicine, University of Washington, Seattle, WA, USA.; Department of Genome Sciences, University of Washington, Seattle, WA, USA., Jensen GB; Copenhagen City Heart Study, Frederiksberg Hospital, Frederiksberg, Denmark., Jia Y; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Johansson S; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway.; Center for Medical Genetics and Molecular Medicine, Haukeland University Hospital, Bergen, Norway., Jørgensen ME; National Institute of Public Health, University of Southern Denmark, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Jørgensen T; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Faculty of Medicine, Aalborg University, Aalborg, Denmark.; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Kahali B; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA.; Centre for Brain Research, Indian Institute of Science, Bangalore, India., Kahn RS; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands., Kähönen M; Department of Clinical Physiology, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland., Kamstrup PR; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Kaprio J; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Karaleftheri M; Echinos Medical Centre, Echinos, Greece., Kardia SLR; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Kathiresan S; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Kee F; UKCRC Centre of Excellence for Public Health Research, Queens University Belfast, Belfast, UK., Kiemeney LA; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Kim E; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Kitajima H; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Komulainen P; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Kooner JS; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; National Heart and Lung Institute, Imperial College London, Hammersmith Hospital Campus, London, UK.; MRC-PHE Centre for Environment and Health, Imperial College London, London, UK., Kooperberg C; Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA., Korhonen T; Department of Public Health, University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Kovacs P; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany., Kuivaniemi H; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Department of Psychiatry, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Kutalik Z; Swiss Institute of Bioinformatics, Lausanne, Switzerland.; Institute of Social and Preventive Medicine, Lausanne University Hospital, Lausanne, Switzerland., Kuulasmaa K; National Institute for Health and Welfare, Helsinki, Finland., Kuusisto J; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Laakso M; Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland and Kuopio University Hospital, Kuopio, Finland., Lakka TA; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland.; Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lamparter D; Department of Computational Biology, University of Lausanne, Lausanne, Switzerland.; Swiss Institute of Bioinformatics, Lausanne, Switzerland., Lange EM; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Lange LA; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Larson EB; Department of Medicine, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA.; Department of Health Services, University of Washington, Seattle, WA, USA., Lee NR; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines.; USC-Office of Population Studies Foundation, Inc., University of San Carlos, Cebu City, Philippines., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Lewis CE; Division of Preventive Medicine, University of Alabama at Birmingham, Birmingham, AL, USA., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Li J; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Li-Gao R; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Lin H; Department of Medicine, Boston University School of Medicine, Boston, MA, USA., Lin KH; Department of Ophthalmology, Taichung Veterans General Hospital, Taichung, Taiwan., Lin LA; Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, TX, USA., Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindström J; National Institute for Health and Welfare, Helsinki, Finland., Linneberg A; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Liu CT; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Liu DJ; Department of Public Health Sciences, Institute for Personalized Medicine, Pennsylvania State University College of Medicine, Hershey, PA, USA., Liu Y; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Lo KS; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Lophatananon A; Division of Health Sciences, Warwick Medical School, Warwick University, Coventry, UK., Lotery AJ; Vision Sciences, Clinical Neurosciences Research Group, Faculty of Medicine, University of Southampton, Southampton, UK., Loukola A; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Lubitz SA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Medical and Population Genetics Program, Broad Institute, Cambridge, MA, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, Finnish Cardiovascular Research Center-Tampere, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Männistö S; National Institute for Health and Welfare, Helsinki, Finland., Marenne G; Wellcome Trust Sanger Institute, Hinxton, UK., Mazul AL; Department of Epidemiology, University of North Carolina, Chapel Hill, NC, USA., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., McKean-Cowdin R; Department of Preventive Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Medland SE; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Meidtner K; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mistry V; Metabolic Research Laboratories, University of Cambridge, Cambridge, UK.; NIHR Cambridge Biomedical Research Centre, Wellcome Trust-MRC Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Mitchell P; Westmead Millennium Institute of Medical Research, Centre for Vision Research and Department of Ophthalmology, University of Sydney, Sydney, New South Wales, Australia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Moilanen L; Department of Medicine, Kuopio University Hospital, Kuopio, Finland., Moitry M; Department of Epidemiology and Public Health, University of Strasbourg, Strasbourg, France.; Department of Public Health, University Hospital of Strasbourg, Strasbourg, France., Montgomery GW; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute for Molecular Bioscience, University of Queensland, Brisbane, Queensland, Australia., Mook-Kanamori DO; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Public Health and Primary Care, Leiden University Medical Center, Leiden, The Netherlands., Moore C; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; INTERVAL Coordinating Centre, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Mori TA; School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia., Morris AD; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Großhadern, Ludwig-Maximilians-Universitat, Munich, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Munroe PB; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, MD, USA.; Data Tecnica International, Glen Echo, MD, USA., Narisu N; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Neville M; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Nielsen SF; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nikus K; Department of Cardiology, Heart Center, Tampere University Hospital and Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland., Njølstad PR; Department of Pediatrics, Haukeland University Hospital, Bergen, Norway.; KG Jebsen Center for Diabetes Research, Department of Clinical Science, University of Bergen, Bergen, Norway., Nordestgaard BG; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Nyholt