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pro vyhledávání: '"59"'
Autor:
Graham K. Murray, Hisham Ziauddeen, H.J. Taverne, J. Haarsma, Ian M. Goodyer, Teresa Katthagen, J.D. Griffin, Thomas J. Spencer, Kelly M. J. Diederen, C Miller, Paul C. Fletcher
Publikováno v:
Molecular Psychiatry
Haarsma, J, Fletcher, P, Griffin, J, Taverne, H, Ziauddeen, H, Spencer, T, Miller, C, Katthagen, T, Goodyear, I, Diederen, K & Murray, G 2020, ' Precision-weighting of cortical unsigned prediction error signals benefits learning, is mediated by dopamine, and is impaired in psychosis ', Molecular Psychiatry, vol. 0, no. 0, pp. 1-14 . https://doi.org/10.1038/s41380-020-0803-8
Haarsma, J, Fletcher, P, Griffin, J, Taverne, H, Ziauddeen, H, Spencer, T, Miller, C, Katthagen, T, Goodyear, I, Diederen, K & Murray, G 2020, ' Precision-weighting of cortical unsigned prediction error signals benefits learning, is mediated by dopamine, and is impaired in psychosis ', Molecular Psychiatry, vol. 0, no. 0, pp. 1-14 . https://doi.org/10.1038/s41380-020-0803-8
Recent theories of cortical function construe the brain as performing hierarchical Bayesian inference. According to these theories, the precision of prediction errors plays a key role in learning and decision-making, is controlled by dopamine and con
Akademický článek
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Autor:
Holmans, P. A.1, Riley, B.2, Pulver, A. E.3, Owen, M. J.1, Wildenauer, D. B.4,5, Gejman, P. V.6, Mowry, B. J.7, Laurent, C.8, Kendler, K. S.2, Nestadt, G.3, Williams, N. M.1, Schwab, S. G.4,9,10, Sanders, A. R.6, Nertney, D.7, Mallet, J.11, Wormley, B.2, Lasseter, V. K.3, O'Donovan, M. C.1, Duan, J.6, Albus, M.12
Publikováno v:
Molecular Psychiatry. Aug2009, Vol. 14 Issue 8, p786-795. 10p. 3 Charts, 1 Graph.
Autor:
Houenou, J.1,2,3,4,5, Wessa, M.1,2,3 michele.wessa@zi-mannheim.de, Douaud, G.6, Leboyer, M.4,5,7, Chanraud, S.1,2,3, Perrin, M.8, Poupon, C.8, Martinot, J.-L.1,2,3, Paillere-Martinot, M.-L.1,2,3,9
Publikováno v:
Molecular Psychiatry. Nov2007, Vol. 12 Issue 11, p1001-1010. 10p. 3 Color Photographs, 3 Charts.
Autor:
Maria Jalbrzikowski, Amy Lin, Ariana Vajdi, Vardui Grigoryan, Leila Kushan, Christopher R. K. Ching, Charles Schleifer, Rebecca A. Hayes, Stephanie A. Chu, Catherine A. Sugar, Jennifer K. Forsyth, Carrie E. Bearden
Publikováno v:
Molecular psychiatry, vol 27, iss 10
Probing naturally-occurring, reciprocal genomic copy number variations (CNVs) may help us understand mechanisms that underlie deviations from typical brain development. Cross-sectional studies have identified prominent reductions in cortical surface
Autor:
Gerd Meyer zu Hörste, Saskia Räuber, Tillmann Ruland, Tim Hahn, Andreas Schulte-Mecklenbeck, Sven G. Meuth, Jonathan Repple, Catharina C. Gross, Heinz Wiendl, Rebecca Kuelby, Udo Dannlowski, Nico Melzer, Michael Heming, Volker Arolt, Bernhard T. Baune
Publikováno v:
Molecular Psychiatry. 26:7661-7670
Psychotic disorders are common and disabling mental conditions. The relative importance of immune-related mechanisms in psychotic disorders remains subject of debate. Here, we present a large-scale retrospective study of blood and cerebrospinal fluid
Autor:
Chunyan, Luo, XueNan, Pi, Na, Hu, Xiao, Wang, Yuan, Xiao, Siyi, Li, John A, Sweeney, Jeffrey R, Bishop, Qiyong, Gong, Dan, Xie, Su, Lui
Publikováno v:
Molecular psychiatry. 26(11)
Epigenetic modifications are plausible molecular sources of phenotypic heterogeneity across schizophrenia patients. The current study investigated biological heterogeneity in schizophrenia using peripheral epigenetic profiles to delineate illness sub
Autor:
Stacy Miller, Raina Kumar, Charles R. Marmar, Marti Jett, Leroy Hood, Burook Misganaw, Seid Muhie, Duna Abu-Amara, Kerry J. Ressler, Kai Wang, Bernie J. Daigle, Rasha Hammamieh, Synthia H. Mellon, Inyoul Lee, Janine D. Flory, Aarti Gautam, Ruoting Yang, Derese Getnet, Kelsey R. Dean, Francis J. Doyle, Rachel Yehuda, Owen M. Wolkowitz
Publikováno v:
Molecular Psychiatry
Post-traumatic stress disorder (PTSD) is a heterogeneous condition evidenced by the absence of objective physiological measurements applicable to all who meet the criteria for the disorder as well as divergent responses to treatments. This study capi
Autor:
Karen L. Jones, Judith A Van de Water
Publikováno v:
Molecular Psychiatry. 24:252-265
It has been estimated that autism spectrum disorder (ASD) now affects 1 in 59 children in the United States. Although the cause(s) of ASD remain largely unknown, it is becoming increasingly apparent that ASD can no longer be defined simply as a behav
Autor:
Danyllo Oliveira, Fred H. Gage, Ernesto Goulart, Maria C. Marchetto, Thalita Figueiredo, Mayana Zatz, Gerson Shigeru Kobayashi, Shani Stern, Renata Santos, Ana P.D. Mendes, Fernando Kok, Danielle de Paula Moreira
Publikováno v:
Molecular Psychiatry
Molecular Psychiatry, Nature Publishing Group, 2020, Online ahead of print. ⟨10.1038/s41380-020-00862-9⟩
Molecular Psychiatry, Nature Publishing Group, 2020, Online ahead of print. ⟨10.1038/s41380-020-00862-9⟩
International audience; A homozygous mutation in the inositol monophosphatase 1 (IMPA1) gene was recently identified in nine individuals with severe intellectual disability (ID) and disruptive behavior. These individuals belong to the same family fro