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Autor:
Teumer A; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany. ateumer@uni-greifswald.de.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany. ateumer@uni-greifswald.de., Chaker L; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Groeneweg S; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Li Y; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Di Munno C; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Science and Technologies, University of Sannio, Benevento, Italy., Barbieri C; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Schultheiss UT; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Ahluwalia TS; Steno Diabetes Center Copenhagen, Gentofte, Denmark.; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Akiyama M; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Appel EVR; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Arking DE; McKusick-Nathans Institute of Genetic Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA., Arnold A; Department of Biostatistics, University of Washington, Seattle, WA, USA., Astrup A; Department of Nutrition, Exercise, and Sports, Faculty of Science, University of Copenhagen, Copenhagen, Denmark., Beekman M; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Beilby JP; Pathwest Laboratory Medicine WA, Nedlands, WA, 6009, Australia.; School of Biomedical Sciences, University of Western Australia, Crawley, WA, 6009, Australia., Bekaert S; Bimetra, Clinical Research Center Ghent, Ghent University Hospital, Ghent, Belgium., Boerwinkle E; Human Genetics Center, University of Texas Health Science Center, 1200 Pressler Street, Houston, TX, 77030, USA., Brown SJ; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia., De Buyzere M; Department of Cardiology, Ghent University Hospital, Ghent, Belgium., Campbell PJ; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia., Ceresini G; Department of Medicine and Surgery, University of Parma, University Hospital of Parma, Parma, Italy., Cerqueira C; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark., Cucca F; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.; Dipartimento di Scienze Biomediche, Università degli Studi di Sassari, Sassari, Italy., Deary IJ; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Deelen J; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.; Max Planck Institute for Biology of Ageing, Cologne, Germany., Eckardt KU; Department of Nephrology and Hypertension, University of Erlangen-Nürnberg, Erlangen, Germany.; Department of Nephrology and Medical Intensive Care, Charité - Universitätsmedizin Berlin, Berlin, Germany., Ekici AB; Institute of Human Genetics, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany., Eriksson JG; Department of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.; Folkhälsan Research Center, Helsinki, Finland.; National Institute for Health and Welfare, Helsinki, Finland., Ferrrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Fiers T; Department of Clinical Chemistry, Ghent University Hospital, Ghent, Belgium., Fiorillo E; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy., Ford I; Robertson Centre for Biostatistics, University of Glasgow, Glasgow, UK., Fox CS; National Heart, Lung, and Blood Institute's Framingham Heart Study and the Center for Population Studies, Framingham, MA, USA.; Division of Endocrinology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Fuchsberger C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Galesloot TE; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Gieger C; Helmholtz Zentrum München, Institute of Epidemiology, German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, German Research Centre for Environmental Health, Neuherberg, Germany., Gögele M; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., De Grandi A; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Greiser KH; German Research Centre Division of Cancer Epidemiology, Heidelberg, Germany., Haljas K; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Harris SE; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and MRC Institute of Genetics and Molecular Medicine, Edinburgh, UK., van Heemst D; Leiden University Medical Center, Geriatrics and Gerontology, Leiden, The Netherlands., den Heijer M; Vrije Universiteit Medisch Centrum, Amsterdam, The Netherlands., Hicks AA; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., den Hollander W; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Homuth G; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, Greifswald, Germany., Hui J; Pathwest Laboratory Medicine WA, Nedlands, WA, 6009, Australia.; Medical School, University of Western Australia, Crawley, WA, 6009, Australia., Ikram MA; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands., Ittermann T; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Jensen RA; Department of Medicine, Cardiovascular Health Research Unit, University of Washington, Seattle, WA, USA., Jing J; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.; Faculty of Biology, University of Freiburg, Freiburg, Germany., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands.; Einthoven