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pro vyhledávání: '"Antrix Jain"'
Autor:
Thomas A. Cooper, Siddhartha Tyagi, Antrix Jain, Ido Golding, Thomas R. Webb, Xiang Zhang, Azin Sayad, Nicholas J. Neill, Lukas M. Simon, Mayra Orellana, Sarah J. Kurley, Tingting Sun, Tiffany Y.T. Hsu, Rocio Dominguez-Vidana, Samuel O. Skinner, Richard Marcotte, Benjamin G. Neel, Gloria V. Echeverria, Chandraiah Lagisetti, Kristen L. Karlin, Christopher S. Bland, Alexander Renwick, Thomas F. Westbrook, Joel R. Neilson, Kathleen A. Scorsone, Jessica D. Hartman, Ronald J. Bernardi, Sung Yun Jung, Chad A. Shaw
Publikováno v:
Nature. 525(7569)
MYC (also known as c-MYC) overexpression or hyperactivation is one of the most common drivers of human cancer. Despite intensive study, the MYC oncogene remains recalcitrant to therapeutic inhibition. MYC is a transcription factor, and many of its pr