Zobrazeno 1 - 7
of 7
pro vyhledávání: '"James A. Brown"'
Autor:
Benoit Pugin, Weronika Barcik, Peter Schmid-Grendelmeier, David L. Mayhew, Liam O'Mahony, Marek Jutel, Noelia Rodriguez-Perez, Stephanie Van Horn, Pawel Gajdanowicz, Remo Frei, Katrine Graversen, Noriane A. Sievi, Milena Sokolowska, Sylwia Smolinska, Edith M. Hessel, Ken A. Saunders, Can Altunbulakli, Magdalena Kurnik-Lucka, Michal Pirozynski, David Michalovich, Sorif Uddin, Cezmi A. Akdis, Andrzej Eljaszewicz, Katrine Lindholm Bøgh, Karen D. Simpson, James R. Brown, Malcolm Kohler, Ruth Ferstl
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Michalovich, D, Rodriguez-Perez, N, Smolinska, S, Pirozynski, M, Mayhew, D, Uddin, S, Van Horn, S, Sokolowska, M, Altunbulakli, C, Eljaszewicz, A, Pugin, B, Barcik, W, Kurnik-Lucka, M, Saunders, K A, Simpson, K D, Schmid-Grendelmeier, P, Ferstl, R, Frei, R, Sievi, N, Kohler, M, Gajdanowicz, P, Graversen, K B, Bøgh, K L, Jutel, M, Brown, J R, Akdis, C A, Hessel, E M & O'Mahony, L 2019, ' Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients ', Nature Communications, vol. 10, 5711 . https://doi.org/10.1038/s41467-019-13751-9
Nature Communications
Michalovich, D, Rodriguez-Perez, N, Smolinska, S, Pirozynski, M, Mayhew, D, Uddin, S, Van Horn, S, Sokolowska, M, Altunbulakli, C, Eljaszewicz, A, Pugin, B, Barcik, W, Kurnik-Lucka, M, Saunders, K A, Simpson, K D, Schmid-Grendelmeier, P, Ferstl, R, Frei, R, Sievi, N, Kohler, M, Gajdanowicz, P, Graversen, K B, Bøgh, K L, Jutel, M, Brown, J R, Akdis, C A, Hessel, E M & O'Mahony, L 2019, ' Obesity and disease severity magnify disturbed microbiome-immune interactions in asthma patients ', Nature Communications, vol. 10, 5711 . https://doi.org/10.1038/s41467-019-13751-9
In order to improve targeted therapeutic approaches for asthma patients, insights into the molecular mechanisms that differentially contribute to disease phenotypes, such as obese asthmatics or severe asthmatics, are required. Here we report immunolo
Publikováno v:
Nature Communications
Nature communications, vol 7, iss 1
Zhang, W; Mao, JH; Zhu, W; Jain, AK; Liu, K; Brown, JB; et al.(2016). Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy. Nature Communications, 7. doi: 10.1038/ncomms12619. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/12t1v6pn
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Nature communications, vol 7, iss 1
Zhang, W; Mao, JH; Zhu, W; Jain, AK; Liu, K; Brown, JB; et al.(2016). Centromere and kinetochore gene misexpression predicts cancer patient survival and response to radiotherapy and chemotherapy. Nature Communications, 7. doi: 10.1038/ncomms12619. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/12t1v6pn
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Chromosomal instability (CIN) is a hallmark of cancer that contributes to tumour heterogeneity and other malignant properties. Aberrant centromere and kinetochore function causes CIN through chromosome missegregation, leading to aneuploidy, rearrange
Autor:
Maaike C. Swets, Steven Kerr, James Scott-Brown, Adam B. Brown, Rishi Gupta, Jonathan E. Millar, Enti Spata, Fiona McCurrach, Andrew D. Bretherick, Annemarie Docherty, David Harrison, Kathy Rowan, Neil Young, ISARIC4C Investigators, Geert H. Groeneveld, Jake Dunning, Jonathan S. Nguyen-Van-Tam, Peter Openshaw, Peter W. Horby, Ewen Harrison, Natalie Staplin, Malcolm G. Semple, Nazir Lone, J. Kenneth Baillie
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Choosing optimal outcome measures maximizes statistical power, accelerates discovery and improves reliability in early-phase trials. We devised and evaluated a modification to a pragmatic measure of oxygenation function, the $$S/F$$ S / F ra
Externí odkaz:
https://doaj.org/article/009fd47cdad84e04b276c3c4dbe7d8d5
Autor:
David Michalovich, Noelia Rodriguez-Perez, Sylwia Smolinska, Michal Pirozynski, David Mayhew, Sorif Uddin, Stephanie Van Horn, Milena Sokolowska, Can Altunbulakli, Andrzej Eljaszewicz, Benoit Pugin, Weronika Barcik, Magdalena Kurnik-Lucka, Ken A. Saunders, Karen D. Simpson, Peter Schmid-Grendelmeier, Ruth Ferstl, Remo Frei, Noriane Sievi, Malcolm Kohler, Pawel Gajdanowicz, Katrine B. Graversen, Katrine Lindholm Bøgh, Marek Jutel, James R. Brown, Cezmi A. Akdis, Edith M. Hessel, Liam O’Mahony
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Here, the authors characterize immunological and microbiome alterations in a cohort of obese asthmatics, finding that disease severity negatively correlates with fecal abundance of Akkermansia muciniphila, and show in a mouse model that administratio
Externí odkaz:
https://doaj.org/article/cd01b505faaf4615b453f12d29b2725d
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-15 (2016)
Centromeres and kinetochores are important in maintaining chromosomal stability. Here, the authors show that overexpression of a subset of centromere and kinetochore genes is associated with chromosomal instability and mutation burden in cancer, and
Externí odkaz:
https://doaj.org/article/81d5d64089a14736a7f1215807ef737a
Autor:
Jizhong Zhou, Ye Deng, Lina Shen, Chongqing Wen, Qingyun Yan, Daliang Ning, Yujia Qin, Kai Xue, Liyou Wu, Zhili He, James W. Voordeckers, Joy D. Van Nostrand, Vanessa Buzzard, Sean T. Michaletz, Brian J. Enquist, Michael D. Weiser, Michael Kaspari, Robert Waide, Yunfeng Yang, James H. Brown
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Climate warming has a wide range of effects on biodiversity. Here, Zhou et al. show that although variation in environmental temperature is a primary driver of soil microbial biodiversity, microbes show much lower rates of turnover across temperature
Externí odkaz:
https://doaj.org/article/526dd99a1c5a49a5bb3c3925df9cca3e
Autor:
Jizhong Zhou, Ye Deng, Lina Shen, Chongqing Wen, Qingyun Yan, Daliang Ning, Yujia Qin, Kai Xue, Liyou Wu, Zhili He, James W. Voordeckers, Joy D. Van Nostrand, Vanessa Buzzard, Sean T. Michaletz, Brian J. Enquist, Michael D. Weiser, Michael Kaspari, Robert Waide, Yunfeng Yang, James H. Brown
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-2 (2017)
Externí odkaz:
https://doaj.org/article/659dee7b899c45f5a1be6f1bd8232553