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pro vyhledávání: '"Steven Henderson"'
Autor:
Anant A. Agrawal, Enea Salsi, Rakesh Chatrikhi, Steven Henderson, Jermaine L. Jenkins, Michael R. Green, Dmitri N. Ermolenko, Clara L. Kielkopf
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The pre-mRNA splicing factor U2AF65 recognizes 3′ splice sites in human gene transcripts, but the details are not fully understood. Here, the authors report U2AF65 structures and single molecule FRET that reveal mechanistic insights into splice sit
Externí odkaz:
https://doaj.org/article/c1b792d28aba471e81c175eb71e73c9e
Autor:
Enea Salsi, Anant A. Agrawal, Jermaine L. Jenkins, Clara L. Kielkopf, Rakesh Chatrikhi, Steven Henderson, Dmitri N. Ermolenko, Michael R. Green
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Nature Communications
Nature Communications
How the essential pre-mRNA splicing factor U2AF65 recognizes the polypyrimidine (Py) signals of the major class of 3′ splice sites in human gene transcripts remains incompletely understood. We determined four structures of an extended U2AF65–RNA-