Zobrazeno 1 - 10
of 382
pro vyhledávání: '"35"'
Autor:
Fang X; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Zeng Y; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Huang Y; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Zhu Z; State Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, 94 Weijin Road, Tianjin, 300071, PR China., Lin S; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Xu W; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Zheng C; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China., Hu X; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China. xinweihu@gzhmu.edu.cn., Qiu Y; State Key Laboratory and Institute of Elemento-Organic Chemistry, Frontiers Science Center for New Organic Matter, College of Chemistry, Nankai University, 94 Weijin Road, Tianjin, 300071, PR China. qiuyouai@nankai.edu.cn., Ruan Z; Guangzhou Municipal and Guangdong Provincial Key Laboratory of Molecular Target & Clinical Pharmacology and the State Key Laboratory of Respiratory Disease, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Guangzhou Medical University, Guangzhou, 511436, PR China. zruan@gzhmu.edu.cn.
Publikováno v:
Nature communications [Nat Commun] 2024 Jun 18; Vol. 15 (1), pp. 5181. Date of Electronic Publication: 2024 Jun 18.
Autor:
Jefferson RE; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Oggier A; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Füglistaler A; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Camviel N; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland.; Department of Oncology UNIL-CHUV, University Hospital Lausanne (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland., Hijazi M; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Villarreal AR; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland., Arber C; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland.; Department of Oncology UNIL-CHUV, University Hospital Lausanne (CHUV), University of Lausanne (UNIL), Lausanne, Switzerland., Barth P; Interfaculty Institute of Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, CH-1015, Switzerland. patrick.barth@epfl.ch.; Ludwig Institute for Cancer Research Lausanne, Lausanne, Switzerland. patrick.barth@epfl.ch.
Publikováno v:
Nature communications [Nat Commun] 2023 May 19; Vol. 14 (1), pp. 2875. Date of Electronic Publication: 2023 May 19.
Autor:
Gomez-Zepeda D; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany. david.gomez-zepeda@dkfz-heidelberg.de.; Helmholtz Institute for Translational Oncology Mainz (HI-TRON Mainz) - A Helmholtz Institute of the DKFZ, Mainz, Germany. david.gomez-zepeda@dkfz-heidelberg.de.; German Cancer Research Center (DKFZ) Heidelberg, Division 191, Heidelberg, Germany. david.gomez-zepeda@dkfz-heidelberg.de., Arnold-Schild D; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Beyrle J; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.; Helmholtz Institute for Translational Oncology Mainz (HI-TRON Mainz) - A Helmholtz Institute of the DKFZ, Mainz, Germany.; German Cancer Research Center (DKFZ) Heidelberg, Division 191, Heidelberg, Germany., Declercq A; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Gabriels R; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Kumm E; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Preikschat A; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Łącki MK; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Hirschler A; BioOrganic Mass Spectrometry Laboratory (LSMBO), IPHC UMR 7178, University of Strasbourg, CNRS, ProFI - FR2048, Strasbourg, France., Rijal JB; BioOrganic Mass Spectrometry Laboratory (LSMBO), IPHC UMR 7178, University of Strasbourg, CNRS, ProFI - FR2048, Strasbourg, France., Carapito C; BioOrganic Mass Spectrometry Laboratory (LSMBO), IPHC UMR 7178, University of Strasbourg, CNRS, ProFI - FR2048, Strasbourg, France., Martens L; VIB-UGent Center for Medical Biotechnology, VIB, Ghent, Belgium.; Department of Biomolecular Medicine, Ghent University, Ghent, Belgium., Distler U; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Schild H; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes-Gutenberg University, Mainz, Germany., Tenzer S; Institute of Immunology, University Medical Center of the Johannes-Gutenberg University, Mainz, Germany. tenzer@uni-mainz.de.; Helmholtz Institute for Translational Oncology Mainz (HI-TRON Mainz) - A Helmholtz Institute of the DKFZ, Mainz, Germany. tenzer@uni-mainz.de.; German Cancer Research Center (DKFZ) Heidelberg, Division 191, Heidelberg, Germany. tenzer@uni-mainz.de.; Research Center for Immunotherapy (FZI), University Medical Center of the Johannes-Gutenberg University, Mainz, Germany. tenzer@uni-mainz.de.