Laboratory for Experimental Vascular Medicine, LUMC, Leiden, The Netherlands., Kajantie E; National Institute for Health and Welfare, Helsinki, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.; PEDEGO Research Unit, MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Kamatani Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Kasbohm E; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; Institute of Epidemiology, Friedrich-Loeffler-Institut (FLI), Federal Research Institute for Animal Health, Greifswald, Germany., Kaufman JM; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Kiemeney LA; Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands., Kloppenburg M; Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands.; Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Kronenberg F; Department of Medical Genetics, Division of Genetic Epidemiology, Molecular and Clinical Pharmacology, Medical University of Innsbruck, Innsbruck, Austria., Kubo M; Laboratory for Genotyping Development, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan., Lahti J; Department of Psychology and Logopedics, Faculty of Medicine, University of Helsinki, Helsinki, Finland., Lapauw B; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Li S; Department of Biostatistics, Boston University, Boston, MA, USA., Liewald DCM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Lim EM; Pathwest Laboratory Medicine WA, Nedlands, WA, 6009, Australia.; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia., Linneberg A; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark., Marina M; Department of Medicine and Surgery, University of Parma, University Hospital of Parma, Parma, Italy., Mascalzoni D; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Matsuda K; Department of Computational Biology, Graduate School of Frontier Sciences, The University of Tokyo, Tokyo, Japan., Medenwald D; Institute for Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Meisinger C; Helmholtz Zentrum München, Institute of Epidemiology, German Research Center for Environmental Health, Neuherberg, Germany.; Chair of Epidemiology, Ludwig-Maximilians-Universität München, at UNIKA-T Augsburg, Augsburg, Germany., Meulenbelt I; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., De Meyer T; Department of Data Analysis and Mathematical Modelling, Ghent University, Ghent, Belgium., Meyer Zu Schwabedissen HE; Department of Pharmaceutical Sciences, University of Basel, Basel, Switzerland., Mikolajczyk R; Institute for Medical Epidemiology, Biostatistics and Informatics, Martin-Luther-University Halle-Wittenberg, Halle, Germany., Moed M; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Netea-Maier RT; Department of Internal Medicine, Division of Endocrinology, Radboud University Medical Center, Nijmegen, The Netherlands., Nolte IM; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Okada Y; Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan.; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Osaka, Japan.; Laboratory of Statistical Immunology, Immunology Frontier Research Center (WPI-IFReC), Osaka University, Suita, Japan., Pala M; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy., Pattaro C; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Petersmann A; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, Greifswald, Germany., Porcu E; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.; Center for Integrative Genomics, University of Lausanne, and Swiss Institute of Bioinformatics, 1015, Lausanne, Switzerland., Postmus I; Department of Internal Medicine, Section of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, Netherlands., Pramstaller PP; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Psaty BM; Cardiovascular Health Research Unit, Departments of Medicine, Epidemiology and Health Services, University of Washington, Seattle, WA, USA.; Kaiser Permanente Washington Health Research Institute, Seattle, WA, USA., Ramos YFM; Department of Biomedical Data Sciences, Section of Molecular Epidemiology, Leiden University Medical Center, Leiden, The Netherlands., Rawal R; Helmholtz Zentrum München, Institute of Epidemiology, German Research Center for Environmental Health, Neuherberg, Germany., Redmond P; Department of Psychology, University of Edinburgh, Edinburgh, UK., Richards JB; Lady Davis Institute, Jewish General Hospital, Montreal, QC, H3T 1E2, Canada.; The Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Campus, Lambeth Palace Road, London, SE1 7EH, UK., Rietzschel ER; Biobanking and Cardiovascular Epidemiology, Ghent University Hospital, Ghent, Belgium.; Department of Internal Medicine (Cardiology), Ghent University, Ghent, Belgium., Rivadeneira F; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Roef G; Department of Endocrinology, Ghent University Hospital, Ghent, Belgium., Rotter JI; The Institute for Translational Genomics and Population Sciences, Departments of Pediatrics and Medicine, LABioMed at Harbor-UCLA Medical Center, Torrance, CA, USA., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Schlessinger D; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA., Selvin E; Department of Epidemiology, Welch Center for