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Autor:
Wah Chin Boon, Evan R. Simpson, Margaret E. E. Jones, Kerry J. McInnes, Laura Maffei, Cesare Carani
Publikováno v:
Nature clinical practice. Endocrinologymetabolism. 3(5)
Aromatase deficiency is rare in humans. Affected individuals cannot synthesize endogenous estrogens. Aromatase is the enzyme that catalyzes conversion of androgens into estrogens, and if aromatase is nonfunctional because of an inactivating mutation,