Publikováno v:
Nature communications [Nat Commun] 2024 Mar 13; Vol. 15 (1), pp. 2288. Date of Electronic Publication: 2024 Mar 13.
Autor:
Callahan AJ; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Gandhesiri S; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Travaline TL; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA., Reja RM; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Lozano Salazar L; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Hanna S; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Lee YC; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA.; Department of Chemistry, National Cheng Kung University, No.1, University Road, Tainan City, 701, Taiwan., Li K; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA., Tokareva OS; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA., Swiecicki JM; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA.; Relay Therapeutics, Inc., 399 Binney Street, 2nd Floor, Cambridge, MA, 02139, USA., Loas A; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA., Verdine GL; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA.; Department of Stem Cell and Regenerative Biology, Harvard University, 7 Divinity Avenue, Cambridge, MA, 02138, USA.; Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA, 02138, USA.; Department of Molecular and Cellular Biology, Harvard University, 52 Oxford Street, Cambridge, MA, 02138, USA., McGee JH; FOG Pharmaceuticals Inc., 30 Acorn Park Drive, Cambridge, MA, 02140, USA. jmcgee@fogpharma.com., Pentelute BL; Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. blp@mit.edu.; The Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, 500 Main Street, Cambridge, MA, 02142, USA. blp@mit.edu.; Center for Environmental Health Sciences, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA, 02139, USA. blp@mit.edu.; Broad Institute of MIT and Harvard, 415 Main Street, Cambridge, MA, 02142, USA. blp@mit.edu.
Publikováno v:
Nature communications [Nat Commun] 2024 Feb 28; Vol. 15 (1), pp. 1813. Date of Electronic Publication: 2024 Feb 28.
Autor:
Matzinger M; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria. manuel.matzinger@imp.ac.at., Schmücker A; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.; MRC (Medical Research Council) London Institute of Medical Sciences, Du Cane Road, London, W12 0NN, UK.; Institute of Clinical Sciences, Imperial College London, Hammersmith Hospital Campus, Du Cane Road, London, W12 0NN, UK., Yelagandula R; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.; Laboratory of Epigenetics, Cell Fate & Disease, Centre for DNA Fingerprinting and Diagnostics (CDFD), Uppal, Hyderabad, India., Stejskal K; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria.; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria., Krššáková G; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria.; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria., Berger F; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria., Mechtler K; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria. karl.mechtler@imp.ac.at.; Gregor Mendel Institute of Molecular Plant Biology (GMI), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria. karl.mechtler@imp.ac.at.; Institute of Molecular Biotechnology (IMBA), Austrian Academy of Sciences, Vienna BioCenter (VBC), Vienna, Austria. karl.mechtler@imp.ac.at., Mayer RL; Research Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria. rupert.mayer@imp.ac.at.
Publikováno v:
Nature communications [Nat Commun] 2024 Feb 03; Vol. 15 (1), pp. 1019. Date of Electronic Publication: 2024 Feb 03.
Design-rules for stapled peptides with in vivo activity and their application to Mdm2/X antagonists.
