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Autor:
Tucker A. Patterson, Charles M. Fogle, Joseph P. Hanig, Shuliang Liu, William Slikker, Fang Liu, Cheng Wang
Publikováno v:
Molecular neurobiology. 57(1)
Early life exposure to general anesthetics can have neurotoxic consequences. Evidence indicates that xenon, a rare noble gas with anesthetic properties, may lessen neuronal damage under certain conditions. However, its potential neuroprotective prope
Publikováno v:
Molecular neurobiology. 56(11)
Chemotherapy-induced peripheral neuropathy (CIPN) adversely impacts quality of life and a challenge to treat with existing drugs used for neuropathic pain. Losartan, an angiotensin II type 1 receptor (AT1R) antagonist widely used to treat hypertensio
Autor:
Emilio L. Streck, André Felipe Rodrigues, Carlos Alexandre Netto, Matheus Grunevald, Letícia Ferreira Pettenuzzo, Angela T. S. Wyse, Paula Pierozan, Felipe Schmitz, Giselli Scaini, Helena Biasibetti
Publikováno v:
Molecular Neurobiology. 54:4201-4216
Although the use, and misuse, of methylphenidate is increasing in childhood and adolescence, there is little information about the consequences of this psychostimulant chronic use on brain and behavior during development. The aim of the present study
Autor:
Chuansheng Zhao, Wenping Ma, Huibin Wang, Jukka Jolkkonen, Wangshu Xu, Chengguang Song, Xiaopeng Mu
Publikováno v:
Molecular Neurobiology. 54:2406-2414
Bumetanide, a selective Na+-K+-Cl−-co-transporter inhibitor, is widely used in clinical practice as a loop diuretic. In addition, bumetanide has been reported to attenuate ischemia-induced cerebral edema and reduce neuronal injury. This study exami
Autor:
Mohammad Taghi Joghataei, Sonja Johann, Soraya Mehrabi, Adib Zendedel, Markus Kipp, Gholamreza Hassanzadeh, Cordian Beyer
Publikováno v:
Molecular neurobiology. 53(5)
Stromal cell-derived factor-1 alpha (SDF-1a) or CXCL12 is an important cytokine with multiple functions in the brain during development and in adulthood. The inflammatory response initiated by spinal cord injury (SCI) involves the processing of inter
Publikováno v:
Molecular neurobiology. 53(7)
Overexpression of cellular prion protein, PrP(C), has cytoprotective effects against neuronal injuries. Inhibition of cell death-associated proteases such as necrosis-linked calpain and apoptosis-linked caspase are also neuroprotective. Here, we syst