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Autor:
Zeyu Zhu, Zhipeng Li, Zhigang Wang, Ying Wang, Xinyuan Zhou, Yuhua Bao, Yanjun Wang, Weibing Li
Publikováno v:
Molecular Medicine Reports
Colon carcinoma is one of the most common cancers worldwide. Epidemiological studies have revealed that colon cancer is the third leading cause of cancer-related deaths, which is due to the increased incidence and mortality rates. However, the treatm
Publikováno v:
Molecular Medicine Reports
Mounting evidence has indicated that circular RNAs (circRNAs) serve essential roles in the tumorigenesis and development of various types of cancer. However, the biological functions and the underlying mechanisms of circRNAs in breast cancer (BC) rem
Publikováno v:
Molecular Medicine Reports
MicroRNA (miR)-4306 and FoxD2-adjacent opposite strand RNA 1 (FOXD2-AS1) are cancer-related genes involved in tumor progression. However, the potential functional roles of miR-4306 and FoxD2-AS1 in colorectal cancer (CRC) development remain unknown.
Publikováno v:
Molecular Medicine Reports. 24
It has been reported that microRNA (miRNA/miR)‑25 is downregulated in patients with intervertebral disc degeneration (IVDD). However, the potential role of miR‑25 in IVDD remains unclear. Therefore, the present study aimed to investigate the effe
Autor:
Victor Trevino, Elsa N Garza-Treviño, Paulina Delgado-Gonzalez, Rocio Ortiz-Lopez, Orlando Solís-Coronado, Jose F Islas-Cisneros, Salvador Said-Fernández, Herminia G. Martínez-Rodríguez, Adriana G. Quiroz-Reyes, Adolfo Soto-Domínguez, Gerardo R. Padilla-Rivas
Publikováno v:
Molecular Medicine Reports
Colorectal cancer (CRC) is one of the main causes of mortality. Recent studies suggest that cancer stem cells (CSCs) can survive after chemotherapy and promote tumor invasiveness and aggression. According to a higher hierarchy complexity of CSC, diff
Publikováno v:
Molecular Medicine Reports. 24
Osteoporosis is a severe bone disease commonly occurring in older males and postmenopausal females. Previous studies have shown that long non‑coding (lnc)RNA growth arrest‑specific 5 (GAS5) serves an important role in osteoporosis. However, its r
Autor:
Guolin Shi, Jin Wu, Jinyuan Yan, Qingchun Lei, Yingxia Guan, Tingting Wu, Xiaogang Hu, Ying Wang
Publikováno v:
Molecular Medicine Reports
Parkinson's disease (PD) is the second most common neurodegenerative disease amongst the middle‑aged and elderly populations. Several studies have confirmed that the microbiota‑gut‑brain axis (MGBA) serves a key role in the pathogenesis of PD.
Autor:
Lin Lv, Ke Zhan, Zhechuan Mei, Yang Bai, Shengtao Liao, Liewang Qiu, Lili Kuang, Qingqing Luo, Hongyu Chen
Publikováno v:
Molecular Medicine Reports
Hepatocellular carcinoma (HCC) is one of the most common types of cancer, which is associated with a poor prognosis. It is necessary to identify novel prognostic biomarkers and therapeutic targets to improve the survival of patients with HCC. In the
Publikováno v:
Molecular Medicine Reports. 24
Multiple myeloma (MM) is a malignancy of plasma cells that leads to marrow failure and bone lesions. Numerous studies have verified the link between long non‑coding RNAs (lncRNAs) and MM. The present study aimed to examine the role and underlying m
Publikováno v:
Molecular Medicine Reports
Long non‑coding RNAs (lncRNAs) have been shown to function as crucial regulators in the progression of various types of cancer, including nasopharyngeal carcinoma (NPC). The aim of the present study was to investigate the mechanisms underlying the