Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael L. Gross"'
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
The intrinsic flexibility of membranes proteins still poses a challenge in determining their active structure. Here the authors describe the development of a method that combines chemical footprinting and mass spectrometry to assist in determining th
Externí odkaz:
https://doaj.org/article/79f9a105291b4eca88c2f9f488f9ee6d
Autor:
Qianglin Fang, Dongjie Zhu, Irina Agarkova, Jagat Adhikari, Thomas Klose, Yue Liu, Zhenguo Chen, Yingyuan Sun, Michael L. Gross, James L. Van Etten, Xinzheng Zhang, Michael G. Rossmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nucleocytoplasmic large DNA viruses are a group of viruses that infect many eukaryotic hosts. Here, the authors provide a 3.5 Å resolution icosahedrally-averaged capsid structure of Paramecium bursaria chlorella virus 1 and show how 1800 minor capsi
Externí odkaz:
https://doaj.org/article/957b37d27371401a819badbfcede8eec
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Expression of TEM β-lactamase is a predominant mechanism underlying antibiotic resistance in pathogenic Gram-negative bacteria. Here, the authors use Markov state models to reveal and experimentally confirm hidden conformations that determine TEM su
Externí odkaz:
https://doaj.org/article/234708999b6a401a85bad9993edf6cfe
Autor:
Xinzheng Zhang, Irina V. Agarkova, Jagat Adhikari, James L. Van Etten, Yue Liu, Michael L. Gross, Zhenguo Chen, Dongjie Zhu, Yingyuan Sun, Thomas Klose, Michael G. Rossmann, Qianglin Fang
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Although the nucleocytoplasmic large DNA viruses (NCLDVs) are one of the largest group of viruses that infect many eukaryotic hosts, the near-atomic resolution structures of these viruses have remained unknown. Here we describe a 3.5 Å resolution ic
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Nature Communications
Nature Communications
TEM β-lactamase confers bacteria with resistance to many antibiotics and rapidly evolves activity against new drugs. However, functional changes are not easily explained by differences in crystal structures. We employ Markov state models to identify