DR; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia.; Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Queensland, Australia., O'Connel JR; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., O'Donoghue ML; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Olde Loohuis LM; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Ophoff RA; Department of Psychiatry, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.; Center for Neurobehavioral Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Owen KR; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Oxford NIHR Biomedical Research Centre, Oxford University Hospitals Trust, Oxford, UK., Packard CJ; University of Glasgow, Glasgow, UK., Padmanabhan S; University of Glasgow, Glasgow, UK., Palmer CNA; Pat Macpherson Centre for Pharmacogenetics and Pharmacogenomics, Medical Research Institute, Ninewells Hospital and Medical School, Dundee, UK., Palmer ND; Department of Biochemistry, Wake Forest School of Medicine, Winston-Salem, NC, USA., Pasterkamp G; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands.; Laboratory of Clinical Chemistry and Hematology, Division of Laboratories and Pharmacy, University Medical Center Utrecht, Utrecht, The Netherlands., Patel AP; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Massachusetts General Hospital, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA., Pattie A; Department of Psychology, University of Edinburgh, Edinburgh, UK., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Peissig PL; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peloso GM; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Pennell CE; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Perola M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland.; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland., Perry JA; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA., Perry JRB; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Pers TH; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Person TN; Marshfield Clinic Research Institute, Marshfield, WI, USA., Peters A; German Center for Diabetes Research, Neuherberg, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Petersen ERB; Department of Clinical Immunology and Biochemistry, Lillebaelt Hospital, Vejle, Denmark., Peyser PA; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Pirie A; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Polasek O; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK.; School of Medicine, University of Split, Split, Croatia., Polderman TJ; Department of Complex Trait Genetics, Center for Neurogenomics and Cognitive Research, Amsterdam Neuroscience, VU University Amsterdam, Amsterdam, The Netherlands., Puolijoki H; Central Hospital of Southern Ostrobothnia, Seinäjoki, Finland., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Rasheed A; Centre for Non-Communicable Diseases, Karachi, Pakistan., Rauramaa R; Foundation for Research in Health Exercise and Nutrition, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland.; Institute of Biomedicine, School of Medicine, University of Eastern Finland, Kuopio Campus, Kuopio, Finland., Reilly DF; Genetics and Pharmacogenomics, Merck, Sharp & Dohme, Boston, MA, USA., Renström F; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden.; Department of Biobank Research, Umeå University, Umeå, Sweden., Rheinberger M; Department of Nephrology, University Hospital Regensburg, Regensburg, Germany., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Harvard Medical School, Boston, MA, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Rioux JD; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., Rivas MA; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Wellcome Trust Centre for Human Genetics, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK., Roberts DJ; NIHR Blood and Transplant Research Unit in Donor Health and Genomics, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; NHS Blood and Transplant-Oxford Centre, Oxford, UK.; BRC Haematology Theme and Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robertson NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Robino A; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Rolandsson O; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.; Department of Public Health and Clinical Medicine, Unit of Family Medicine, Umeå University, Umeå, Sweden., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh, UK., Ruth KS; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Saleheen D; Centre for Non-Communicable Diseases, Karachi, Pakistan.; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Salomaa V; National Institute for Health and Welfare, Helsinki, Finland., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Sapkota Y; QIMR Berghofer Medical Research Institute, Brisbane, Queensland, Australia., Sattar N; University of Glasgow, Glasgow, UK., Schoen RE; Departments of Medicine and Epidemiology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA., Schreiner PJ; Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, MN, USA., Schulze MB; Department of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbrücke (DIfE), Nuthetal, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Segura-Lepe MP; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Shah SH; Duke Molecular Physiology Institute, Duke University, Durham, NC, USA., Sheu WH; Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.; School of Medicine, National Defense Medical Center, Taipei, Taiwan.; School of Medicine, National Yang-Ming University, Taipei, Taiwan., Sim X; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA.; Saw Swee Hock School of Public Health, National University Health System, National University of Singapore, Singapore, Singapore., Slater AJ; Genetics, Target Sciences, GlaxoSmithKline, Research Triangle Park, NC, USA.; OmicSoft at Qiagen Company, Cary, NC, USA., Small KS; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Smith AV; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; Icelandic Heart Association, Kopavogur, Iceland., Southam L; Wellcome Trust Sanger Institute, Hinxton, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London, UK., Speliotes EK; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Division of Gastroenterology, University of Michigan, Ann Arbor, MI, USA., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stefansson K; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Steinthorsdottir V; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Stirrups KE; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Genetic Epidemiology, IBE, Faculty of Medicine, LMU Munich, Munich, Germany., Stringham HM; Department of Biostatistics and Center for Statistical Genetics, University of Michigan, Ann Arbor, MI, USA., Stumvoll M; IFB Adiposity Diseases, University of Leipzig, Leipzig, Germany.; Department of Medicine, University of Leipzig, Leipzig, Germany., Sun L; Biodemography of Aging Research Unit, Social Science Research Institute, Duke University, Durham, NC, USA.; Department of Public Health, University of Helsinki, Helsinki, Finland., Surendran P; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Swift AJ; Medical Genomics and Metabolic Genetics Branch, National Human Genome Research Institute, US National Institutes of Health, Bethesda, MD, USA., Tada H; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Kanazawa University, Kanazawa, Japan., Tansey KE; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol, UK.; College of Biomedical and Life Sciences, Cardiff University, Cardiff, UK., Tardif JC; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada., Taylor KD; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Thompson DJ; Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Thorleifsson G; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thorsteinsdottir U; Faculty of