Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Bork P"'
Autor:
Sander Wuyts, Renato Alves, Maria Zimmermann‐Kogadeeva, Suguru Nishijima, Sonja Blasche, Marja Driessen, Philipp E Geyer, Rajna Hercog, Ece Kartal, Lisa Maier, Johannes B Müller, Sarela Garcia Santamarina, Thomas Sebastian B Schmidt, Daniel C Sevin, Anja Telzerow, Peter V Treit, Tobias Wenzel, Athanasios Typas, Kiran R Patil, Matthias Mann, Michael Kuhn, Peer Bork
Publikováno v:
Molecular Systems Biology, Vol 19, Iss 9, Pp n/a-n/a (2023)
Abstract Multi‐omics analyses are used in microbiome studies to understand molecular changes in microbial communities exposed to different conditions. However, it is not always clear how much each omics data type contributes to our understanding an
Externí odkaz:
https://doaj.org/article/fd802a62805b4d79ab0ef30a579c5470
Akademický článek
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Publikováno v:
Molecular Systems Biology, Vol 11, Iss 5, Pp n/a-n/a (2015)
Externí odkaz:
https://doaj.org/article/f96dedd0f6274ce58dfbd2556e6c7e1d
Autor:
Georg Zeller, Julien Tap, Anita Y Voigt, Shinichi Sunagawa, Jens Roat Kultima, Paul I Costea, Aurélien Amiot, Jürgen Böhm, Francesco Brunetti, Nina Habermann, Rajna Hercog, Moritz Koch, Alain Luciani, Daniel R Mende, Martin A Schneider, Petra Schrotz‐King, Christophe Tournigand, Jeanne Tran Van Nhieu, Takuji Yamada, Jürgen Zimmermann, Vladimir Benes, Matthias Kloor, Cornelia M Ulrich, Magnus vonKnebel Doeberitz, Iradj Sobhani, Peer Bork
Publikováno v:
Molecular Systems Biology, Vol 10, Iss 11, Pp n/a-n/a (2014)
Abstract Several bacterial species have been implicated in the development of colorectal carcinoma (CRC), but CRC‐associated changes of fecal microbiota and their potential for cancer screening remain to be explored. Here, we used metagenomic seque
Externí odkaz:
https://doaj.org/article/7a655535a8c4478489a0a22b61348cf4
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
Abstract Protein post‐translational modifications (PTMs) allow the cell to regulate protein activity and play a crucial role in the response to changes in external conditions or internal states. Advances in mass spectrometry now enable proteome wid
Externí odkaz:
https://doaj.org/article/136af1c029d34e2eb0529e677a99d226
Autor:
Murat Iskar, Georg Zeller, Peter Blattmann, Monica Campillos, Michael Kuhn, Katarzyna H Kaminska, Heiko Runz, Anne‐Claude Gavin, Rainer Pepperkok, Vera van Noort, Peer Bork
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
In pharmacology, it is crucial to understand the complex biological responses that drugs elicit in the human organism and how well they can be inferred from model organisms. We therefore identified a large set of drug‐induced transcriptional module
Externí odkaz:
https://doaj.org/article/9478002f54924c62a01731099796f2c2
Autor:
Alessandro Ori, Niccolò Banterle, Murat Iskar, Amparo Andrés‐Pons, Claudia Escher, Huy Khanh Bui, Lenore Sparks, Victor Solis‐Mezarino, Oliver Rinner, Peer Bork, Edward A Lemke, Martin Beck
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
To understand the structure and function of large molecular machines, accurate knowledge of their stoichiometry is essential. In this study, we developed an integrated targeted proteomics and super‐resolution microscopy approach to determine the ab
Externí odkaz:
https://doaj.org/article/d19969a76d3b45278d9f800f429e461a
Autor:
Michael Kuhn, Mumna Al Banchaabouchi, Monica Campillos, Lars Juhl Jensen, Cornelius Gross, Anne‐Claude Gavin, Peer Bork
Publikováno v:
Molecular Systems Biology, Vol 9, Iss 1, Pp n/a-n/a (2013)
Side effect similarities of drugs have recently been employed to predict new drug targets, and networks of side effects and targets have been used to better understand the mechanism of action of drugs. Here, we report a large‐scale analysis to syst
Externí odkaz:
https://doaj.org/article/d6c2ffd1a87a40f1b2e29e08094192a3
Autor:
Oriol Gallego, Matthew J Betts, Jelena Gvozdenovic‐Jeremic, Kenji Maeda, Christian Matetzki, Carmen Aguilar‐Gurrieri, Pedro Beltran‐Alvarez, Stefan Bonn, Carlos Fernández‐Tornero, Lars Juhl Jensen, Michael Kuhn, Jamie Trott, Vladimir Rybin, Christoph W Müller, Peer Bork, Marko Kaksonen, Robert B Russell, Anne‐Claude Gavin
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
Protein–metabolite networks are central to biological systems, but are incompletely understood. Here, we report a screen to catalog protein–lipid interactions in yeast. We used arrays of 56 metabolites to measure lipid‐binding fingerprints of 1
Externí odkaz:
https://doaj.org/article/f43378c8acc249edbcfa2446039a4d6c
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp n/a-n/a (2010)
The molecular understanding of phenotypes caused by drugs in humans is essential for elucidating mechanisms of action and for developing personalized medicines. Side effects of drugs (also known as adverse drug reactions) are an important source of h
Externí odkaz:
https://doaj.org/article/cc1c18b35b0a48a9be94f5a7f69ee71f