Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Weihong Song"'
Autor:
Qing Zhang, Keenan Sterling, Lu Xu, Mengen Xing, Fang Cai, Sheng Yu, Isabel Bestard-Lorigados, Weihong Song
Publikováno v:
Molecular Neurobiology. 60:2455-2469
Publikováno v:
Molecular Neurobiology. 57:3150-3157
Alzheimer's disease (AD) is the most common neurodegenerative disease, and there has been no disease-modifying treatment for AD. Recent studies suggest that trehalose may have beneficial effect on neurodegenerative diseases through regulating autopha
Publikováno v:
Molecular Neurobiology. 55:1862-1870
Recent studies suggest that TMP21 is a selective modulator of γ-secretase and its dysregulation affects APP processing, leading to increased Aβ generation. However, the genetic association between Tmp21 and Alzheimer's disease (AD) remains elusive.
Autor:
Zhe Wang, Weihong Song, Weitao Zhou, Dandan Lou, Mengjiao Yu, Lingling Zheng, Daochao Huang, Fang Cai, Weihui Zhou, Shou Yang, Tingyu Li
Publikováno v:
Molecular neurobiology. 55(6)
The majority of Alzheimer’s disease (AD) cases are sporadic with unknown causes. Many dietary factors including excessive alcohol intake have been reported to increase the risk to develop AD. The effect of alcohol on cognitive functions and AD path
Publikováno v:
Molecular Neurobiology. 50:1085-1097
AD, a devastating neurodegenerative disorder, is the most common cause of dementia in the elderly. Patients with AD are characterized by three hallmarks of neuropathology including neuritic plaque deposition, neurofibrillary tangle formation, and neu
Autor:
Weihui Zhou, Daochao Huang, Weihong Song, Xiaoyong Li, Yi Feng, Yanhua Li, Yu Kang, Dandan Lou, Tingyu Li, Yan Xiang, Weitao Zhou
Publikováno v:
Molecular neurobiology. 54(6)
SET is elevated and mislocalized in the neuronal cytoplasm in brains of Alzheimer’s disease (AD) and Down syndrome (DS) patients. Cytoplasm SET leads to inhibition of protein phosphatase 2A and is involved in the tau pathology. However, the regulat
Autor:
Yili Wu, Wei Chen, Xiaoling Duan, Weihong Song, Xiaozhu Zhang, Shuting Zhang, Fang Cai, Haiyan Zou, Mingming Zhang
Publikováno v:
Molecular neurobiology. 51(2)
Down syndrome (DS) is one of the most common genetic diseases. Patients with DS display growth delay and intellectual disabilities and develop Alzheimer's disease (AD) neuropathology after middle age, including neuritic plaques and neurofibrillary ta
Publikováno v:
Molecular neurobiology. 51(1)
The macrophage migration inhibitory factor (MIF) is a multifaceted cytokine involved in many processes, including cellular responses to ischemia/reperfusion injury in the heart and brain. This study was undertaken to determine whether human MIF expre