Prevention, Epidemiology and Clinical Research, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA., Slagboom PE; Molecular Epidemiology, Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Soranzo N; The Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, CB10 1HH, UK., Sørensen TIA; Novo Nordisk Foundation Center for Basic Metabolic Research, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Department of Public Health (Section on Epidemiology), Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spector TD; The Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Campus, Lambeth Palace Road, London, SE1 7EH, UK., Starr JM; Centre for Cognitive Ageing and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Taes Y; AZ Sint Jan Brugge, Brugge, Belgium., Taliun D; Institute for Biomedicine, Eurac Research, Affiliated Institute of the University of Lubeck, Bolzano, Italy., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, MD, USA., Thuesen B; Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, The Capital Region, Copenhagen, Denmark., Tiller D; Chair of Epidemiology, Ludwig-Maximilians-Universität München, at UNIKA-T Augsburg, Augsburg, Germany., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Uitterlinden AG; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Visser WE; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Walsh JP; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.; Medical School, University of Western Australia, Crawley, WA, 6009, Australia., Wilson SG; Department of Endocrinology and Diabetes, Sir Charles Gairdner Hospital, Nedlands, WA, 6009, Australia.; Medical School, University of Western Australia, Crawley, WA, 6009, Australia.; The Department of Twin Research and Genetic Epidemiology, King's College London, St. Thomas' Campus, Lambeth Palace Road, London, SE1 7EH, UK., Wolffenbuttel BHR; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Yang Q; Department of Biostatistics, Boston University, Boston, MA, USA., Zheng HF; Diseases & Population (DaP) Geninfo Lab, School of Life Sciences, Westlake University and Westlake Institute for Advanced Study, Hangzhou, Zhejiang, China.; Institute of Aging Research and the Affiliated Hospital, School of Medicine, Hangzhou Normal University, Hangzhou, Zhejiang, China., Cappola A; Division of Endocrinology, Diabetes, and Metabolism, University of Pennsylvania School of Medicine, Philadelphia, PA, USA., Peeters RP; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Naitza S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy., Völzke H; Institute for Community Medicine, University Medicine Greifswald, Greifswald, Germany.; DZHK (German Center for Cardiovascular Research), Partner Site Greifswald, Greifswald, Germany., Sanna S; Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato, Monserrato, Italy.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Köttgen A; Department of Biometry, Epidemiology and Medical Bioinformatics, Institute of Genetic Epidemiology, Faculty of Medicine and Medical Center-University of Freiburg, Freiburg, Germany.; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, 625 N Wolfe Street, Baltimore, MD, 21205, USA., Visser TJ; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Medici M; Erasmus MC Academic Center for Thyroid Diseases, Rotterdam, The Netherlands.; Department of Epidemiology, Erasmus Medical Center, Rotterdam, The Netherlands.; Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands.
Publikováno v:
Nature communications [Nat Commun] 2018 Oct 26; Vol. 9 (1), pp. 4455. Date of Electronic Publication: 2018 Oct 26.
Autor:
Lu Y; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Day FR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Gustafsson S; Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden., Buchkovich ML; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Na J; Department of Developmental and Regenerative Biology, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Bataille V; West Herts NHS Trust, Herts HP2 4AD, UK.; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Cousminer DL; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Dastani Z; Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Esko T; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA., Evans DM; University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland 4102, Australia.; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Falchi M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK., Feitosa MF; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA., Ferreira T; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Hedman ÅK; Science for Life Laboratory, Uppsala University, 750 85 Uppsala, Sweden.; Department of Medical Sciences, Molecular Epidemiology, Uppsala University, 751 85 Uppsala, Sweden.; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Haring R; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; European University of Applied Sciences, Faculty of Applied Public Health, 18055 Rostock, Germany., Hysi PG; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Iles MM; Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK., Justice AE; Department of Epidemiology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA., Kanoni S; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK., Lagou V; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Li R; Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Li X; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Locke A; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Lu C; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Mägi R; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia., Perry JR; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Pers TH; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge 02142, USA.; Department of Epidemiology Research, Statens Serum Institut, 2100 Copenhagen, Denmark., Qi Q; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., Sanna M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK.; Department of Genomics of Common Disease, School of Public Health, Imperial College London, London W12 0NN, UK., Schmidt EM; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Shungin D; Lund University Diabetes Centre, Department of Clinical Science, Genetic and Molecular Epidemiology Unit, Skåne University Hosptial, 205 02 Malmö, Sweden.; Department of Public Health and Clinical Medicine, Unit of Medicine, Umeå University, 901 87 Umeå, Sweden.; Department of Odontology, Umeå University, 901 85 Umeå, Sweden., Teumer A; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; Interfaculty Institute for Genetics and Functional Genomics, University Medicine Greifswald, 17475 Greifswald, Germany., Vinkhuyzen AA; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia., Walker RW; The Charles Bronfman Institute for Personalized Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; The Department of Preventive Medicine, The Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Westra HJ; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Divisions of Genetics and Rheumatology, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02446, USA.; Partners Center for Personalized Genetic Medicine, Boston, Massachusetts 02446, USA., Zhang M; Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Zhao JH; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Zhu Z; Queensland Brain Institute, The University of Queensland, Brisbane 4072, Australia., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Ahluwalia TS; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sceinces, University of Copenhagen, 2200 Copenhagen, Denmark.; Danish Pediatric Asthma Center, Gentofte Hospital, The Capital Region, 2200 Copenhagen, Denmark.; Steno Diabetes Center A/S, DK-2820 Gentofte, Denmark., Bakker SJ; University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands., Bellis C; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Bonnefond A; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Borodulin K; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Buchman AS; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Cederholm T; Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism, Uppsala University, 751 85 Uppsala, Sweden., Choh AC; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Choi HJ; Department of Anatomy, Seoul National University College of Medicine, Seoul 03080, Korea., Curran JE; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520., de Groot LC; Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands., De Jager PL; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Harvard Medical School, Boston, Massachusetts 02115, USA.; Program in Translational NeuroPsychiatric Genomics, Department of Neurology, Brigham and Women's Hospital, Boston, Massachusetts 02115, USA., Dhonukshe-Rutten RA; Department of Human Nutrition, Wageningen University, 6700 EV Wageningen, The Netherlands., Enneman AW; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Eury E; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Evans DS; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Forsen T; Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland., Friedrich N; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Fumeron F; INSERM, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Sorbonne Universités, UPMC Univ Paris 06, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Université Paris Descartes, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France.; Univ Paris Diderot, Sorbonne Paris Cité, UMR_S 1138, Centre de Recherche des Cordeliers, F-75006 Paris, France., Garcia ME; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA., Gärtner S; Department of Medicine A, University Medicine Greifswald, 17475 Greifswald, Germany., Han BG; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea., Havulinna AS; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hayward C; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Hernandez D; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA., Hillege H; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Ittermann T; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany., Kent JW; Department of Genetics, Texas Biomedical Research Institute, San Antonio, Texas 78245, USA., Kolcic I; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia., Laatikainen T; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Hospital District