Zobrazeno 1 - 10
of 75
pro vyhledávání: '"O'Rourke, A. A."'
Autor:
Bryan K. Mignone, Leon Clarke, James A. Edmonds, Angelo Gurgel, Howard J. Herzog, Jeremiah X. Johnson, Dharik S. Mallapragada, Haewon McJeon, Jennifer Morris, Patrick R. O’Rourke, Sergey Paltsev, Steven K. Rose, Daniel C. Steinberg, Aranya Venkatesh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Energy transition scenarios are characterized by increasing electrification and improving efficiency of energy end uses, rapid decarbonization of the electric power sector, and deployment of carbon dioxide removal (CDR) technologies to offse
Externí odkaz:
https://doaj.org/article/ccd60468667640389a2a716a4cf778a7
A standardized metric to enhance clinical trial design and outcome interpretation in type 1 diabetes
Autor:
Alyssa Ylescupidez, Henry T. Bahnson, Colin O’Rourke, Sandra Lord, Cate Speake, Carla J. Greenbaum
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The use of a standardized outcome metric enhances clinical trial interpretation and cross-trial comparison. If a disease course is predictable, comparing modeled predictions with outcome data affords the precision and confidence needed to ac
Externí odkaz:
https://doaj.org/article/bd672434f5da493f97ffb6f6a8e89aca
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Recent experimental advances have stimulated interest in the use of large, two-dimensional arrays of Rydberg atoms as a platform for quantum information processing and to study exotic many-body quantum states. However, the native long-range
Externí odkaz:
https://doaj.org/article/89f57a2d7bd44dfcb4a684eec7fc16e2
Akademický článek
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Autor:
Karin D. Prummel, Helena L. Crowell, Susan Nieuwenhuize, Eline C. Brombacher, Stephan Daetwyler, Charlotte Soneson, Jelena Kresoja-Rakic, Agnese Kocere, Manuel Ronner, Alexander Ernst, Zahra Labbaf, David E. Clouthier, Anthony B. Firulli, Héctor Sánchez-Iranzo, Sundar R. Naganathan, Rebecca O’Rourke, Erez Raz, Nadia Mercader, Alexa Burger, Emanuela Felley-Bosco, Jan Huisken, Mark D. Robinson, Christian Mosimann
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
The mesothelium supports homeostasis and regeneration, yet its development origins remain unclear. Here, the authors uncovered the earliest mesothelium progenitor cells in zebrafish, linking Hand2 gene function to mesothelium formation and its re-act
Externí odkaz:
https://doaj.org/article/445f40166b9345a1905f77ae35cd17f3
Autor:
Richard Border, Sean O’Rourke, Teresa de Candia, Michael E. Goddard, Peter M. Visscher, Loic Yengo, Matt Jones, Matthew C. Keller
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Methods for estimating heritability, the fraction of variance attributable to genetic factors, assume random mating. Here, the authors show that under assortative mating, when mate choice reflects phenotypic similarity, these methods produce overesti
Externí odkaz:
https://doaj.org/article/df9f8cc80d744a7aa180f73386063991
Small Cajal body-associated RNA 2 (scaRNA2) regulates DNA repair pathway choice by inhibiting DNA-PK
Autor:
Sofie Bergstrand, Eleanor M. O’Brien, Christos Coucoravas, Dominika Hrossova, Dimitra Peirasmaki, Sandro Schmidli, Soniya Dhanjal, Chiara Pederiva, Lee Siggens, Oliver Mortusewicz, Julienne J. O’Rourke, Marianne Farnebo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Proper repair of DNA double-strand breaks is essential for genomic stability. Here, the authors report that a long non-coding RNA, scaRNA2, inhibits DNA-PK and thereby regulates the choice between error-prone NHEJ and error-free HR DNA repair.
Externí odkaz:
https://doaj.org/article/d2933dc7f92146b8a26cfc567c940465
Autor:
Yang Ou, Christopher Roney, Jameel Alsalam, Katherine Calvin, Jared Creason, Jae Edmonds, Allen A. Fawcett, Page Kyle, Kanishka Narayan, Patrick O’Rourke, Pralit Patel, Shaun Ragnauth, Steven J. Smith, Haewon McJeon
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Stabilizing climate change requires simultaneous mitigation of all greenhouse gas emissions (GHGs). Here the authors examine 90 mitigation scenarios pairing different levels of CO2 and non-CO2 GHG abatement pathways to demonstrate the contributions o
Externí odkaz:
https://doaj.org/article/bc9db4a296924c219293c9b42aea6209
Autor:
Erin E. McDuffie, Randall V. Martin, Joseph V. Spadaro, Richard Burnett, Steven J. Smith, Patrick O’Rourke, Melanie S. Hammer, Aaron van Donkelaar, Liam Bindle, Viral Shah, Lyatt Jaeglé, Gan Luo, Fangqun Yu, Jamiu A. Adeniran, Jintai Lin, Michael Brauer
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Ambient fine particulate matter (PM2.5) is one of the most important environmental health risk factors in many regions. Here, the authors present an assessment of PM2.5 emission sources and the related health impacts across global to sub-national sca
Externí odkaz:
https://doaj.org/article/af996bbbd53c4f399c3f4d36e2ff9bf4
Akademický článek
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