Medicine, University of Iceland, Reykjavik, Iceland.; deCODE Genetics/Amgen, Inc., Reykjavik, Iceland., Thuesen BH; Research Center for Prevention and Health, Capital Region of Denmark, Glostrup, Denmark., Tönjes A; Center for Pediatric Research, Department for Women's and Child Health, University of Leipzig, Leipzig, Germany., Tromp G; Weis Center for Research, Geisinger Health System, Danville, PA, USA.; Division of Molecular Biology and Human Genetics, Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Tygerberg, South Africa., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Tsafantakis E; Anogia Medical Centre, Anogia, Greece., Tuomilehto J; National Institute for Health and Welfare, Helsinki, Finland.; Centre for Vascular Prevention, Danube University Krems, Krems, Austria.; Dasman Diabetes Institute, Dasman, Kuwait.; Diabetes Research Group, King Abdulaziz University, Jeddah, Saudi Arabia., Tybjaerg-Hansen A; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Clinical Biochemistry, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark., Tyrer JP; Centre for Cancer Genetic Epidemiology, Department of Oncology, University of Cambridge, Cambridge, UK., Uher R; Department of Psychiatry, Dalhousie University, Halifax, Nova Scotia, Canada., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Uusitupa M; Department of Public Health and Clinical Nutrition, University of Eastern Finland, Kuopio, Finland., Laan SW; Laboratory of Experimental Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Duijn CM; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Leeuwen N; Department of Epidemiology and Biostatistics, VU University Medical Center, Amsterdam, The Netherlands.; Department of Molecular Cell Biology, Leiden University Medical Center, Leiden, The Netherlands., van Setten J; Department of Cardiology, Division Heart and Lungs, University Medical Center Utrecht, Utrecht, The Netherlands., Vanhala M; Primary Health Care Unit, Central Hospital of Central Finland, Jyväskylä, Finland.; Primary Health Care Unit, Kuopio University Hospital, Kuopio, Finland., Varbo A; Department of Clinical Biochemistry, Herlev and Gentofte Hospital, Copenhagen University Hospital, Herlev, Denmark.; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Varga TV; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Lund University, Malmo, Sweden., Varma R; USC Roski Eye Institute, Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA., Velez Edwards DR; Department of Obstetrics and Gynecology, Institute for Medicine and Public Health, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, TN, USA., Vermeulen SH; Radboud Institute for Health Sciences, Radboud University Medical Center, Nijmegen, The Netherlands., Veronesi G; Research Center on Epidemiology and Preventive Medicine, Department of Medicine and Surgery, University of Insubria, Varese, Italy., Vestergaard H; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center Copenhagen, Gentofte, Denmark., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Vogt TF; Cardiometabolic Disease, Merck, Sharp & Dohme, Kenilworth, NJ, USA., Völker U; German Centre for Cardiovascular Research (DZHK), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Vuckovic D; Department of Medical Sciences, University of Trieste, Trieste, Italy.; Institute for Maternal and Child Health, IRCCS 'Burlo Garofolo', Trieste, Italy., Wagenknecht LE; Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, NC, USA., Walker M; Institute of Cellular Medicine, Medical School, Newcastle University, Newcastle, UK., Wallentin L; Department of Medical Sciences, Cardiology, Uppsala Clinical Research Center, Uppsala University, Uppsala, Sweden., Wang F; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Wang CA; School of Women's and Infants' Health, University of Western Australia, Perth, Western Australia, Australia., Wang S; Department of Biostatistics, Boston University School of Public Health, Boston, MA, USA., Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Ware EB; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA.; Survey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Warren HR; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; NIHR Barts Cardiovascular Research Unit, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Waterworth DM; Genetics, Target Sciences, GlaxoSmithKline, King of Prussia, PA, USA., Wessel J; Departments of Epidemiology and Medicine, Diabetes Translational Research Center, Fairbanks School of Public Health and School of Medicine, Indiana University, Indianapolis, IN, USA., White HD; Green Lane Cardiovascular Service, Auckland City Hospital and University of Auckland, Auckland, New Zealand., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA.; Department of Human Genetics, University of Michigan, Ann Arbor, MI, USA., Wilson JG; Department of Physiology and Biophysics, University of Mississippi Medical Center, Jackson, MS, USA., Witte DR; Danish Diabetes Academy, Odense, Denmark.; Department of Public Health, Aarhus University, Aarhus, Denmark., Wood AR; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, NC, USA., Yaghootkar H; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Yao J; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Yao P; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, University of the Chinese Academy of Sciences, Shanghai, China., Yerges-Armstrong LM; Program for Personalized and Genomic Medicine, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.; GlaxoSmithKline, King of Prussia, PA, USA., Young R; MRC/BHF Cardiovascular Epidemiology Unit, Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK.; University of Glasgow, Glasgow, UK., Zeggini E; Wellcome Trust Sanger Institute, Hinxton, UK., Zhan X; Department of Clinical Sciences, Quantitative Biomedical Research Center, Center for the Genetics of Host Defense, University of Texas Southwestern Medical Center, Dallas, TX, USA., Zhang W; Department of Cardiology, London North West Healthcare NHS Trust, Ealing Hospital, Middlesex, UK.; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, London, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, Cambridge, UK., Zhao W; Department of Biostatistics and Epidemiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Zhao W; Department of Epidemiology, School of Public Health, University of Michigan, Ann Arbor, MI, USA., Zhou W; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA.; Department of Internal Medicine, University of Michigan, Ann Arbor, MI, USA., Zondervan KT; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Endometriosis CaRe Centre, Nuffield Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Pospisilik JA; Max Planck Institute of Immunobiology and Epigenetics, Freiburg, Germany., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St. Louis, MO, USA., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Frayling TM; Genetics of Complex Traits, University of Exeter Medical School, University of Exeter, Exeter, UK., Lettre G; Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada.; Department of Medicine, Faculty of Medicine, Université de Montréal, Montreal, Quebec, Canada., North KE; Department of Epidemiology and Carolina Center of Genome Sciences, Chapel Hill, NC, USA., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Li Ka Shing Centre for Health Information and Discovery, Big Data Institute, University of Oxford, Oxford, UK., Hirschhorn JN; Broad Institute of MIT and Harvard, Cambridge, MA, USA. joelh@broadinstitute.org.; Department of Genetics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org.; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, MA, USA. joelh@broadinstitute.org.; Department of Pediatrics, Harvard Medical School, Boston, MA, USA. joelh@broadinstitute.org., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, NY, USA. ruth.loos@mssm.edu.
