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Autor:
Carmen Infante-Garcia, Yaiza Garcia-Molina, Juan Jose Ramos-Rodriguez, Monica Garcia-Alloza, Alfonso M. Lechuga-Sancho, Lucia Galindo-Gonzalez
Publikováno v:
Molecular Neurobiology
Alzheimer’s disease (AD) and vascular dementia (VaD) are the most common causes of dementia, and borderlines are blurred in many cases. Aging remains the main risk factor to suffer dementia; however, epidemiological studies reveal that diabetes may
Autor:
Gabriel Rodrigo Fries, Robson Coutinho-Silva, Flávio Kapczinski, Ana Maria Oliveira Battastini, Bianca Pfaffenseller, Carolina Gubert, Pâmela Ferrari, Fernanda Bueno Morrone
Publikováno v:
Molecular neurobiology. 53(1)
The objective of this study was to explore the association between the P2X7 purinergic receptor (P2X7R) and neuroinflammation using a preclinical model of acute bipolar mania. We analyzed the modulatory effects of P2X7R agonist (3'-O-(4-benzoyl)benzo
Autor:
Juan Jose Ramos-Rodriguez, Eleanor K. Pickett, Rosemary J. Jackson, Esperanza Ortegon, Carmen Infante-Garcia, Tara L. Spires-Jones, Fernando Hernandez-Pacho, Carmen Hierro-Bujalance, Monica Garcia-Alloza
Publikováno v:
Molecular Neurobiology
Infante-Garcia, C, Ramos-Rodriguez, J J, Hierro-Bujalance, C, Ortegon, S, Pickett, E, Jackson, R, Hernandez-Pacho, F, Spires-Jones, T & Garcia-Alloza, M 2017, ' Antidiabetic polypill improves central pathology and cognitive impairment in a mixed model of Alzheimer's disease and type 2 diabetes ', Molecular Neurobiology . https://doi.org/10.1007/s12035-017-0825-7
Infante-Garcia, C, Ramos-Rodriguez, J J, Hierro-Bujalance, C, Ortegon, S, Pickett, E, Jackson, R, Hernandez-Pacho, F, Spires-Jones, T & Garcia-Alloza, M 2017, ' Antidiabetic polypill improves central pathology and cognitive impairment in a mixed model of Alzheimer's disease and type 2 diabetes ', Molecular Neurobiology . https://doi.org/10.1007/s12035-017-0825-7
Type 2 diabetes (T2D) is an important risk factor to suffer dementia, being Alzheimer's disease (AD) as the most common form. Both AD and T2D are closely related to aging and with a growing elderly population it might be of relevance to explore new t