Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Palazzo, A."'
Autor:
Pin Lyu, Maria Iribarne, Dmitri Serjanov, Yijie Zhai, Thanh Hoang, Leah J. Campbell, Patrick Boyd, Isabella Palazzo, Mikiko Nagashima, Nicholas J. Silva, Peter F. Hitchcock, Jiang Qian, David R. Hyde, Seth Blackshaw
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Abstract Following acute retinal damage, zebrafish possess the ability to regenerate all neuronal subtypes through Müller glia (MG) reprogramming and asymmetric cell division that produces a multipotent Müller glia-derived neuronal progenitor cell
Externí odkaz:
https://doaj.org/article/71690f1b09a744288c5a191665a5f721
Akademický článek
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Autor:
Roberto Lande, Ernest Y. Lee, Raffaella Palazzo, Barbara Marinari, Immacolata Pietraforte, Giancarlo Santiago Santos, Yves Mattenberger, Francesca Spadaro, Katia Stefanantoni, Nicoletta Iannace, Aleksandra Maria Dufour, Mario Falchi, Manuela Bianco, Elisabetta Botti, Luca Bianchi, Montserrat Alvarez, Valeria Riccieri, Marie-Elise Truchetet, Gerard C.L. Wong, Carlo Chizzolini, Loredana Frasca
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
CXCL4 is an inflammatory chemokine signaling through CXCR3 receptor. Here the authors show a CXCR3-independent function of CXCL4: it forms liquid crystals with DNA, potentiating mammalian and bacterial DNA recognition by TLR9, thereby amplifying inte
Externí odkaz:
https://doaj.org/article/a467d41eb1b041d3bfc13521f62a91e8
Autor:
Fresia Pareja, Alissa H. Brandes, Thais Basili, Pier Selenica, Felipe C. Geyer, Dan Fan, Arnaud Da Cruz Paula, Rahul Kumar, David N. Brown, Rodrigo Gularte-Mérida, Barbara Alemar, Rui Bi, Raymond S. Lim, Ino de Bruijn, Sho Fujisawa, Rui Gardner, Elvin Feng, Anqi Li, Edaise M. da Silva, John R. Lozada, Pedro Blecua, Leona Cohen-Gould, Achim A. Jungbluth, Emad A. Rakha, Ian O. Ellis, Maria I. A. Edelweiss, Juan Palazzo, Larry Norton, Travis Hollmann, Marcia Edelweiss, Brian P. Rubin, Britta Weigelt, Jorge S. Reis-Filho
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Granular cell tumors (GCTs) are rare tumors that arise in multiple anatomical locations. Here, the authors investigate the genomics of GCTs, finding inactivating somatic mutations in ATP6AP1 or ATP6AP2 in 72% of the 82 GCTs analyzed. In vitro manipul
Externí odkaz:
https://doaj.org/article/009968388daa46a8b838d3017e34238c
Autor:
Eleonora Macchia, Kyriaki Manoli, Brigitte Holzer, Cinzia Di Franco, Matteo Ghittorelli, Fabrizio Torricelli, Domenico Alberga, Giuseppe Felice Mangiatordi, Gerardo Palazzo, Gaetano Scamarcio, Luisa Torsi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
The sensing capability of nanometric transducers designed for label-free single molecule detection has been limited by the small number of recognition elements. Here, the authors demonstrate a millimetre-sized field effect transistor capable of selec
Externí odkaz:
https://doaj.org/article/a3fb1f59bcb4472eae23de4a5bfa8193
Autor:
Felipe C. Geyer, Anqi Li, Anastasios D. Papanastasiou, Alison Smith, Pier Selenica, Kathleen A. Burke, Marcia Edelweiss, Huei-Chi Wen, Salvatore Piscuoglio, Anne M. Schultheis, Luciano G. Martelotto, Fresia Pareja, Rahul Kumar, Alissa Brandes, Dan Fan, Thais Basili, Arnaud Da Cruz Paula, John R. Lozada, Pedro Blecua, Simone Muenst, Achim A. Jungbluth, Maria P. Foschini, Hannah Y. Wen, Edi Brogi, Juan Palazzo, Brian P. Rubin, Charlotte K. Y. Ng, Larry Norton, Zsuzsanna Varga, Ian O. Ellis, Emad A. Rakha, Sarat Chandarlapaty, Britta Weigelt, Jorge S. Reis-Filho
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Adenomyoepithelioma is a rare tumor of the breast with an unknown genetic basis. Here the authors perform a genomic analysis of adenomyoepitheliomas revealing that their repertoire of somatic mutations vary according to the estrogen receptor (ER) sta
Externí odkaz:
https://doaj.org/article/542cf17a65664524a59e8d4c4c40fa5e
Autor:
