Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Drexler, P."'
Autor:
Mia Kvåle Løvmo, Shiyu Deng, Simon Moser, Rainer Leitgeb, Wolfgang Drexler, Monika Ritsch-Marte
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Organoid and spheroid technology provide valuable insights into developmental biology and oncology. Optical coherence tomography (OCT) is a label-free technique that has emerged as an excellent tool for monitoring the structure and function
Externí odkaz:
https://doaj.org/article/64895629451342cfa5479802eb0e1ffa
Autor:
Tirtha Chanda, Katja Hauser, Sarah Hobelsberger, Tabea-Clara Bucher, Carina Nogueira Garcia, Christoph Wies, Harald Kittler, Philipp Tschandl, Cristian Navarrete-Dechent, Sebastian Podlipnik, Emmanouil Chousakos, Iva Crnaric, Jovana Majstorovic, Linda Alhajwan, Tanya Foreman, Sandra Peternel, Sergei Sarap, İrem Özdemir, Raymond L. Barnhill, Mar Llamas-Velasco, Gabriela Poch, Sören Korsing, Wiebke Sondermann, Frank Friedrich Gellrich, Markus V. Heppt, Michael Erdmann, Sebastian Haferkamp, Konstantin Drexler, Matthias Goebeler, Bastian Schilling, Jochen S. Utikal, Kamran Ghoreschi, Stefan Fröhling, Eva Krieghoff-Henning, Reader Study Consortium, Titus J. Brinker
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Artificial intelligence (AI) systems have been shown to help dermatologists diagnose melanoma more accurately, however they lack transparency, hindering user acceptance. Explainable AI (XAI) methods can help to increase transparency, yet oft
Externí odkaz:
https://doaj.org/article/a7c398cf0b3b4b35ad5fc17b7f22b907
Autor:
Franziska Günl, Tim Krischuns, Julian A. Schreiber, Lea Henschel, Marius Wahrenburg, Hannes C. A. Drexler, Sebastian A. Leidel, Vlad Cojocaru, Guiscard Seebohm, Alexander Mellmann, Martin Schwemmle, Stephan Ludwig, Linda Brunotte
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Influenza A virus replication relies on host cell-derived ubiquitination of the viral polymerase. Here, Günl et al. show that site-specific ubiquitination of PB1-K578 is acquired during infection and facilitates spatiotemporal control of polymerase
Externí odkaz:
https://doaj.org/article/d155a95c62414014bbf6fda9c189f4be
Autor:
Matteo Rizzato, Fuxiang Mao, Florian Chardon, Kun-Yi Lai, Ruth Villalonga-Planells, Hannes C. A. Drexler, Marion E. Pesenti, Mert Fiskin, Nora Roos, Kelly M. King, Shuaizhi Li, Eduardo R. Gamez, Lilo Greune, Petra Dersch, Claudia Simon, Murielle Masson, Koenraad Van Doorslaer, Samuel K. Campos, Mario Schelhaas
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Human papillomavirus (HPV) coopts mitosis for nuclear entry by tethering the viral DNA to mitotic chromosomes, a process facilitated by the viral minor capsid protein L2. Here, Rizzato et al. show that L2 contains conserved phosphorylation motifs wit
Externí odkaz:
https://doaj.org/article/b57b1e1f90134a7ead1de9a3cb32c825
Akademický článek
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Autor:
Binyamin Duethorn, Fabian Groll, Bettina Rieger, Hannes C. A. Drexler, Heike Brinkmann, Ludmila Kremer, Martin Stehling, Marie-Theres Borowski, Karina Mildner, Dagmar Zeuschner, Magdalena Zernicka-Goetz, Marc P. Stemmler, Karin B. Busch, Juan M. Vaquerizas, Ivan Bedzhov
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
How pluripotency transcription factors regulate the cellular architecture and energetics has remained largely unknown. Here the authors identify Lima1 as a key effector that mediates the pluripotency control of membrane dynamics and cellular metaboli
Externí odkaz:
https://doaj.org/article/ec59b98c93f041c9b516251c4f4d904c
Autor:
Eva Bertosin, Christopher M. Maffeo, Thomas Drexler, Maximilian N. Honemann, Aleksei Aksimentiev, Hendrik Dietz
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-11 (2021)
Biological molecular motors convert chemical energy into mechanical motion by coupling catalytic reactions to large-scale structural transitions. Here, the authors report the design of a rotating DNA nanomechanism that comprises a camshaft whose rota
Externí odkaz:
https://doaj.org/article/256256d877644e40ba9afe046f37c84b
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
James A. Hutchinson, Katharina Kronenberg, Paloma Riquelme, Jürgen J. Wenzel, Gunther Glehr, Hannah-Lou Schilling, Florian Zeman, Katja Evert, Martin Schmiedel, Marion Mickler, Konstantin Drexler, Florian Bitterer, Laura Cordero, Lukas Beyer, Christian Bach, Josef Koestler, Ralph Burkhardt, Hans J. Schlitt, Dirk Hellwig, Jens M. Werner, Rainer Spang, Barbara Schmidt, Edward K. Geissler, Sebastian Haferkamp
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Checkpoint blocking therapies are used to treat metastatic melanoma, but can have adverse immune-mediated effects, including liver pathology. Here the authors identify an expanded pool of CD4+ effector memory T cells resulting from prior CMV exposure
Externí odkaz:
https://doaj.org/article/f92b658607e1458c8aa40adb3861c519
Autor:
Halime Kalkavan, Piyush Sharma, Stefan Kasper, Iris Helfrich, Aleksandra A. Pandyra, Asmae Gassa, Isabel Virchow, Lukas Flatz, Tim Brandenburg, Sukumar Namineni, Mathias Heikenwalder, Bastian Höchst, Percy A. Knolle, Guido Wollmann, Dorothee von Laer, Ingo Drexler, Jessica Rathbun, Paula M. Cannon, Stefanie Scheu, Jens Bauer, Jagat Chauhan, Dieter Häussinger, Gerald Willimsky, Max Löhning, Dirk Schadendorf, Sven Brandau, Martin Schuler, Philipp A. Lang, Karl S. Lang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Viruses are promising anti-tumour therapeutics due to induction of an immune response and/or oncolytic activity. Here, Kalkavanet al. show that LCMV replicates in tumour cells, without inducing cell lysis, and that its anti-tumour activity is largely
Externí odkaz:
https://doaj.org/article/2452e9d8f1cb48cd9071ab5ededf8f25