Zobrazeno 21 - 30
of 1 196
pro vyhledávání: ''
Autor:
Hu Yiren, Wu Chen, Chen Dake, Rui Feng, Li Linjin, Bao Wenshuo, Xiaomin Xu, Chen Heyi, Zhu Jianlong
Publikováno v:
Molecular Medicine Reports
Prostate cancer (PCa) endangers the life and health of older men. Most PCa cases develop into castration‑resistant PCa (CRPC) within 2 years. At present, the molecular mechanisms of the occurrence and development of PCa and its transformation to CR
Publikováno v:
Molecular Medicine Reports
Cataract is a blinding‑caused disease and affects millions of individuals worldwide. Although conventional phacoemulsification (CPCS) has been widely used for treatment of cataract, the incidence of cataract‑caused blindness still increased year
Publikováno v:
Molecular Medicine Reports
Long non‑coding RNA high expression in hepatocellular carcinoma (lncRNA HEIH) acts as an oncogene in multiple tumors, including hepatocellular carcinoma, colorectal cancer, melanoma and non‑small cell lung cancer. However, the role of HEIH in bre
Publikováno v:
Molecular Medicine Reports
Medullary thyroid carcinoma (MTC) is a relatively rare subtype of thyroid cancer, accounting for 5‑10% of all cases of thyroid cancer worldwide. Due to the current lack of knowledge regarding the tumorigenesis of MTC, the clinical treatment of MTC
Publikováno v:
Molecular Medicine Reports
MicroRNA (miRNA/miR)‑92a has been identified as being significantly downregulated in non‑small cell lung cancer (NSCLC) tissues using a miRNA array. However, its biological function and molecular mechanisms in NSCLC have not been fully elucidated
Publikováno v:
Molecular Medicine Reports
Growth arrest‑specific 5 (GAS5) is a known tumor suppressor which negatively regulates cell survival and malignancy in several cancer cell types. The present study aimed to establish the correlation between GAS5 and unc‑51 like autophagy activati
Publikováno v:
Molecular Medicine Reports
Pancreatic cancer (PC) is the fourth most common cause of cancer‑related mortality worldwide and is characterized by high invasiveness and early metastasis. To identify novel diagnostic markers, the present study aimed to understand the mechanism u
Autor:
Qiuxia Xiong, Xiulin Jiang, Songqing Fan, Juan Wang, Chuanjiang Chen, Chunyan Xiong, Baiyang Liu, Qingyuan Tao, Hui Zhang, Yong Duan, Lincan Duan, Xiaobo Chen
Publikováno v:
Molecular Medicine Reports
Lung cancer has a high mortality rate worldwide. Non‑SMC condensin I complex subunit H (NCAPH) has been identified to be one of the regulatory subunits of the condensin I complex, which is essential for the correct packaging and segregation of chro
Publikováno v:
Molecular Medicine Reports
Hepatocellular carcinoma (HCC) was the third most common cause of cancer-associated mortality in China in 2015. Early detection of HCC and hepatic cirrhosis (HC) can serve a crucial role in the prevention and therapeutic intervention of these disease
Upregulated microRNA-330-3p promotes calcification in the bicuspid aortic valve via targeting CREBBP
Autor:
Chen Su, Haoliang Sun, Buqing Ni, Jiaxi Gu, Junjie Du, Rui Zheng, Yaojun Guo, Yongfeng Shao, Hao Liu, Keshuai He
Publikováno v:
Molecular Medicine Reports
One key risk factor of aortic valve stenosis in clinical practice is bicuspid aortic valve (BAV). Increasing evidence indicates that numerous microRNAs (miRs/miRNAs) are involved in BAV calcification via their target genes. miR‑330‑3p was found t