Publikováno v:
Nature genetics [Nat Genet] 2018 Jan; Vol. 50 (1), pp. 26-41. Date of Electronic Publication: 2017 Dec 22.
Autor:
Christophersen IE, Rienstra M, Roselli C, Yin X, Geelhoed B, Barnard J, Lin H, Arking DE, Smith AV, Albert CM, Chaffin M, Tucker NR, Li M, Klarin D, Bihlmeyer NA, Low SK, Weeke PE, Müller-Nurasyid M, Smith JG, Brody JA, Niemeijer MN, Dörr M, Trompet S, Huffman J, Gustafsson S, Schurmann C, Kleber ME, Lyytikäinen LP, Seppälä I, Malik R, R V R Horimoto A, Perez M, Sinisalo J, Aeschbacher S, Thériault S, Yao J, Radmanesh F, Weiss S, Teumer A, Choi SH, Weng LC, Clauss S, Deo R, Rader DJ, Shah SH, Sun A, Hopewell JC, Debette S, Chauhan G, Yang Q, Worrall BB, Paré G, Kamatani Y, Hagemeijer YP, Verweij N, Siland JE, Kubo M, Smith JD, Van Wagoner DR, Bis JC, Perz S, Psaty BM, Ridker PM, Magnani JW, Harris TB, Launer LJ, Shoemaker MB, Padmanabhan S, Haessler J, Bartz TM, Waldenberger M, Lichtner P, Arendt M, Krieger JE, Kähönen M, Risch L, Mansur AJ, Peters A, Smith BH, Lind L, Scott SA, Lu Y, Bottinger EB, Hernesniemi J, Lindgren CM, Wong JA, Huang J, Eskola M, Morris AP, Ford I, Reiner AP, Delgado G, Chen LY, Chen YI, Sandhu RK, Li M, Boerwinkle E, Eisele L, Lannfelt L, Rost N, Anderson CD, Taylor KD, Campbell A, Magnusson PK, Porteous D, Hocking LJ, Vlachopoulou E, Pedersen NL, Nikus K, Orho-Melander M, Hamsten A, Heeringa J, Denny JC, Kriebel J, Darbar D, Newton-Cheh C, Shaffer C, Macfarlane PW, Heilmann-Heimbach S, Almgren P, Huang PL, Sotoodehnia N, Soliman EZ, Uitterlinden AG, Hofman A, Franco OH, Völker U, Jöckel KH, Sinner MF, Lin HJ, Guo X, Dichgans M, Ingelsson E, Kooperberg C, Melander O, J F Loos R, Laurikka J, Conen D, Rosand J, van der Harst P, Lokki ML, Kathiresan S, Pereira A, Jukema JW, Hayward C, Rotter JI, März W, Lehtimäki T, Stricker BH, Chung MK, Felix SB, Gudnason V, Alonso A, Roden DM, Kääb S, Chasman DI, Heckbert SR, Benjamin EJ, Tanaka T, Lunetta KL, Lubitz SA, Ellinor PT
Publikováno v:
Nature genetics [Nat Genet] 2017 Jul 27; Vol. 49 (8), pp. 1286.
