Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Yongchan Lee"'
Autor:
Katsuya Takahashi, Yongchan Lee, Angela Fago, Naim M. Bautista, Jay F. Storz, Akihiro Kawamoto, Genji Kurisu, Tomohiro Nishizawa, Jeremy R. H. Tame
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract The principal effect controlling the oxygen affinity of vertebrate haemoglobins (Hbs) is the allosteric switch between R and T forms with relatively high and low oxygen affinity respectively. Uniquely among jawed vertebrates, crocodilians po
Externí odkaz:
https://doaj.org/article/33c62f75f40140c081470ffac962c7cb
Autor:
Yongchan Lee, Outi Haapanen, Anton Altmeyer, Werner Kühlbrandt, Vivek Sharma, Volker Zickermann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Many bacteria employ unique membrane transport systems to survive harsh environmental conditions. Here, authors determined the structure of a cation/proton antiporter at high resolution and studied its mechanism by computer simulations.
Externí odkaz:
https://doaj.org/article/88d63ce2ef994b119a7dfc4e00839e90
Autor:
Yongchan Lee, Pattama Wiriyasermkul, Pornparn Kongpracha, Satomi Moriyama, Deryck J. Mills, Werner Kühlbrandt, Shushi Nagamori
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Cystinuria is caused by mutations in heterodimeric amino acid transporter known as system b0,+. Here, authors discover that Ca2+ stabilizes the interface between two system b0,+ regulatory subunits rBAT, leading to super-dimerization of the b0,+AT–
Externí odkaz:
https://doaj.org/article/e598523dc76944279cc21426e1122f3e
Autor:
Yongchan, Lee, Pattama, Wiriyasermkul, Pornparn, Kongpracha, Satomi, Moriyama, Deryck J, Mills, Werner, Kühlbrandt, Shushi, Nagamori
Publikováno v:
Nature communications. 13(1)
Cystinuria is a genetic disorder characterized by overexcretion of dibasic amino acids and cystine, causing recurrent kidney stones and kidney failure. Mutations of the regulatory glycoprotein rBAT and the amino acid transporter b
Publikováno v:
Nature Communications
SWEET family proteins mediate sugar transport across biological membranes and play crucial roles in plants and animals. The SWEETs and their bacterial homologues, the SemiSWEETs, are related to the PQ-loop family, which is characterized by highly con