Zobrazeno 1 - 2
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pro vyhledávání: '"Ye Zheng"'
Autor:
Johan Auwerx, Ying Cui, Ruth T. Yu, Ronald M. Evans, Jianrong Wang, Hui Xiao, Caroline Zhang, Shuo Zhang, Annette R. Atkins, Ye Zheng, Na Zhang, Ruihong Zhu, Nanhai He, Michael Downes, Dexian Quan, Christopher Liddle, Qibin Leng, Chunhui Yang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Thymocytes must pass both positive and negative selections to become mature T cells. Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity to self-peptide MHC complexes (self pMHC) to avoid autoimmune diseases, while
Autor:
Christina Chang, Jeniffer B. Hernandez, John Le Lay, Klaus H. Kaestner, Marc Montminy, Mathias Leblanc, Ye Zheng, David Grimm
Publikováno v:
Nature communications
Following their activation in response to inflammatory signals, innate immune cells secrete T cell polarizing cytokines that promote the differentiation of naïve CD4 T cells into T helper (Th) cell subsets. Amongst these, Th17 cells play a prominent