Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Nan Song"'
Autor:
Dongliang Bian, Liangdong Sun, Junjie Hu, Liang Duan, Haoran Xia, Xinsheng Zhu, Fenghuan Sun, Lele Zhang, Huansha Yu, Yicheng Xiong, Zhida Huang, Deping Zhao, Nan Song, Jie Yang, Xiao Bao, Wei Wu, Jie Huang, Wenxin He, Yuming Zhu, Gening Jiang, Peng Zhang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract Afatinib, an irreversible ErbB-family blocker, could improve the survival of advanced epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer patients (NSCLCm+). This phase II trial (NCT04201756) aimed to assess the feasibi
Externí odkaz:
https://doaj.org/article/66ace9c1807645d998c254ed49e8d3df
Autor:
Shangda Yang, Ling Liu, Cheng Cao, Nan Song, Yuejiao Wang, Shuai Ma, Qi Zhang, Na Yu, Xiang Ding, Fuquan Yang, Shanshan Tian, Kai Zhang, Tao Sun, Jie Yang, Zhi Yao, Shaoyuan Wu, Lei Shi
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Histone chaperone ASF1A is often dysregulated in cancers, however the regulation of its abundance is unclear. Here, the authors show that USP52 promotes ASF1A stability through deubiquitination while impairment of this stability reduces breast tumori
Externí odkaz:
https://doaj.org/article/19657680f5d0410bbe493e8461cbd273
Autor:
Xin Li, Nan Song, Ling Liu, Xinhua Liu, Xiang Ding, Xin Song, Shangda Yang, Lin Shan, Xing Zhou, Dongxue Su, Yue Wang, Qi Zhang, Cheng Cao, Shuai Ma, Na Yu, Fuquan Yang, Yan Wang, Zhi Yao, Yongfeng Shang, Lei Shi
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
USP9X is a deubiquitinating enzyme with many known substrates and functions; it has been linked to cancer but the mechanisms remain unclear. Here Liet al. report that USP9X stabilizes the centrosomal protein CEP131 leading to centrosome amplification
Externí odkaz:
https://doaj.org/article/6cceee600b164ac2aaf2e9cf578a0b1a
Autor:
Shuai Ma, Zhang Qi, Tao Sun, Zhi Yao, Fuquan Yang, Shaoyuan Wu, Kai Zhang, Na Yu, Cheng Cao, Shanshan Tian, Yuejiao Wang, Lei Shi, Xiang Ding, Shangda Yang, Jie Yang, Nan Song, Ling Liu
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Nature Communications, Vol 9, Iss 1, Pp 1-17 (2018)
Histone chaperone ASF1A has been reported to be dysregulated in multiple tumors; however, the underlying molecular mechanism that how the abundance and function of ASF1A are regulated remains unclear. Here we report that ASF1A is physically associate
Autor:
Na Yu, Xin Song, Shuai Ma, Zhi Yao, Yongfeng Shang, Xing Zhou, Fuquan Yang, Nan Song, Lin Shan, Cheng Cao, Shangda Yang, Dongxue Su, Lei Shi, Ling Liu, Xiang Ding, Zhang Qi, Xin Li, Xinhua Liu, Yan Wang, Yue Wang
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
Defective centrosome duplication is implicated in microcephaly and primordial dwarfism as well as various ciliopathies and cancers. Yet, how the centrosome biogenesis is regulated remains poorly understood. Here we report that the X-linked deubiquiti