of North Karelia, FI-80210 Joensuu, Finland.; Institute of Public Health and Clinical Nutrition, University of Eastern Finland, FI-70211 Kuopio, Finland., Lahti J; Folkhälsan Research Centre, FI-00290 Helsinki, Finland.; Institute of Behavioural Sciences, University of Helsinki, FI-00014 Helsinki, Finland., Mateo Leach I; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Lee CG; Department of Medicine, Oregon Health and Science University, Portland, Oregon 97239, USA.; Research Service, Veterans Affairs Medical Center, Portland, Oregon 97239, USA., Lee JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do 370914, Korea., Liu T; Max Planck Institute for Molecular Genetics, Department of Vertebrate Genomics, 14195 Berlin, Germany.; Max Planck Institute for Human Development, 14194 Berlin, Germany., Liu Y; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA., Lobbens S; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Loh M; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Translational Laboratory in Genetic Medicine (TLGM), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos, Level 5, Singapore 138648, Singapore., Lyytikäinen LP; Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland., Medina-Gomez C; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Michaëlsson K; Department of Surgical Sciences, Orthopedics, Uppsala University, 751 85 Uppsala, Sweden., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health, Bethesda, Maryland 20892, USA., Nielson CM; School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Oozageer L; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK., Pascoe L; Institute of Cell &Molecular Biosciences, Newcastle University, Newcastle NE1 7RU, UK., Paternoster L; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Polašek O; Department of Public Health, Faculty of Medicine, University of Split, Split 21000, Croatia.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Ripatti S; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland., Sarzynski MA; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Shin CS; Department of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Korea., Narančić NS; Institute for Anthropological Research, Zagreb 10000, Croatia., Spira D; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Srikanth P; School of Public Health, Oregon Health &Science University, Portland, Oregon 97239, USA.; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Steinhagen-Thiessen E; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Lipid Clinic at the Interdisciplinary Metabolism Center, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Sung YJ; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA., Swart KM; EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.; VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands., Taittonen L; Department of Pediatrics, University of Oulu, FI-90014 Oulu, Finland.; Department of Pediatrics, Vaasa Central Hospital, FI-65100 Vaasa, Finland., Tanaka T; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Tikkanen E; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Hjelt Institute, University of Helsinki, FI-00014 Helsinki, Finland., van der Velde N; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., van Schoor NM; EMGO Institute for Health and Care Research, VU University Medical Center, 1081 BT Amsterdam, The Netherlands.; VUMC, Department of Epidemiology and Biostatistics, 1081 BT Amsterdam, The Netherlands., Verweij N; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands., Wright AF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Yu L; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Zmuda JM; Department of Epidemiology; University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA., Eklund N; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Forrester T; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Grarup N; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Jackson AU; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Kristiansson K; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kuulasmaa T; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland., Kuusisto J; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Kuopio University Hospital, 70029 Kuopio, Finland., Lichtner P; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Luan J; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Männistö S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Palmer CD; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Divisions of Endocrinology and Genetics and Center for Basic and Translational Obesity Research, Boston Children's Hospital, Boston, Massachusetts 02115, USA., Ried JS; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Scott RA; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Stancáková A; Department of Medicine, University of Eastern Finland and Kuopio University Hospital, 70210 Kuopio, Finland., Wagner PJ; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Demirkan A; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Döring A; Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Gudnason V; Icelandic Heart Association, Kopavogur 201, Iceland.; University of