Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Hua Zhang"'
Publikováno v:
Molecules
Volume 25
Issue 3
Molecules, Vol 25, Iss 3, p 717 (2020)
Volume 25
Issue 3
Molecules, Vol 25, Iss 3, p 717 (2020)
Histone deacetylases (HDACs) have been proved to be promising targets for the treatment of cancer, and five histone deacetylase inhibitors (HDACis) have been approved on the market for the treatment of different lymphomas. In our previous work, we de
Publikováno v:
Molecules
Volume 24
Issue 22
Volume 24
Issue 22
The anti-aging activity of many plant flavonoids, as well as their mechanisms of action, have been explored in the current literature. However, the studies on the synergistic effects between the different flavonoid compounds were quite limited in pre
Publikováno v:
Molecules
Volume 24
Issue 14
Molecules, Vol 24, Iss 14, p 2569 (2019)
Volume 24
Issue 14
Molecules, Vol 24, Iss 14, p 2569 (2019)
A series of novel coumarin-based hydroxamate derivatives were designed and synthesized as histone deacetylase inhibitors (HDACis). Selective compounds showed a potent HDAC inhibition with nM IC50 values, with the best compound (10e) being nearly 90 t
Autor:
Cheng-Shi Jiang, Yong-Xi Ge, Hongrui Tao, Zhi-Qiang Cheng, Kongkai Zhu, Yin-Yin Wang, Hua Zhang
Publikováno v:
Molecules
Volume 24
Issue 14
Molecules, Vol 24, Iss 14, p 2568 (2019)
Volume 24
Issue 14
Molecules, Vol 24, Iss 14, p 2568 (2019)
In this study, a series of selective butyrylcholinesterase (BChE) inhibitors was designed and synthesized from the structural optimization of hit 1, a 4-((3,4-dihydroisoquinolin-2(1H)-yl)methyl)benzoic acid derivative identified by virtual screening
Publikováno v:
Molecules
Molecules, Vol 24, Iss 10, p 1888 (2019)
Molecules, Vol 24, Iss 10, p 1888 (2019)
Phellinus linteus is a popular medicinal mushroom that is widely used in China, Korea, Japan, and other Asian countries. P. linteus comprises various bioactive components, such as polysaccharides, triterpenoids, phenylpropanoids, and furans, and has
Induction of Low Temperature Tolerance in Wheat by Pre-Soaking and Parental Treatment with Melatonin
Publikováno v:
Molecules
Volume 26
Issue 4
Molecules, Vol 26, Iss 1192, p 1192 (2021)
Volume 26
Issue 4
Molecules, Vol 26, Iss 1192, p 1192 (2021)
Low temperatures seriously depress germination and seedling establishment in wheat and it is of great significance to explore approaches to improve wheat tolerance to low temperatures. In this study, the effects of seed pre-soaking and parental treat