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Akademický článek
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Autor:
Guangming Wu, Xiaofei Zhang, Xiwei Wang, He Liu, Yingying Lin, Siyuan Lin, Jie Wang, Junjie Shi, Jiekai Chen, Yu-Li Zhao, Mingwei Gao, Lei Chang, Xichen Bao, Duanqing Pei, Jiangping He, Kaixin Wu, Jiadong Liu, Guan-Zheng Luo, Man Zhang, Yaping Chen, Lingmei Jin
Publikováno v:
Nature. 591:322-326
The RNA modification N6-methyladenosine (m6A) has critical roles in many biological processes1,2. However, the function of m6A in the early phase of mammalian development remains poorly understood. Here we show that the m6A reader YT521-B homology-do
Autor:
Giovanna Brusatin, Daniele Di Biagio, Stefano Giulitti, Francesca Zanconato, Matteo Fassan, Gianluca Sigismondo, Giusy Battilana, Jeroen Krijgsveld, Luca Azzolin, Mariaceleste Aragona, Michelangelo Cordenonsi, Lei Chang, Alessandro Gandin, Romy Lucon Xiccato, Tito Panciera, Stefano Piccolo
Publikováno v:
Nature
Inactivation of ARID1A and other components of the nuclear SWI/SNF protein complex occurs at very high frequencies in a variety of human malignancies, suggesting a widespread role for the SWI/SNF complex in tumour suppression1. However, the underlyin