Iceland, Faculty of Medicine, Reykjavik 101, Iceland., Kiel DP; Department of Medicine Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02115.; Institute for Aging Research Hebrew Senior Life, Boston, Massachusetts 02131, USA., Kühnel B; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Mangino M; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Mcknight B; Cardiovascular Health Research Unit, University of Washington, Seattle, Washington 98101, USA.; Program in Biostatistics and Biomathematics, Divison of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.; Department of Biostatistics, University of Washington, Seattle, Washington 98195, USA., Menni C; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., O'Connell JR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA., Oostra BA; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands., Shuldiner AR; Program for Personalized and Genomic Medicine, Division of Endocrinology, Diabetes and Nutrition, Department of Medicine, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA.; Geriatric Research and Education Clinical Center, Vetrans Administration Medical Center, Baltimore, Maryland 21042, USA., Song K; Genetics, Projects Clinical Platforms and Sciences, GlaxoSmithKline, Philadelphia, Pennsylvania 19112, USA., Vandenput L; Centre for Bone and Arthritis Research, Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, 413 45 Gothenburg, Sweden., van Duijn CM; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Genetic Epidemiology Unit, Department of Epidemiology, Erasmus University Medical Center, 3015GE Rotterdam, The Netherlands.; Center for Medical Systems Biology, 2300 Leiden, The Netherlands., Vollenweider P; Department of Internal Medicine, University Hospital Lausanne (CHUV) and University of Lausanne, 1011 Lausanne, Switzerland., White CC; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA., Boehnke M; Center for Statistical Genetics, Department of Biostatistics, University of Michigan, Ann Arbor, Michigan 48109, USA., Boettcher Y; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Cooper RS; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Forouhi NG; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Gieger C; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Grallert H; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany., Hingorani A; Institute of Cardiovascular Science, University College London, London WC1E 6BT, UK., Jørgensen T; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, 2200 Copenhagen, Denmark.; Faculty of Medicine, University of Aalborg, 9220 Aalborg, Denmark.; Research Centre for Prevention and Health, DK2600 Capital Region of Denmark, Denmark., Jousilahti P; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kivimaki M; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Kumari M; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Laakso M; Faculty of Health Sciences, Institute of Clinical Medicine, Internal Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Department of Medicine, University of Eastern Finland, 70210 Kuopio, Finland.; Kuopio University Hospital, 70029 Kuopio, Finland., Langenberg C; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK.; Department of Epidemiology and Public Health, UCL, London WC1E 6BT, UK., Linneberg A; Research Centre for Prevention and Health, Glostrup Hospital, 2600 Glostrup, Denmark., Luke A; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Mckenzie CA; Tropical Metabolism Research Unit, Tropical Medicine Research Institute, University of the West Indies, Mona JMAAW15, Jamaica., Palotie A; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Massachusetts General Hospital, Center for Human Genetic Research, Psychiatric and Neurodevelopmental Genetics Unit, Boston, Massachusetts 02114, USA., Pedersen O; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany., Strauch K; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, 85764 Neuherberg, Germany.; Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, 81377 Munich, Germany., Tayo BO; Department of Public Health Sciences, Stritch School of Medicine, Loyola University Chicago, Maywood, Illinois 61053, USA., Wareham NJ; MRC Epidemiology Unit, University of Cambridge School of Clinical Medicine, Institute of Metabolic Science, University of Cambridge, Cambridge Biomedical Campus, Cambridge CB2 0QQ, UK., Bennett DA; Rush Alzheimer's Disease Center, Rush University Medical Center, Chicago, Illinois 60612, USA., Bertram L; School of Public Health, Faculty of Medicine, Imperial College London, London W6 8RP, UK.; Lübeck Interdisciplinary Platform for Genome Analytics, Institutes of Neurogenetics and Integrative and Experimental Genomics, University of Lübeck, 23562 Lübeck, Germany., Blangero J; South Texas Diabetes and Obesity Institute, University of Texas Rio Grande Valley, Brownsville, Texas 78520., Blüher M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Bouchard C; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Campbell H; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Cho NH; Ajou University School of Medicine, Department of Preventive Medicine, Suwon Kyoung-gi 443-721, Korea., Cummings