Autor:
Chandramohan A; MSD International, Singapore, 138665, Singapore., Josien H; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Yuen TY; Institute of Sustainability for Chemicals, Energy and Environment, Agency for Science, Technology and Research (ASTAR), Singapore, 138665, Singapore., Duggal R; Merck & Co., Inc., Boston, MA, 02115, USA., Spiegelberg D; Department of Surgical Sciences, Uppsala University, Uppsala, Sweden., Yan L; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Juang YA; MSD International, Singapore, 138665, Singapore., Ge L; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Aronica PG; Bioinformatics Institute, Agency for Science, Technology and Research (ASTAR), Singapore, 138671, Singapore., Kaan HYK; MSD International, Singapore, 138665, Singapore., Lim YH; Institute of Sustainability for Chemicals, Energy and Environment, Agency for Science, Technology and Research (ASTAR), Singapore, 138665, Singapore., Peier A; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Sherborne B; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Hochman J; Merck & Co., Inc., West Point, PA, 19486, USA., Lin S; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Biswas K; Merck & Co., Inc., Boston, MA, 02115, USA., Nestor M; Department of Immunology, Genetics and Pathology, Uppsala University, Uppsala, Sweden., Verma CS; Bioinformatics Institute, Agency for Science, Technology and Research (ASTAR), Singapore, 138671, Singapore., Lane DP; Institute of Molecular and Cell Biology, Singapore, 138673, Singapore., Sawyer TK; Merck & Co., Inc., Boston, MA, 02115, USA., Garbaccio R; Merck & Co., Inc., Kenilworth, NJ, 07033, USA., Henry B; MSD International, Singapore, 138665, Singapore. brian.henry3@msd.com., Kannan S; Bioinformatics Institute, Agency for Science, Technology and Research (ASTAR), Singapore, 138671, Singapore. raghavk@bii.a-star.edu.sg., Brown CJ; Institute of Molecular and Cell Biology, Singapore, 138673, Singapore. CJBrown@imcb.a-star.edu.sg., Johannes CW; Institute of Sustainability for Chemicals, Energy and Environment, Agency for Science, Technology and Research (ASTAR), Singapore, 138665, Singapore. cwjohannes@gmail.com.; Institute of Molecular and Cell Biology, Singapore, 138673, Singapore. cwjohannes@gmail.com.; EPOC Scientific LLC, Stoneham, MA, 02180, USA. cwjohannes@gmail.com., Partridge AW; MSD International, Singapore, 138665, Singapore. partridge.anthony@gene.com.; Genentech, South San Francisco, CA, 94080, USA. partridge.anthony@gene.com.
Publikováno v:
Nature communications [Nat Commun] 2024 Jan 12; Vol. 15 (1), pp. 489. Date of Electronic Publication: 2024 Jan 12.
Autor:
Pei ZF; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Zhu L; School of Chemical Sciences, NMR Laboratory, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA., Nair SK; Department of Biochemistry, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. snair@illinois.edu.; Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. snair@illinois.edu.; Center for Biophysics and Quantitative Biology, University of Illinois at Urbana-Champaign, Urbana, IL, 61801, USA. snair@illinois.edu.
Publikováno v:
Nature communications [Nat Commun] 2023 Nov 25; Vol. 14 (1), pp. 7734. Date of Electronic Publication: 2023 Nov 25.
Autor:
Oeller M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK.; Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Kang RJD; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK., Bolt HL; Hit Discovery, Discovery Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK., Gomes Dos Santos AL; Advanced Drug Delivery, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Cambridge, United Kingdom., Weinmann AL; Early Chemical Development, Pharmaceutical Sciences, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Nikitidis A; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Zlatoidsky P; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Su W; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Czechtizky W; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., De Maria L; Medicinal Chemistry, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Gothenburg, Sweden., Sormanni P; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK. ps589@cam.ac.uk., Vendruscolo M; Centre for Misfolding Diseases, Yusuf Hamied Department of Chemistry, University of Cambridge, Cambridge, UK. mv245@cam.ac.uk.
Publikováno v:
Nature communications [Nat Commun] 2023 Nov 17; Vol. 14 (1), pp. 7475. Date of Electronic Publication: 2023 Nov 17.
Autor:
Booth R; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705, Santiago de Compostela, Spain., Insua I; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705, Santiago de Compostela, Spain., Ahmed S; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705, Santiago de Compostela, Spain., Rioboo A; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705, Santiago de Compostela, Spain., Montenegro J; Centro Singular de Investigación en Química Biolóxica e Materiais Moleculares (CiQUS), Departamento de Química Orgánica, Universidade de Santiago de Compostela, 15705, Santiago de Compostela, Spain. javier.montenegro@usc.es.
Publikováno v:
Nature communications [Nat Commun] 2021 Nov 05; Vol. 12 (1), pp. 6421. Date of Electronic Publication: 2021 Nov 05.
Autor:
Tian ZY; Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, People's Republic of China., Zhang Z; Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, People's Republic of China., Wang S; Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, People's Republic of China., Lu H; Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing, 100871, People's Republic of China. chemhualu@pku.edu.cn.
Publikováno v:
Nature communications [Nat Commun] 2021 Oct 04; Vol. 12 (1), pp. 5810. Date of Electronic Publication: 2021 Oct 04.