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Autor:
Noora Aho, Mårten Wikström, Vladislav Grigorjev, Vineta Fellman, Vivek Sharma, Janne Purhonen, Artur Osyczka, Robert Ekiert, Jukka Kallijärvi, Rafał Pietras, Katarina Truvé, Jayasimman Rajendran
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications
Nature Communications
We previously observed an unexpected fivefold (35 vs. 200 days) difference in the survival of respiratory chain complex III (CIII) deficient Bcs1lp.S78G mice between two congenic backgrounds. Here, we identify a spontaneous homoplasmic mtDNA variant