Zobrazeno 1 - 10
of 18
pro vyhledávání: ''
Publikováno v:
Molecular Neurobiology. 58:4251-4267
Neuroinflammation can cause cognitive deficits, and preexisting neuroinflammation is observed frequently in the clinic after trauma, surgery, and infection. Patients with preexisting neuroinflammation often need further medical treatment under genera
Autor:
Ola A. Heikal, May A. Abd El Fattah, Mohammed F. El-Yamany, Yasmine A. Abdelhamid, Osama A. Badary
Publikováno v:
Molecular Neurobiology. 58:1504-1516
PPAR-γ anti-inflammatory functions have received significant attention since its agonists have been shown to exert a wide range of protective effects in many experimental models of neurologic diseases. Rice bran is very rich in polyunsaturated fatty
Publikováno v:
Molecular Neurobiology
The SARS-CoV-2 virus that is the cause of coronavirus disease 2019 (COVID-19) affects not only peripheral organs such as the lungs and blood vessels, but also the central nervous system (CNS)—as seen by effects on smell, taste, seizures, stroke, ne
Autor:
Carmela Giampà, Claudia Balducci, Vincenza D'Angelo, Luisa Artioli, Vladimiro Artuso, Emanuela Paldino, Pietro La Vitola, Gianluigi Forloni, Francesca Fusco
Publikováno v:
Molecular Neurobiology
Mechanisms of tissue damage in Huntington’s disease involve excitotoxicity, mitochondrial damage, and inflammation, including microglia activation. Immunomodulatory and anti-protein aggregation properties of tetracyclines were demonstrated in sever
Publikováno v:
Mol Neurobiol
Mitochondrial dysfunction and oxidative stress play a key role in ischemia/reperfusion (I/R) induced brain injury. We previously showed that ubiquilin-1 (Ubqln1), a ubiquitin-like protein, improves proteostasis and protects brains against oxidative s
Autor:
José L. M. Madrigal, Juan C. Leza, Marta González-Prieto, Irene L Gutiérrez, Javier R. Caso, Borja García-Bueno
Publikováno v:
Molecular Neurobiology. 56:8628-8642
The reduction of brain noradrenaline levels is associated to the initiation of Alzheimer's disease and contributes to its progression. This seems to be due mainly to the anti-neuroinflammatory actions of noradrenaline. The analysis of noradrenaline e
Autor:
Euler Esteves Ribeiro, Kennya Mota, Alencar Kolinski Machado, Diulie Valente de Souza, Francine Carla Cadoná, David Frederick Bodenstein, Tuyla Fontana, Carolina Bordin Davidson, Michele Rorato Sagrillo, Andiara Prates Ramos, Ana Cristina Andreazza, Mirian Salvador
Publikováno v:
Molecular neurobiology. 58(9)
Neurological disorders have been demonstrated to be associated with mitochondrial dysfunction. This impairment may lead to oxidative stress and neuroinflammation, specifically promoted by NLRP3 expression. Acai (Euterpe oleracea Mart.) has been studi
Autor:
Minglei Guo, Ashutosh Tripathi, Annadurai Thangaraj, Ernest T. Chivero, Shilpa Buch, Palsamy Periyasamy
Publikováno v:
Mol Neurobiol
Cocaine use disorder is a major health crisis that is associated with increased oxidative stress and neuroinflammation. While the role of NLRP3 inflammasome in mediating neuroinflammation is well-recognized, whether cocaine induces this response rema
Autor:
Ariandne Oliveira Marques, Francielle Mina, Gustavo Luis Schiavo, Natália Quadros Magnus, Júlia Matias Carollo Macieski, Michelle Lima Garcez, Josiane Budni, Tatiani Bellettini-Santos, Aline Pereira da Luz, Eduarda Behenck Medeiros
Publikováno v:
Molecular Neurobiology. 56:2606-2617
Alzheimer’s disease (AD) is a neurodegenerative disease which is characterized by progressive memory loss, the accumulation of β-amyloid peptide (Aβ) (mainly Aβ1-42), and more recently, by neuroinflammation, which has been highlighted as playing
Beneficial Effects of the Calcium Channel Blocker CTK 01512-2 in a Mouse Model of Multiple Sclerosis
Autor:
Rodrigo B. M. Silva, Maria M. Campos, Samuel Greggio, Jaderson Costa da Costa, Gianina Teribele Venturin, Marcus Vinicius Gomez
Publikováno v:
Molecular Neurobiology. 55:9307-9327
Voltage-gated calcium channels (VGCCs) play a critical role in neuroinflammatory diseases, such as multiple sclerosis (MS). CTK 01512-2 is a recombinant version of the peptide Phα1β derived from the spider Phoneutria nigriventer, which inhibits N-t