SR; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Czerwinski SA; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Demuth I; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany.; Institute of Medical and Human Genetics, Charité-Universitätsmedizin Berlin, 13353 Berlin, Germany., Eckardt R; The Berlin Aging Study II; Research Group on Geriatrics; Charité-Universitätsmedizin Berlin, 13347 Berlin, Germany., Eriksson JG; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Department of General Practice and Primary Health Care, University of Helsinki, FI-00014 Helsinki, Finland.; Folkhälsan Research Centre, FI-00290 Helsinki, Finland., Ferrucci L; Translational Gerontology Branch, National Institute on Aging, Baltimore, Maryland 21225, USA., Franco OH; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Froguel P; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Gansevoort RT; University of Groningen, University Medical Center Groningen, Department of Medicine, 9700 RB Groningen, The Netherlands., Hansen T; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Faculty of Health Sciences, University of Southern Denmark, 5000 Odense, Denmark., Harris TB; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, Bethesda, Maryland 20892, USA., Hastie N; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Heliövaara M; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Hofman A; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Jordan JM; Thurston Arthritis Research Center, University of North Carolina at Chapel Hill, Chaper Hill, North Carolina 27599-7280, USA., Jula A; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, FI-33521 Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, FI-33014 Tampere, Finland., Kajantie E; National Institute for Health and Welfare, FI-00271 Helsinki, Finland.; Children's Hospital, Helsinki University Hospital and University of Helsinki, FI-00029 Helsinki, Finland.; Department of Obstetrics and Gynecology, MRC Oulu, Oulu University Hospital and University of Oulu, FI-90029 Oulu, Finland., Knekt PB; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Koskinen S; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Kovacs P; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany., Lehtimäki T; Department of Clinical Chemistry, University of Tampere School of Medicine, FI-33014 Tampere, Finland.; Department of Clinical Chemistry, Fimlab Laboratories and School of Medicine, University of Tampere, FI-33520 Tampere, Finland., Lind L; Department of Medical Sciences, Uppsala University, 751 85 Uppsala, Sweden., Liu Y; Center for Human Genetics, Division of Public Health Sciences, Wake Forest School of Medicine, Winston-Salem, North Carolina 27157, USA., Orwoll ES; Bone &Mineral Unit, Oregon Health &Science University, Portland, Oregon 97239, USA., Osmond C; MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton General Hospital, Southampton SO16 6YD, UK., Perola M; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland.; Estonian Genome Center, Univeristy of Tartu, Tartu, 51010, Estonia.; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Pérusse L; Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6.; Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, FI-20521 Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, FI-20520 Turku, Finland., Rankinen T; Human Genomics Laboratory, Pennington Biomedical Research Center, Baton Rouge, Los Angeles 70808, USA., Rao DC; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA., Rice TK; Division of Biostatistics, Washington University School of Medicine, St Louis, Missouri 63110, USA.; Department of Psychiatry, Washington University School of Medicine, St Louis, Missouri 63110, USA., Rivadeneira F; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., Rudan I; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Salomaa V; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Sørensen TI; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited.; Novo Nordisk Foundation Center for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, 2100 Copenhagen, Denmark.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, The Capital Region, 2000 Frederiksberg, Denmark., Stumvoll M; University of Leipzig, IFB Adiposity Diseases, 04103 Leipzig, Germany.; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Tönjes A; University of Leipzig, Department of Medicine, 04103 Leipzig, Germany., Towne B; Lifespan Health Research Center, Wright State University Boonshoft School of Medicine, Dayton, Ohio 45420, USA., Tranah GJ; California Pacific Medical Center Research Institute, San Francisco, California 94107, USA., Tremblay A; Department of Kinesiology, Laval University, Québec City, Quebec, Canada G1V 0A6., Uitterlinden AG; Department of Internal Medicine, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands.; Netherlands Genomics Initiative (NGI)-sponsored Netherlands Consortium for Healthy Aging (NCHA), Rotterdam The Netherlands.; Department of Epidemiology, Erasmus Medical Center, 3015GE Rotterdam, The Netherlands., van der Harst P; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute Netherlands-Netherlands Heart Institute, 3501 DG Utrecht, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Vartiainen