Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Yasuo Urata"'
Autor:
Jeong Heo, Ja-Der Liang, Chang Won Kim, Hyun Young Woo, I-Lun Shih, Tung-Hung Su, Zhong-Zhe Lin, So Young Yoo, Stanley Chang, Yasuo Urata, Pei-Jer Chen
Publikováno v:
Molecular Therapy.
Autor:
Toshiyoshi Fujiwara, Hiroshi Tazawa, Michael Bouvet, Shinji Miwa, Hiroyuki Kishimoto, Yasuo Urata, Robert M. Hoffman, Shuya Yano, Mako Yamamoto, Shunsuke Kagawa, Yukihiko Hiroshima, Makoto Toneri
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy, vol 23, iss 7
Fluorescence-guided surgery (FGS) of cancer is an area of intense current interest. However, although benefits have been demonstrated with FGS, curative strategies need to be developed. Glioblastoma multiforme (GBM) is one of the most invasive of can
Autor:
Masahiko Nishizaki, Shinji Kuroda, Takeshi Nagasaka, Yuuri Hashimoto, Yasuo Urata, Yasuhiro Shirakawa, Satoru Kikuchi, Hiroshi Tazawa, Robert M. Hoffman, Shunsuke Kagawa, Hiroyuki Kishimoto, Toshiyoshi Fujiwara
Publikováno v:
Molecular Therapy. 23(3):501-509
Currently, early gastrointestinal cancers are treated endoscopically, as long as there are no lymph node metastases. However, once a gastrointestinal cancer invades the submucosal layer, the lymph node metastatic rate rises to higher than 10%. Theref
Autor:
Yuuri Hashimoto, Toshiyoshi Fujiwara, Noriaki Tanaka, Shunsuke Kagawa, Yasuo Urata, Katsuyuki Nagai, Yuichi Watanabe, Hitoshi Kawamura, Toru Kojima
Publikováno v:
Molecular Therapy. 13
Malignant mesothelioma is an extraordinarily challenging disease to treat; however, locoregional virotherapy may be applicable for this aggressive disease because of the accessibility by intrapleural and/or intratumoral virus delivery. We previously
Autor:
Noriaki Tanaka, Masayoshi Hioki, Hiroyuki Kishimoto, Yasuo Urata, Yoshihiro Ikeda, Yuichi Watanabe, Fuminori Teraishi, Toshiyoshi Fujiwara, Toru Kojima, Ryo Sakai, Shunsuke Kagawa
Publikováno v:
Molecular Therapy. 13
Currently available methods for detection of tumors in vivo such as X-ray, computed tomography, ultrasonography, and magnetic resonance imaging are noninvasive and are well studied; the images, however, are not specific for tumors. Direct optical ima
Autor:
Toshiya Fujiwara, Yoshiko Shirakiya, Yoshihiro Ikeda, Yasuo Urata, Toru Kojima, Yuuri Hashimoto, Ryo Sakai, Futoshi Uno, Shunsuke Kagawa, Masayoshi Hioki, Yuichi Watanabe, Fuminori Teraishi
Publikováno v:
Molecular Therapy. 13:S248-S249
Cancer gene therapy and oncolytic virotherapy have been studied extensively. However, the clinical application is hampered by its weak anticancer activity. We constructed a replicating adenovirus (OBP-301, Telomelysin), in which the human telomerase
Autor:
Toshiya Fujiwara, Futoshi Uno, Yoshihiro Ikeda, Yuuri Hashimoto, Shunsuke Kagawa, Fuminori Teraishi, Toshiyoshi Fujiwara, Yuichi Watanabe, Noriaki Tanaka, Yasuo Urata, Ryo Sakai, Toru Kojima, Masayoshi Hioki
Publikováno v:
Molecular Therapy. 13:S114
Gene therapy was investigated as a promising treatment for cancer. However, low transduction efficiency limits the efficacy of gene therapy in clinics. We previously demonstrated that telomerase- specific replication-competent adenovirus (Telomelysin
Autor:
Yuuri Hashimoto, Toshiyoshi Fujiwara, Katsuyuki Nagai, Fuminori Teraishi, Yuichi Watanabe, Shunsuke Kagawa, Noriaki Tanaka, Hitoshi Kawamura, Yasuo Urata
Publikováno v:
Molecular Therapy. 13:S56
Background: We previously reported that an attenuated adenovirus (OBP-301, 'Telomelysin'), in which the hTERT promoter element drives expression of E1A and E1B genes linked with an IRES, could replicate in cancer cells, and causes selective lysis of