Zobrazeno 1 - 10
of 104
pro vyhledávání: '"P Cooke"'
Autor:
Jessica Knox, Andrew R. Burns, Brittany Cooke, Savina R. Cammalleri, Megan Kitner, Justin Ching, Jack M. P. Castelli, Emily Puumala, Jamie Snider, Emily Koury, J. B. Collins, Salma Geissah, James J. Dowling, Erik C. Andersen, Igor Stagljar, Leah E. Cowen, Mark Lautens, Inga Zasada, Peter J. Roy
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Left unchecked, plant-parasitic nematodes have the potential to devastate crops globally. Highly effective but non-selective nematicides are justifiably being phased-out, leaving farmers with limited options for managing nematode infestation
Externí odkaz:
https://doaj.org/article/609af50dc9664af39474ef0017566555
Autor:
Rob Cooke, Ferran Sayol, Tobias Andermann, Tim M. Blackburn, Manuel J. Steinbauer, Alexandre Antonelli, Søren Faurby
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Birds are among the best-studied animal groups, but their prehistoric diversity is poorly known due to low fossilization potential. Hence, while many human-driven bird extinctions (i.e., extinctions caused directly by human activities such a
Externí odkaz:
https://doaj.org/article/96d0ba76dff042e184dcec5066c1a3cb
Autor:
Christina J. Atchison, Bethan Davies, Emily Cooper, Adam Lound, Matthew Whitaker, Adam Hampshire, Adriana Azor, Christl A. Donnelly, Marc Chadeau-Hyam, Graham S. Cooke, Helen Ward, Paul Elliott
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract The COVID-19 pandemic is having a lasting impact on health and well-being. We compare current self-reported health, quality of life and symptom profiles for people with ongoing symptoms following COVID-19 to those who have never tested posit
Externí odkaz:
https://doaj.org/article/47dd447bfacb4350a0f1ef3faffd497a
Autor:
Cheng Zeng, Jiwei Chen, Emmalee W. Cooke, Arijita Subuddhi, Eliana T. Roodman, Fei Xavier Chen, Kaixiang Cao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract The major enhancer regulator lysine-specific histone demethylase 1A (LSD1) is required for mammalian embryogenesis and is implicated in human congenital diseases and multiple types of cancer; however, the underlying mechanisms remain enigmat
Externí odkaz:
https://doaj.org/article/224b9a5f3c964158b567685eff2fcddd
Autor:
Matthew Whitaker, Bethan Davies, Christina Atchison, Wendy Barclay, Deborah Ashby, Ara Darzi, Steven Riley, Graham Cooke, Christl A. Donnelly, Marc Chadeau-Hyam, Paul Elliott, Helen Ward
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-8 (2023)
Abstract The value of SARS-CoV-2 lateral flow immunoassay (LFIA) tests for estimating individual disease risk is unclear. The REACT-2 study in England, UK, obtained self-administered SARS-CoV-2 LFIA test results from 361,801 adults in January-May 202
Externí odkaz:
https://doaj.org/article/ad355309c57644ea9659226f453e6bc2
Autor:
Jie Lv, Shu Meng, Qilin Gu, Rongbin Zheng, Xinlei Gao, Jun-dae Kim, Min Chen, Bo Xia, Yihan Zuo, Sen Zhu, Dongyu Zhao, Yanqiang Li, Guangyu Wang, Xin Wang, Qingshu Meng, Qi Cao, John P. Cooke, Longhou Fang, Kaifu Chen, Lili Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract A comprehensive understanding of endothelial cell lineage specification will advance cardiovascular regenerative medicine. Recent studies found that unique epigenetic signatures preferentially regulate cell identity genes. We thus systematic
Externí odkaz:
https://doaj.org/article/14928c9950cd4eacb8762efe2e68b9ba
Autor:
Daniel J. Fazakerley, Julian van Gerwen, Kristen C. Cooke, Xiaowen Duan, Elise J. Needham, Alexis Díaz-Vegas, Søren Madsen, Dougall M. Norris, Amber S. Shun-Shion, James R. Krycer, James G. Burchfield, Pengyi Yang, Mark R. Wade, Joseph T. Brozinick, David E. James, Sean J. Humphrey
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-20 (2023)
The failure of metabolic tissues to respond to insulin is an early marker of type 2 diabetes. Here, the authors show, using global phosphoproteomics, that insulin resistance is caused by a marked rewiring of both canonical and non-canonical insulin s
Externí odkaz:
https://doaj.org/article/1d1d85eedd7542a2a8117c06e8ff0883
Autor:
Matthew Whitaker, Joshua Elliott, Barbara Bodinier, Wendy Barclay, Helen Ward, Graham Cooke, Christl A. Donnelly, Marc Chadeau-Hyam, Paul Elliott
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
In this study, the authors assess changing symptom profiles associated with different SARS-CoV-2 variants from May 2020 to March 2022 in England. Using data from the REACT-1 study, they find that Omicron infection is more often associated with cold a
Externí odkaz:
https://doaj.org/article/49ef4a4c20114cb6a6311096e7fa0512
Autor:
Laura J. Grange, John J. Reynolds, Farid Ullah, Bertrand Isidor, Robert F. Shearer, Xenia Latypova, Ryan M. Baxley, Antony W. Oliver, Anil Ganesh, Sophie L. Cooke, Satpal S. Jhujh, Gavin S. McNee, Robert Hollingworth, Martin R. Higgs, Toyoaki Natsume, Tahir Khan, Gabriel Á. Martos-Moreno, Sharon Chupp, Christopher G. Mathew, David Parry, Michael A. Simpson, Nahid Nahavandi, Zafer Yüksel, Mojgan Drasdo, Anja Kron, Petra Vogt, Annemarie Jonasson, Saad Ahmed Seth, Claudia Gonzaga-Jauregui, Karlla W. Brigatti, Alexander P. A. Stegmann, Masato Kanemaki, Dragana Josifova, Yuri Uchiyama, Yukiko Oh, Akira Morimoto, Hitoshi Osaka, Zineb Ammous, Jesús Argente, Naomichi Matsumoto, Constance T.R.M. Stumpel, Alexander M. R. Taylor, Andrew P. Jackson, Anja-Katrin Bielinsky, Niels Mailand, Cedric Le Caignec, Erica E. Davis, Grant S. Stewart
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-22 (2022)
The SMC5/6 complex is critical for genome stability. Here, the authors identify mutations in SLF2 and SMC5 as cause of Atelís Syndrome characterized by microcephaly, short stature, anemia, segmented chromosomes and mosaic variegated hyperploidy.
Externí odkaz:
https://doaj.org/article/bfe3845b80824c5996d10d21e1575e9d
Autor:
Paul Elliott, Oliver Eales, Barbara Bodinier, David Tang, Haowei Wang, Jakob Jonnerby, David Haw, Joshua Elliott, Matthew Whitaker, Caroline E. Walters, Christina Atchison, Peter J. Diggle, Andrew J. Page, Alexander J. Trotter, Deborah Ashby, Wendy Barclay, Graham Taylor, Helen Ward, Ara Darzi, Graham S. Cooke, Marc Chadeau-Hyam, Christl A. Donnelly
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
The REACT-1 study measures the community prevalence of SARS-CoV-2 in England through repeated cross-sectional surveys. Here, the authors present data from REACT-1 that document the increase in infection prevalence, particularly among children, associ
Externí odkaz:
https://doaj.org/article/78e75435823a4949a145e48018f8a797