E; National Institute for Health and Welfare, FI-00271 Helsinki, Finland., Viikari JS; Department of Medicine, University of Turku, FI-20521 Turku, Finland., Vitart V; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK., Vohl MC; Institute of Nutrition and Functional Foods, Laval University, Québec City, Quebec, Canada G1V 0A6.; School of Nutrition, Laval University, Québec City, Quebec, Canada G1V 0A6., Völzke H; Institute for Community Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany.; DZD (German Centre for Diabetes Research), partner site Greifswald, 17475 Greifswald, Germany., Walker M; Program in Medical and Population Genetics, Broad Institute of Harvard and Massachusetts Institute of Technology, Cambridge, Massachusetts 02142, USA.; Institute of Cellular Medicine, Newcastle University, Newcastle NE2 4HH, UK., Wallaschofski H; Institute of Clinical Chemistry and Laboratory Medicine, University Medicine Greifswald, 17475 Greifswald, Germany.; DZHK (German Centre for Cardiovascular Research), partner site Greifswald, 17475 Greifswald, Germany., Wild S; Centre for Population Health Sciences, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Edinburgh EH8 9AG, UK., Wilson JF; MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, UK.; Centre for Global Health Research, Usher Institute of Population Health Sciences and Informatics, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK., Yengo L; CNRS UMR 8199, F-59019 Lille, France.; European Genomic Institute for Diabetes, 59000 Lille, France.; Université de Lille 2, 59000 Lille, France., Bishop DT; Leeds Institute of Cancer and Pathology, Cancer Research UK Leeds Centre, University of Leeds, Leeds LS9 7TF, UK., Borecki IB; Division of Statistical Genomics, Department of Genetics, Washington University School of Medicine, St Louis, Missouri 63108, USA.; Analytical Genetics Group, Regeneron Genetics Center, Regeneron Pharmaceuticals, Inc., Tarrytown, New York 10591, USA., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London W2 1PG, UK.; Ealing Hospital NHS Trust, Middlesex UB1 3HW, UK.; Imperial College Healthcare NHS Trust, London W12 0HS, UK., Cupples LA; Department of Biostatistics, Boston University School of Public Health, Boston, Massachusetts 02118, USA.; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA., Dehghan A; Department of Epidemiology, Erasmus Medical Center, 3000CA Rotterdam/Zuidholland, The Netherlands., Deloukas P; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London EC1M 6BQ, UK.; Wellcome Trust Sanger Institute, Human Genetics, Hinxton, Cambridge CB10 1SA, UK.; Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 21589, Saudi Arabia., Fatemifar G; MRC Integrative Epidemiology Unit, School of Social and Community Medicine, University of Bristol, Bristol BS82BN, UKnited., Fox C; Harvard Medical School, Boston, Massachusetts 02115, USA.; National Heart, Lung, and Blood Institute, the Framingham Heart Study, Framingham, Massachusetts 01702, USA., Furey TS; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina 27599, USA.; Department of Biology, University of North Carolina, Chapel Hill, North Carolina 27599, USA., Franke L; University of Groningen, University Medical Center Groningen, Department of Cardiology, 9700 RB Groningen, The Netherlands.; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Han J; Department of Epidemiology, Richard M. Fairbanks School of Public Health, Melvin and Bren Simon Cancer Center, Indianapolis, Indiana 46202, USA., Hunter DJ; Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge 2142, USA.; Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts 02115, USA.; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts 02115, USA., Karjalainen J; Department of Genetics, University Medical Center Groningen, University of Groningen, 9700 RB Groningen, The Netherlands., Karpe F; Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK.; Oxford NIHR Biomedical Research Centre, Oxford OX3 7LJ, UK., Kaplan RC; Department of Epidemiology and Popualtion Health, Albert Einstein College of Medicine, Bronx, New York 10461, USA., Kooner JS; 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Department Epidemiology, Biostatistics and Human Genetics, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.; Department of Medicine, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2.; Department of Twin Research, King's College London, London SE1 1E7, UK.; Division of Endocrinology, Lady Davis Institute, Jewish General Hospital, McGill University, Montréal, Quebec, Canada H3T1E2., Schadt EE; Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA.; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York 10029, USA., Spector TD; Department of Twin Research and Genetic Epidemiology, King's College London, London SE1 7EH, UK., Widén E; Institute for Molecular Medicine Finland, University of Helsinki, FI-00290 Helsinki, Finland., Willer CJ; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan 48109, USA.; 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Publikováno v:
Nature communications [Nat Commun] 2016 Feb 01; Vol. 7, pp. 10495. Date of Electronic Publication: 2016 Feb 01.