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pro vyhledávání: '"Anna M. Krichevsky"'
Autor:
Xandra O. Breakefield, Dimphna H. Meijer, Miguel Sena-Esteves, Anna M. Krichevsky, T. Wurdinger, Bob S. Carter, William T. Curry, van Rijn S, Gainche L, Johan Skog
Publikováno v:
Nature cell biology
Nature Cell Biology, 10(12), 1470-1479. Nature Publishing Group
Skog, J, Würdinger, T, van Rijn, S, Meijer, D H, Gainche, L, Sena-Esteves, M, Curry, W T, Carter, B S, Krichevsky, A M & Breakefield, X O 2008, ' Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers ', Nature Cell Biology, vol. 10, no. 12, pp. 1470-1479 . https://doi.org/10.1038/ncb1800
Nature Cell Biology, 10(12), 1470-1479. Nature Publishing Group
Skog, J, Würdinger, T, van Rijn, S, Meijer, D H, Gainche, L, Sena-Esteves, M, Curry, W T, Carter, B S, Krichevsky, A M & Breakefield, X O 2008, ' Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers ', Nature Cell Biology, vol. 10, no. 12, pp. 1470-1479 . https://doi.org/10.1038/ncb1800
Glioblastoma tumour cells release microvesicles (exosomes) containing mRNA, miRNA and angiogenic proteins. These microvesicles are taken up by normal host cells, such as brain microvascular endothelial cells. By incorporating an mRNA for a reporter p