Zobrazeno 1 - 10
of 15
pro vyhledávání: ''
Autor:
Steve Eyre, Magnus Rattray, Peyman Zarrineh, Antony Adamson, Paul Martin, Jing Yang, Peter Fraser, Xiangyu Ge, Andrew P. Morris, Kate Duffus, Amanda McGovern
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Yang, J, Mcgovern, A, Martin, P, Duffus, K, Ge, X, Zarrineh, P, Morris, A, Adamson, A, Fraser, P, Rattray, M & Eyre, S 2020, ' Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis ', Nature Communications, vol. 11, 4402 . https://doi.org/10.1038/s41467-020-18180-7
Nature Communications
Yang, J, Mcgovern, A, Martin, P, Duffus, K, Ge, X, Zarrineh, P, Morris, A, Adamson, A, Fraser, P, Rattray, M & Eyre, S 2020, ' Analysis of chromatin organization and gene expression in T cells identifies functional genes for rheumatoid arthritis ', Nature Communications, vol. 11, 4402 . https://doi.org/10.1038/s41467-020-18180-7
Nature Communications
Genome-wide association studies have identified genetic variation contributing to complex disease risk. However, assigning causal genes and mechanisms has been more challenging because disease-associated variants are often found in distal regulatory
Autor:
Michael Christie, Christina Piermaria, Nicolas Butel, Philippe Hammann, Patricia L. M. Lang, Johana Chicher, Carlos Gomez-Diaz, Detlef Weigel, Ezgi Süheyla Karaaslan, Hervé Vaucheret, David Pflieger, Lauriane Kuhn, Dominique Gagliardi, Heike Lange, Simon Y. A. Ndecky, Julie Zumsteg
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
Nature Communications, Nature Publishing Group, 2019, ⟨10.1038/s41467-019-11807-4⟩
Nature Communications (10), 1-12. (2019)
Nature Communications, Nature Publishing Group, 2019, 10, pp.1-12. ⟨10.1038/s41467-019-11807-4⟩
Nature Communications, 2019, 10, pp.1-12. ⟨10.1038/s41467-019-11807-4⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2019, ⟨10.1038/s41467-019-11807-4⟩
Nature Communications (10), 1-12. (2019)
Nature Communications, Nature Publishing Group, 2019, 10, pp.1-12. ⟨10.1038/s41467-019-11807-4⟩
Nature Communications, 2019, 10, pp.1-12. ⟨10.1038/s41467-019-11807-4⟩
The RNA exosome is a key 3’−5’ exoribonuclease with an evolutionarily conserved structure and function. Its cytosolic functions require the co-factors SKI7 and the Ski complex. Here we demonstrate by co-purification experiments that the ARM-rep
Autor:
Min Huang, Eric A. Bushong, Sebastien Phan, Daniel Boemer, Anton Maximov, Yong-Chuan Zhu, Mark H. Ellisman, Kristin Tsui, Elizabeth Beutter, Marco Uytiepo
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
Nature Communications
The formation of new memories requires transcription. However, the mechanisms that limit signaling of relevant gene programs in space and time for precision of information coding remain poorly understood. We found that, during learning, the cellular
Autor:
Elior Rahmani, Lisa F. Barcellos, Saharon Rosset, Regev Schweiger, Brooke Rhead, Sriram Sankararaman, Eleazar Eskin, Eran Halperin, Lindsey A. Criswell
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature communications, vol 10, iss 1
Nature Communications
Nature communications, vol 10, iss 1
Nature Communications
High costs and technical limitations of cell sorting and single-cell techniques currently restrict the collection of large-scale, cell-type-specific DNA methylation data. This, in turn, impedes our ability to tackle key biological questions that pert
Autor:
Justin Cotney, Thomas A. Stewart, Thomas J. Sanger, Günter P. Wagner, Cong Liang, James P. Noonan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Nature Communications
Nature Communications
In crown group tetrapods, individual digits are homologized in relation to a pentadactyl ground plan. However, testing hypotheses of digit homology is challenging because it is unclear whether digits represent distinct and conserved gene regulatory s
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
Nature Communications
Nature Communications
Genome-wide association studies (GWAS) have identified over 41 susceptibility loci associated with Parkinson’s Disease (PD) but identifying putative causal genes and the underlying mechanisms remains challenging. Here, we leverage large-scale trans
Autor:
Mart Krupovic, Matthew B. Sullivan, Charlotte Guyomar, Carolina Megumi Mizuno, Francisco Rodriguez-Valera, Reynald Gillet, Régis Lavigne, Patrick Forterre, Simon Roux
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Mizuno, CM; Guyomar, C; Roux, S; Lavigne, R; Rodriguez-Valera, F; Sullivan, M; et al.(2017). Numerous cultivated and uncultivated viruses encode ribosomal proteins. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/3mr361nf
Nature Communications, 2019, 10 (1), pp.752. ⟨10.1038/s41467-019-08672-6⟩
Nature communications, vol 10, iss 1
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.752. ⟨10.1038/s41467-019-08672-6⟩
Mizuno, Carolina M; Guyomar, Charlotte; Roux, Simon; Lavigne, Régis; Rodriguez-Valera, Francisco; Sullivan, Matthew B; et al.(2019). Numerous cultivated and uncultivated viruses encode ribosomal proteins.. Nature communications, 10(1), 752. doi: 10.1038/s41467-019-08672-6. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/8f0519r0
Nature Communications
Mizuno, CM; Guyomar, C; Roux, S; Lavigne, R; Rodriguez-Valera, F; Sullivan, M; et al.(2017). Numerous cultivated and uncultivated viruses encode ribosomal proteins. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/3mr361nf
Nature Communications, 2019, 10 (1), pp.752. ⟨10.1038/s41467-019-08672-6⟩
Nature communications, vol 10, iss 1
Nature Communications, Nature Publishing Group, 2019, 10 (1), pp.752. ⟨10.1038/s41467-019-08672-6⟩
Mizuno, Carolina M; Guyomar, Charlotte; Roux, Simon; Lavigne, Régis; Rodriguez-Valera, Francisco; Sullivan, Matthew B; et al.(2019). Numerous cultivated and uncultivated viruses encode ribosomal proteins.. Nature communications, 10(1), 752. doi: 10.1038/s41467-019-08672-6. Lawrence Berkeley National Laboratory: Retrieved from: http://www.escholarship.org/uc/item/8f0519r0
Viruses modulate ecosystems by directly altering host metabolisms through auxiliary metabolic genes. However, viral genomes are not known to encode the core components of translation machinery, such as ribosomal proteins (RPs). Here, using reference
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
The gut microbiome harbors a ‘silent reservoir’ of antibiotic resistance (AR) genes that is thought to contribute to the emergence of multidrug-resistant pathogens through horizontal gene transfer (HGT). To counteract the spread of AR, it is para
Autor:
Aaron M. New, Ben Lehner
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
instname
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications
We lack an understanding of how the full range of genetic variants that occur in individuals can interact. To address this shortcoming, here we combine diverse mutations between genes in a model regulatory network, the galactose (GAL) switch of buddi
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Plants synthesize numerous ecologically specialized, lineage-specific metabolites through biosynthetic gene duplication and functional specialization. However, it remains unclear how duplicated genes are wired into existing regulatory networks. We sh