Autor:
Christophersen IE; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medical Research, Bærum Hospital, Vestre Viken Hospital Trust, Rud, Norway., Rienstra M; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Roselli C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany., Yin X; NHLBI and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Geelhoed B; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Barnard J; Departments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA., Lin H; NHLBI and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Albert CM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Chaffin M; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Tucker NR; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Li M; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Klarin D; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Bihlmeyer NA; Predoctoral Training Program in Human Genetics, McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA., Low SK; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Weeke PE; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Heart Centre, Department of Cardiology, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Smith JG; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Molecular Epidemiology and Cardiology, Clinical Sciences, Lund University, Lund, Sweden., Brody JA; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA., Niemeijer MN; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Dörr M; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Huffman J; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Gustafsson S; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Schurmann C; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Kleber ME; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere School of Medicine, Tampere, Finland., Seppälä I; Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere School of Medicine, Tampere, Finland., Malik R; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany., Horimoto ARVR; Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of São Paulo, São Paulo, Brazil., Perez M; Department of Cardiovascular Medicine, Stanford University, Stanford, California, USA., Sinisalo J; Heart and Lung Center HUS, Helsinki University Central Hospital, Helsinki, Finland., Aeschbacher S; Department of Medicine, University Hospital Basel, Basel, Switzerland.; Cardiovascular Research Institute Basel, Basel, Switzerland., Thériault S; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Yao J; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., Radmanesh F; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Weiss S; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst Moritz Arndt University Greifswald, Greifswald, Germany., Teumer A; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany., Choi SH; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Weng LC; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Clauss S; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Deo R; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rader DJ; Division of Cardiovascular Medicine, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Shah SH; Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Sun A; Division of Cardiology, Department of Medicine, Duke University School of Medicine, Durham, North Carolina, USA., Hopewell JC; CTSU-Nuffield Department of Population Health, University of Oxford, Oxford, UK., Debette S; INSERM U1219 (Bordeaux Population Health Centre), Bordeaux, France.; University of Bordeaux, Bordeaux, France.; Department of Neurology, Bordeaux University Hospital, Bordeaux, France.; Department of Neurology, Boston University School of Medicine, Boston, Massachusetts, USA., Chauhan G; INSERM U1219 (Bordeaux Population Health Centre), Bordeaux, France.; University of Bordeaux, Bordeaux, France., Yang Q; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Worrall BB; Departments of Neurology and Public Health Science, University of Virginia Health System, Charlottesville, Virginia, USA., Paré G; Population Health Research Institute, Hamilton, Ontario, Canada.; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Hagemeijer YP; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Siland JE; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Kubo M; RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Smith JD; Departments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA., Van Wagoner DR; Departments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA., Bis JC; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA., Perz S; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Psaty BM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA.; Department of Health Services, University of Washington, Seattle, Washington, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Cardiovascular Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Magnani JW; NHLBI and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA., Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA., Launer LJ; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, Bethesda, Maryland, USA., Shoemaker MB; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Padmanabhan S; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK., Haessler J; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, USA., Bartz TM; Cardiovascular Health Research Unit, Department of Medicine, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, Department of Biostatistics, University of Washington, Seattle, Washington, USA., Waldenberger M; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Arendt M; Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany., Krieger JE; Laboratory of Genetics and Molecular Cardiology, Heart Institute, University of São Paulo, São Paulo, Brazil., Kähönen M; Department of Clinical Physiology, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Risch L; University Institute of Clinical Chemistry, University of Bern, Bern, Switzerland.; Labormedizinisches Zentrum Dr. Risch, Schaan, Liechtenstein., Mansur AJ; Heart Institute, University of São Paulo, São Paulo, Brazil., Peters A; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Smith BH; Division of Population Health Sciences, University of Dundee, Dundee, UK., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Scott SA; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lu Y; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Bottinger EB; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Department of Pharmacology and Systems Therapeutics, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Hernesniemi J; Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere School of Medicine, Tampere, Finland.; Department of Cardiology, Heart Hospital, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Wong JA; Division of Cardiology, Hamilton Health Sciences, McMaster University, Hamilton, Ontario, Canada., Huang J; Boston VA Research Institute, Inc., Boston, Massachusetts, USA., Eskola M; Department of Cardiology, Heart Hospital, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Reiner AP; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Institute of Cardiovascular and Medical Sciences, BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK., Delgado G; Vth Department of Medicine, Medical Faculty Mannheim, Heidelberg University, Heidelberg, Germany., Chen LY; Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis, Minnesota, USA., Chen YI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., Sandhu RK; Division of Cardiology, University of Alberta, Edmonton, Alberta, Canada., Li M; Department of Epidemiology, Johns Hopkins University, Baltimore, Maryland, USA.; Division of Nephrology and Hypertension, Internal Medicine, School of Medicine, University of Utah, Salt Lake City, Utah, USA., Boerwinkle E; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA., Eisele L; Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany., Lannfelt L; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Rost N; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Acute Stroke Services, Massachusetts General Hospital, Boston, Massachusetts, USA., Anderson CD; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Taylor KD; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., Campbell A; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Porteous D; Generation Scotland, Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Hocking LJ; Musculoskeletal Research Programme, Division of Applied Medicine, University of Aberdeen, Aberdeen, UK., Vlachopoulou E; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Nikus K; Department of Cardiology, Heart Hospital, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Orho-Melander M; Department of Clinical Sciences, Lund University, Malmö, Sweden., Hamsten A; Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Heeringa J; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Denny JC; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kriebel J; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research, Neuherberg, Germany., Darbar D; Department of Medicine and Pharmacology, University of Illinois, Chicago, Illinois, USA., Newton-Cheh C; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Shaffer C; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Macfarlane PW; Institute of Health and Wellbeing, College of Medical, Veterinary and Life Sciences, University of Glasgow, Glasgow, UK., Heilmann-Heimbach S; Institute of Human Genetics, University of Bonn, Bonn, Germany.; Department of Genomics, Life and Brain Research Center, University of Bonn, Bonn, Germany., Almgren P; Department of Clinical Sciences, Lund University, Malmö, Sweden., Huang PL; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA., Sotoodehnia N; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA., Soliman EZ; Epidemiological Cardiology Research Center (EPICARE), Wake Forest School of Medicine, Winston-Salem, North Carolina, USA., Uitterlinden AG; Department of Epidemiology and Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Hofman A; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Franco OH; Department of Epidemiology, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands., Völker U; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine and Ernst Moritz Arndt University Greifswald, Greifswald, Germany., Jöckel KH; Institute of Medical Informatics, Biometry and Epidemiology, University Hospital Essen, Essen, Germany., Sinner MF; Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Lin HJ; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., Guo X; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., Dichgans M; Institute for Stroke and Dementia Research, Klinikum der Universität München, Ludwig-Maximilians-Universität, Munich, Germany.; Munich Cluster for Systems Neurology (SyNergy), Munich, Germany.; German Center for Neurodegenerative Diseases (DZNE), Munich, Germany., Ingelsson E; Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA., Kooperberg C; Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington, USA., Melander O; Department of Internal Medicine, Clinical Sciences, Lund University, Malmö, Sweden., Loos RJF; Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Genetics of Obesity and Related Metabolic Traits Program, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Laurikka J; Department of Cardio-Thoracic Surgery, Heart Hospital, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Conen D; Department of Medicine, University Hospital Basel, Basel, Switzerland.; Cardiovascular Research Institute Basel, Basel, Switzerland.; Population Health Research Institute, Hamilton, Ontario, Canada., Rosand J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Center for Human Genetics Research, Massachusetts General Hospital, Boston, Massachusetts, USA., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Lokki ML; Transplantation Laboratory, Medicum, University of Helsinki, Helsinki, Finland., Kathiresan S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Pereira A; Laboratory of Genetics and Molecular Biology, Heart Institute, University of São Paulo, São Paulo, Brazil.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam, the Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, the Netherlands., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK., Rotter JI; Institute for Translational Genomics and Population Sciences, Department of Pediatrics, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA.; Institute for Translational Genomics and Population Sciences, Department of Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, California, USA., März W; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Holding Deutschland GmbH, Mannheim and Augsburg, Germany., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories and University of Tampere School of Medicine, Tampere, Finland., Stricker BH; Department of Epidemiology and Internal Medicine, Erasmus University Medical Center Rotterdam, Rotterdam, the Netherlands.; Inspectorate of Health Care, Utrecht, the Netherlands., Chung MK; Departments of Cardiovascular Medicine, Cellular and Molecular Medicine, Molecular Cardiology, and Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio, USA., Felix SB; Department of Internal Medicine B, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, Greifswald, Germany., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Alonso A; Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, Georgia, USA., Roden DM; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kääb S; Department of Medicine I, University Hospital Munich, Ludwig Maximilians University, Munich, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, Munich, Germany., Chasman DI; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Division of Preventive Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Heckbert SR; Department of Epidemiology, University of Washington, Seattle, Washington, USA.; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington, USA.; Group Health Research Institute, Group Health Cooperative, Seattle, Washington, USA., Benjamin EJ; NHLBI and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.; Department of Epidemiology, Boston University School of Public Health, Boston, Massachusetts, USA., Tanaka T; Laboratory for Cardiovascular Diseases, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Human Genetics and Disease Diversity, Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences, Tokyo, Japan., Lunetta KL; NHLBI and Boston University's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Lubitz SA; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, USA., Ellinor PT; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Cardiac Arrhythmia Service, Massachusetts General Hospital, Boston, Massachusetts, USA.
Publikováno v:
Nature genetics [Nat Genet] 2017 Jun; Vol. 49 (6), pp. 946-952. Date of Electronic Publication: 2017 Apr 17.
Autor:
