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Autor:
Lingchong You, Teng Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications
Nature Communications
Conjugative plasmids can mediate the spread and maintenance of diverse traits and functions in microbial communities. This role depends on the plasmid’s ability to persist in a population. However, for a community consisting of multiple populations
Autor:
Jean Soulier, Alain Sarasin, Ismael Padioleau, Andrey A. Yurchenko, Bakhyt T. Matkarimov, Sergey Nikolaev
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Recent studies demonstrated a dramatically increased risk of leukemia in patients with a rare genetic disorder, Xeroderma Pigmentosum group C (XP-C), characterized by constitutive deficiency of global genome nucleotide excision repair (GG-NER). The g
Autor:
Hu, Yuanyuan, Cronan, John E.
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Pimelic acid, a seven carbon α,ω-dicarboxylic acid (heptanedioic acid), is known to provide seven of the ten biotin carbon atoms including all those of the valeryl side chain. Distinct pimelate synthesis pathways were recently elucidated in Escheri
Autor:
Jonathan S. Abebe, Alexa B. R. McIntyre, Matthew D. Weitzman, Alexander M. Price, Nandan S. Gokhale, Christopher E. Mason, Daniel P. Depledge, Ashley N. Della Fera, Katharina E. Hayer, Stacy M. Horner, Angus C. Wilson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Adenovirus is a nuclear replicating DNA virus reliant on host RNA processing machinery. Processing and metabolism of cellular RNAs can be regulated by METTL3, which catalyzes the addition of N6-methyladenosine (m6A) to mRNAs. While m6A-modified adeno
Autor:
Sophia Maund, Russell Bainer, Thomas Januario, Subhra Chaudhuri, Tharu M. Fernando, Robert Piskol, Huong Trinh, Robert L. Yauch, Ethan Sokol, Zora Modrusan, Sally E. Trabucco, Marc Kschonsak, Qing Zhang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Nature Communications
Nature Communications
Genomic studies performed in cancer patients and tumor-derived cell lines have identified a high frequency of alterations in components of the mammalian switch/sucrose non-fermentable (mSWI/SNF or BAF) chromatin remodeling complex, including its core
Autor:
João Mello-Vieira, Maria M. Mota, Vanessa Zuzarte-Luis, Tania F. de Koning-Ward, Francisco J. Enguita
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Nature Communications
© The Author(s) 2020. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriat
Autor:
Yucen C. Huang, Zhiyong Lou, Mingyu Li, Tao Wang, Litao Zheng, Ji Ge, Ying Zhang, Zihe Rao, Zhihui Jia, Haofeng Wang, Quan Wang, Yan Gao, Liming Yan
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-6 (2020)
Nature Communications
Nature Communications
Non-structural proteins (nsp) constitute the SARS-CoV-2 replication and transcription complex (RTC) to play a pivotal role in the virus life cycle. Here we determine the atomic structure of a SARS-CoV-2 mini RTC, assembled by viral RNA-dependent RNA
Genome of Solanum pimpinellifolium provides insights into structural variants during tomato breeding
Autor:
Zhangjun Fei, Lei Gao, Samantha Mainiero, Chen Jiao, James J. Giovannoni, Susan R. Strickler, Julia Vrebalov, Lukas A Mueller, Stefanos Stravoravdis, Xin Wang, Shan Wu, Carmen Catalá, Jing Zhang, Gregory B. Martin, Prashant S. Hosmani, Surya Saha
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature Communications
Solanum pimpinellifolium (SP) is the wild progenitor of cultivated tomato. Because of its remarkable stress tolerance and intense flavor, SP has been used as an important germplasm donor in modern tomato breeding. Here, we present a high-quality chro
Autor:
Mei Zhang, Jeffrey Ross-Ibarra, Nathan M. Springer, Han Liu, Gen Xu, Dafang Wang, Qing Li, Jinliang Yang, Jing Lyu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
DNA methylation is a ubiquitous chromatin feature, present in 25% of cytosines in the maize genome, but variation and evolution of the methylation landscape during maize domestication remain largely unknown. Here, we leverage whole-genome sequencing
Autor:
Ashutosh Tripathy, Deepa Ajit, Natallia V. Riddick, John Q. Trojanowski, Michelle S. Itano, Sheryl S. Moy, Hanna Trzeciakiewicz, Todd J. Cohen, Zarin Tabassum, Youjun Chen, Claire Peterson, Rebecca Lobrovich, Jui-Heng Tseng, Aditi Ajit, Virginia M.-Y. Lee, David J. Irwin
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Tauopathies including Alzheimer’s disease (AD) are marked by the accumulation of aberrantly modified tau proteins. Acetylated tau, in particular, has recently been implicated in neurodegeneration and cognitive decline. HDAC6 reversibly regulates ta