Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jina Yu"'
Autor:
Jina Yu, Chunli Yan, Thomas Dodd, Chi-Lin Tsai, John A. Tainer, Susan E. Tsutakawa, Ivaylo Ivanov
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Transcription factor IIH (TFIIH) is a protein assembly essential for transcription initiation and nucleotide excision repair (NER). Yet, understanding of the conformational switching underpinning these diverse TFIIH functions remains fragmen
Externí odkaz:
https://doaj.org/article/ae5a3d72e0f443e8bd13f58a35d7e016
Autor:
Chunli Yan, Thomas Dodd, Jina Yu, Bernice Leung, Jun Xu, Juntaek Oh, Dong Wang, Ivaylo Ivanov
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Here the authors provide models of RNA polymerase II bound to the yeast CSB ortholog Rad26 in different nucleotide states; explain how Rad26 domain motions help the polymerase progress past DNA lesions; and interpret the effects of CSB-associated dis
Externí odkaz:
https://doaj.org/article/5e33c934a5cc481e9029a08bb4340ef4
Autor:
Bernice Leung, Thomas Dodd, Chunli Yan, Jun Xu, Ivaylo Ivanov, Dong Wang, Juntaek Oh, Jina Yu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Nature Communications
Nature Communications
Transcription-coupled repair is essential for the removal of DNA lesions from the transcribed genome. The pathway is initiated by CSB protein binding to stalled RNA polymerase II. Mutations impairing CSB function cause severe genetic disease. Yet, th
Autor:
Jina Yun, Simon Hansen, Otto Morris, David T. Madden, Clare Peters Libeu, Arjun J. Kumar, Cameron Wehrfritz, Aaron H. Nile, Yingnan Zhang, Lijuan Zhou, Yuxin Liang, Zora Modrusan, Michelle B. Chen, Christopher C. Overall, David Garfield, Judith Campisi, Birgit Schilling, Rami N. Hannoush, Heinrich Jasper
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Cellular senescence and associated secretory phenotype (SASP) are thought to contribute to aging and tissue dysfunction, though it is unclear how SASP impacts regeneration. Here the authors show that SASP factors impair regeneration, and that Ptk7 is
Externí odkaz:
https://doaj.org/article/0efe9bd563954738a88ecc378c67fcb4
Autor:
Huan Yang, Caroline Sibilla, Raymond Liu, Jina Yun, Bruce A. Hay, Craig Blackstone, David C. Chan, Robert J. Harvey, Ming Guo
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Drp1 is the master regulator of mitochondrial fission, which has important impact on cellular functions. Here, Yang et al identified evolutionarily conserved proteins Clueless and its homolog CLUH as key regulators of Drp1 that function via translati
Externí odkaz:
https://doaj.org/article/295bcd55fca249279a87c90de815fa7a
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Stem cell migration is critical during adult tissue regeneration. Here, the authors demonstrate that enteroendocrine cells coordinate stem cell migration towards sites of injury in the Drosophila intestine by activating non-canonical Wnt signaling.
Externí odkaz:
https://doaj.org/article/c22dd75450614573a27bc0d118fd971a