Nikpay M; Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Canada., Goel A; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Won HH; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., Hall LM; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK., Willenborg C; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.; DZHK (German Research Center for Cardiovascular Research) partner site Hamburg-Lübeck-Kiel, Lübeck, Germany., Kanoni S; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Saleheen D; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Center for Non-Communicable Diseases, Karachi, Pakistan., Kyriakou T; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Nelson CP; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Hopewell JC; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Webb TR; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Zeng L; Deutsches Herzzentrum München, Technische Universität München, München, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany., Dehghan A; Department of Epidemiology, Erasmus University Medical center, Rotterdam, The Netherlands., Alver M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., Armasu SM; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., Auro K; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Diabetes & Obesity Research Program, University of Helsinki, Helsinki, Finland., Bjonnes A; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA., Chasman DI; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Chen S; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Ford I; Robertson Center for Biostatistics, University of Glasgow, Glasgow, UK., Franceschini N; Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina, Chapel Hill, North Carolina, USA., Gieger C; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Grace C; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Gustafsson S; Molecular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden., Huang J; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK., Hwang SJ; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Kim YK; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Korea., Kleber ME; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany., Lau KW; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Lu X; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Morrison AC; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA., Pervjakova N; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Diabetes & Obesity Research Program, University of Helsinki, Helsinki, Finland., Qu L; Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Rose LM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Salfati E; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, California, USA., Saxena R; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Scholz M; Institute for Medical Informatics, Statistics and Epidemiology, Medical Faculty, University of Leipzig, Leipzig, Germany.; LIFE Research Center of Civilization Diseases, Leipzig, Germany., Smith AV; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Tikkanen E; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland., Uitterlinden A; Department of Epidemiology, Erasmus University Medical center, Rotterdam, The Netherlands., Yang X; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Middlesex, UK., Zhao W; Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., de Andrade M; Division of Biomedical Statistics and Informatics, Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, USA., de Vries PS; Department of Epidemiology, Erasmus University Medical center, Rotterdam, The Netherlands., van Zuydam NR; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Medical Research Institute, University of Dundee, Dundee, UK., Anand SS; Population Health Research Institute, Hamilton Health Sciences, Department of Medicine, McMaster University, Hamilton, Ontario, Canada., Bertram L; Platform for Genome Analytics, Institutes of Neurogenetics & Integrative and Experimental Genomics, University of Lübeck, Lübeck, Germany.; Neuroepidemiology and Ageing Research Unit, School of Public Health, Faculty of Medicine, The Imperial College of Science, Technology, and Medicine, London, UK., Beutner F; LIFE Research Center of Civilization Diseases, Leipzig, Germany.; Heart Center Leipzig, Cardiology, University of Leipzig, Leipzig, Germany., Dedoussis G; Department of Dietetics-Nutrition, Harokopio University, Athens, Greece., Frossard P; Center for Non-Communicable Diseases, Karachi, Pakistan., Gauguier D; INSERM, UMRS1138, Centre de Recherche des Cordeliers, Paris, France., Goodall AH; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK.; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK., Gottesman O; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., Haber M; Lebanese American University, School of Medicine, Beirut, Lebanon., Han BG; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Korea., Huang J; Hypertension Division, Fuwai Hospital, National Center For Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Jalilzadeh S; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Kessler T; Deutsches Herzzentrum München, Technische Universität München, München, Germany.; Klinikum rechts der Isar, München, Germany., König IR; DZHK (German Research Center for Cardiovascular Research) partner site Hamburg-Lübeck-Kiel, Lübeck, Germany.; Institut für Medizinische Biometrie und Statistik, Universität zu Lübeck, Lübeck, Germany., Lannfelt L; Department of Public Health and Caring Sciences, Geriatrics, Uppsala University, Uppsala, Sweden., Lieb W; Institut für Epidemiologie, Christian-Albrechts Universität zu Kiel, Kiel, Germany., Lind L; Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Uppsala, Sweden., Lindgren CM; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA., Lokki ML; Transplantation Laboratory, Haartman Institute, University of Helsinki, Helsinki, Finland., Magnusson PK; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Mallick NH; Punjab Institute of Cardiology, Lahore, Pakistan., Mehra N; All India Institute of Medical Sciences, New Delhi, India., Meitinger T; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany.; Institut für Humangenetik, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, München, Germany., Memon FU; Red Crescent Institute of Cardiology, Hyderabad, Pakistan., Morris AP; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Department of Biostatistics, University of Liverpool, Liverpool, UK., Nieminen MS; Department of Medicine, Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland., Pedersen NL; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden., Peters A; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München, German Research Center for Environmental Health, Neuherberg, Germany., Rallidis LS; Second Department of Cardiology, Attikon Hospital, School of Medicine, University of Athens, Athens, Greece., Rasheed A; Center for Non-Communicable Diseases, Karachi, Pakistan.; Red Crescent Institute of Cardiology, Hyderabad, Pakistan., Samuel M; Center for Non-Communicable Diseases, Karachi, Pakistan., Shah SH; Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA., Sinisalo J; Department of Medicine, Department of Cardiology, Helsinki University Central Hospital, Helsinki, Finland., Stirrups KE; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Department of Haematology, University of Cambridge, Cambridge, UK., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, The Netherlands., Wang L; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.; National Human Genome Center at Beijing, Beijing, China., Zaman KS; National Institue of Cardiovascular Diseases, Karachi, Pakistan., Ardissino D; Division of Cardiology, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy.; Associazione per lo Studio della Trombosi in Cardiologia, Pavia, Italy., Boerwinkle E; Human Genetics Center, School of Public Health, The University of Texas Health Science Center at Houston, Houston, Texas, USA.; Human Genome Sequencing Center, Baylor College of Medicine, Houston, Texas, USA., Borecki IB; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Bottinger EP; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., Buring JE; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Department of Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK., Collins R; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Cupples LA; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts, USA., Danesh J; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK., Demuth I; The Berlin Aging Study II; Research Group on Geriatrics; Charité - Universitätsmedizin Berlin, Berlin, Germany.; Institute of Medical and Human Genetics, Charité - Universitätsmedizin Berlin, Berlin, Germany., Elosua R; Grupo de Epidemiología y Genética Cardiovascular, Institut Hospital del Mar