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pro vyhledávání: '"Ye Zheng"'
Autor:
Johan Auwerx, Ying Cui, Ruth T. Yu, Ronald M. Evans, Jianrong Wang, Hui Xiao, Caroline Zhang, Shuo Zhang, Annette R. Atkins, Ye Zheng, Na Zhang, Ruihong Zhu, Nanhai He, Michael Downes, Dexian Quan, Christopher Liddle, Qibin Leng, Chunhui Yang
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications
Nature Communications
Thymocytes must pass both positive and negative selections to become mature T cells. Negative selection purges thymocytes whose T-cell receptors (TCR) exhibit high affinity to self-peptide MHC complexes (self pMHC) to avoid autoimmune diseases, while