Kahia Messaoudi, Ashfaq Ali, Rameez Ishaq, Alberta Palazzo, Dominika Sliwa, Olivier Bluteau, Sylvie Souquère, Delphine Muller, Khadija M. Diop, Philippe Rameau, Valérie Lapierre, Jean-Pierre Marolleau, Patrick Matthias, Isabelle Godin, Gérard Pierron, Steven G. Thomas, Stephen P. Watson, Nathalie Droin, William Vainchenker, Isabelle Plo, Hana Raslova, Najet Debili
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Histone deacetylase (HDAC) inhibitors, a class of cancer therapeutics, cause thrombocytopenia via an unknown mechanism. Here, the authors show that HDAC6 inhibition impairs proplatelet formation in human megakaryocytes, and show that this is linked t
Externí odkaz:
https://doaj.org/article/e6244d22664d4e168a0d548e8a713d18
Autor:
Brigitte Holzer, Kyriaki Manoli, Gerardo Palazzo, Matteo Ghittorelli, Cinzia Di Franco, Domenico Alberga, Eleonora Macchia, Luisa Torsi, Gaetano Scamarcio, Fabrizio Torricelli, Giuseppe Felice Mangiatordi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)
Nature Communications
Nature communications 9 (2018). doi:10.1038/s41467-018-05235-z
info:cnr-pdr/source/autori:Macchia, Eleonora; Manoli, Kyriaki; Holzer, Brigitte; Di Franco, Cinzia; Ghittorelli, Matteo; Torricelli, Fabrizio; Alberga, Domenico; Mangiatordi, Giuseppe Felice; Palazzo, Gerardo; Scamarcio, Gaetano; Torsi, Luisa/titolo:Single-molecule detection with a millimetre-sized transistor/doi:10.1038%2Fs41467-018-05235-z/rivista:Nature communications/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Nature Communications
Nature communications 9 (2018). doi:10.1038/s41467-018-05235-z
info:cnr-pdr/source/autori:Macchia, Eleonora; Manoli, Kyriaki; Holzer, Brigitte; Di Franco, Cinzia; Ghittorelli, Matteo; Torricelli, Fabrizio; Alberga, Domenico; Mangiatordi, Giuseppe Felice; Palazzo, Gerardo; Scamarcio, Gaetano; Torsi, Luisa/titolo:Single-molecule detection with a millimetre-sized transistor/doi:10.1038%2Fs41467-018-05235-z/rivista:Nature communications/anno:2018/pagina_da:/pagina_a:/intervallo_pagine:/volume:9
Label-free single-molecule detection has been achieved so far by funnelling a large number of ligands into a sequence of single-binding events with few recognition elements host on nanometric transducers. Such approaches are inherently unable to sens
Autor:
Emad A. Rakha, Juan P. Palazzo, Elvin Feng, Pedro Blecua, Ian O. Ellis, Achim A. Jungbluth, Alissa H. Brandes, Pier Selenica, Leona Cohen-Gould, Sho Fujisawa, Rodrigo Gularte-Mérida, Jorge S. Reis-Filho, Anqi Li, Britta Weigelt, Thais Basili, Brian P. Rubin, Rajesh Kumar, Felipe C Geyer, Fresia Pareja, John R. Lozada, Rui Bi, Larry Norton, Barbara Alemar, Travis J. Hollmann, Ino de Bruijn, David N Brown, Edaise M da Silva, Raymond S. Lim, Arnaud Da Cruz Paula, Maria Isabel Albano Edelweiss, Marcia Edelweiss, Dan Fan, Rui Gardner
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Nature Communications
Nature Communications
Granular cell tumors (GCTs) are rare tumors that can arise in multiple anatomical locations, and are characterized by abundant intracytoplasmic granules. The genetic drivers of GCTs are currently unknown. Here, we apply whole-exome sequencing and tar
Autor:
Jean-Pierre Marolleau, Delphine Muller, Dominika Sliwa, Khadija M. Diop, Steven G. Thomas, Gérard Pierron, Alberta Palazzo, Patrick Matthias, Nathalie Droin, Isabelle Godin, Isabelle Plo, Philippe Rameau, Hana Raslova, Sylvie Souquere, Stephen P. Watson, Kahia Messaoudi, Najet Debili, William Vainchenker, Olivier Bluteau, Rameez Ishaq, Ashfaq Ali, Valérie Lapierre
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-17 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, ⟨10.1038/s41467-017-01690-2⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8, ⟨10.1038/s41467-017-01690-2⟩
Thrombocytopenia is a major side effect of a new class of anticancer agents that target histone deacetylase (HDAC). Their mechanism is poorly understood. Here, we show that HDAC6 inhibition and genetic knockdown lead to a strong decrease in human pro