d'Investigacions Mèdiques (IMIM), Barcelona, Spain., Epstein SE; MedStar Heart and Vascular Institute, MedStar Washington Hospital Center, Washington, DC, USA., Esko T; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology and Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA., Feitosa MF; Department of Genetics, Washington University School of Medicine, St. Louis, Missouri, USA., Franco OH; Department of Epidemiology, Erasmus University Medical center, Rotterdam, The Netherlands., Franzosi MG; Department of Cardiovascular Research, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milano, Italy., Granger CB; Department of Medicine, Duke University Medical Center, Durham, North Carolina, USA., Gu D; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center of Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Gudnason V; Icelandic Heart Association, Kopavogur, Iceland.; Faculty of Medicine, University of Iceland, Reykjavik, Iceland., Hall AS; Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK., Hamsten A; Cardiovascular Genetics and Genomics Group, Atherosclerosis Research Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden., Harris TB; Laboratory of Epidemiology, Demography, and Biometry, National Institute on Aging, National Institutes of Health, Bethesda, Maryland, USA., Hazen SL; Cleveland Clinic, Cleveland, Ohio, USA., Hengstenberg C; Deutsches Herzzentrum München, Technische Universität München, München, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany., Hofman A; Department of Epidemiology, Erasmus University Medical center, Rotterdam, The Netherlands., Ingelsson E; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Molecular Epidemiology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.; Science for Life Laboratory, Uppsala University, Uppsala, Sweden.; Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California, USA., Iribarren C; Kaiser Permanente Division of Research, Oakland, California, USA., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Durrer Center for Cardiogenetic Research, Amsterdam, The Netherlands.; Interuniversity Cardiology Institute of the Netherlands, Utrecht, The Netherlands., Karhunen PJ; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Forensic Medicine, University of Tampere School of Medicine, Tampere, Finland., Kim BJ; Center for Genome Science, Korea National Institute of Health, Chungcheongbuk-do, Korea., Kooner JS; Department of Cardiology, Ealing Hospital NHS Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.; Cardiovascular Science, National Heart and Lung Institute, Imperial College London, London, UK., Kullo IJ; Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic, Rochester, Minnesota, USA., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Loos RJF; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York, USA.; The Genetics of Obesity and Related Metabolic Traits Program, The Icahn School of Medicine at Mount Sinai, New York, New York, USA.; The Mindich Child Health and Development Institute, The Icahn School of Medicine at Mount Sinai, New York, New York, USA., Melander O; Department of Clinical Sciences, Hypertension and Cardiovascular Disease, Lund University, University Hospital Malmö, Malmö, Sweden., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Institute of Molecular and Cell Biology, University of Tartu, Tartu, Estonia., März W; Vth Department of Medicine (Nephrology, Hypertensiology, Endocrinology, Diabetology, Rheumatology), Medical Faculty of Mannheim, University of Heidelberg, Mannheim, Germany.; Synlab Academy, Synlab Services GmbH, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria., Palmer CN; Medical Research Institute, University of Dundee, Dundee, UK., Perola M; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Department of Health, National Institute for Health and Welfare, Helsinki, Finland.; Institute for Molecular Medicine Finland (FIMM), University of Helsinki, Helsinki, Finland.; Diabetes & Obesity Research Program, University of Helsinki, Helsinki, Finland., Quertermous T; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, California, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, California, USA., Rader DJ; Department of Genetics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Ridker PM; Division of Preventive Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.; Harvard Medical School, Boston, Massachusetts, USA., Ripatti S; Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK.; Department of Public Health, University of Helsinki, Helsinki, Finland.; Institute for Molecular Medicine Finland FIMM, University of Helsinki, Helsinki, Finland., Roberts R; University of Ottawa Heart Institute, Ottawa, Canada., Salomaa V; Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland., Sanghera DK; Department of Pediatrics, College of Medicine, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Department of Pharmaceutical Sciences, College of Pharmacy, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.; Oklahoma Center for Neuroscience, Oklahoma City, Oklahoma, USA., Schwartz SM; Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.; Department of Epidemiology, University of Washington, Seattle, Washington, USA., Seedorf U; Department of Prosthetic Dentistry, Center for Dental and Oral Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Stewart AF; Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Canada., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Thiery J; LIFE Research Center of Civilization Diseases, Leipzig, Germany.; Institute for Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University Hospital Leipzig, Medical Faculty, Leipzig, Germany., Zalloua PA; Lebanese American University, School of Medicine, Beirut, Lebanon.; Harvard School of Public Health, Boston, Massachusetts, USA., O'Donnell CJ; National Heart, Lung, and Blood Institute's Framingham Heart Study, Framingham, Massachusetts, USA.; National Heart, Lung and Blood Institute Division of Intramural Research, Bethesda, Maryland, USA.; Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA., Reilly MP; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Assimes TL; Department of Medicine, Division of Cardiovascular Medicine, Stanford University, Stanford, California, USA.; Stanford Cardiovascular Institute, Stanford University, Stanford, California, USA., Thompson JR; Department of Health Sciences, University of Leicester, Leicester, UK., Erdmann J; Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Lübeck, Germany.; DZHK (German Research Center for Cardiovascular Research) partner site Hamburg-Lübeck-Kiel, Lübeck, Germany., Clarke R; CTSU, Nuffield Department of Population Health, University of Oxford, Oxford, UK., Watkins H; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Kathiresan S; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts, USA.; Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA.; Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA.; Department of Medicine, Harvard Medical School, Boston, Massachusetts, USA., McPherson R; Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Ottawa, Canada., Deloukas P; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia., Schunkert H; Deutsches Herzzentrum München, Technische Universität München, München, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Munich Heart Alliance, München, Germany., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Farrall M; Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.
Publikováno v:
Nature genetics [Nat Genet] 2015 Oct; Vol. 47 (10), pp. 1121-1130. Date of Electronic Publication: 2015 Sep 07.
Autor:
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Nature genetics [Nat Genet] 2013 Jan; Vol. 45 (1), pp. 25-33. Date of Electronic Publication: 2012 Dec 02.
Autor:
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Nature genetics [Nat Genet] 2010 Aug; Vol. 42 (8), pp. 692-7. Date of Electronic Publication: 2010 Jul 11.