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pro vyhledávání: '"Yue Shen"'
Autor:
Zengyi Ma, Cheng Peng, Yongfei Wang, Liangfu Zhou, Yao Zhao, Hongying Ye, Hong Chen, Zhijian Song, Chaowei Fu, Jianhua Chen, Yiming Li, Hong Peng, Cheng Luo, Feng Tang, Dan Zhao, Jiawei Shen, Shiqi Li, Aamir Fahira, Ying Mao, Zhiqiang Li, Wang Ye, Ming Shen, Chuanxin Huang, Xuefei Shou, Daming Gao, Siyu Deng, Zhifeng Shi, Min Chen, Chunjui Chen, Juan Zhou, Yongyong Shi, Qilin Zhang, Zhao Ye, Hai Yan, Yichao Zhang, Xuemin Jian, Lu Xie, Zhenwei Yao, Yue Shen, Zhaoyun Zhang
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
Nature Communications
Nature Communications
Cushing’s disease results from corticotroph adenomas of the pituitary that hypersecrete adrenocorticotropin (ACTH), leading to excess glucocorticoid and hypercortisolism. Mutations of the deubiquitinase gene USP8 occur in 35–62% of corticotroph a