Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Brian, Davidson"'
Autor:
Calum Forrest, Thomas J. G. Chase, Antonia O. Cuff, Dionas Maroulis, Reza Motallebzadeh, Amir Gander, Brian Davidson, Paul Griffiths, Victoria Male, Matthew Reeves
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Natural killer cells play important roles in the immune response to human cytomegalovirus infection. Here the authors implicate donor-derived liver resident natural killer cells in the control of human cytomegalovirus infection by analysis of perfusa
Externí odkaz:
https://doaj.org/article/e8f8750db14146caa9acd9f57f869526
Targeting human Acyl-CoA:cholesterol acyltransferase as a dual viral and T cell metabolic checkpoint
Autor:
Nathalie M. Schmidt, Peter A. C. Wing, Mariana O. Diniz, Laura J. Pallett, Leo Swadling, James M. Harris, Alice R. Burton, Anna Jeffery-Smith, Nekisa Zakeri, Oliver E. Amin, Stephanie Kucykowicz, Mirjam H. Heemskerk, Brian Davidson, Tim Meyer, Joe Grove, Hans J. Stauss, Ines Pineda-Torra, Clare Jolly, Elizabeth C. Jury, Jane A. McKeating, Mala K. Maini
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Shared metabolic pathways could allow simultaneous manipulation of T cells, viruses and tumours. Here the authors show targeting cholesterol esterification restrains hepatitis B in vitro, whilst bolstering exhausted antigen-specific T cell responses
Externí odkaz:
https://doaj.org/article/80c091a62a0e452aadda8e67b452162c