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Publikováno v:
Molecular Medicine Reports
MicroRNA-3666 (miR-3666) acts as a tumor suppressor in cervical cancer, non-small cell lung cancer and thyroid carcinoma; however, the function of miR-3666 in colorectal cancer (CRC) remains largely unknown. In the present study, was demonstrated tha
Publikováno v:
Molecular Medicine Reports.
MicroRNA (miRNA/miR)-124 is a miRNA, which exerts tumor suppressive effects but is frequently absent in tumors. Although it has been validated to target oncogenic genes such as signal transducer and activator of transcription 3, forkhead box Q1, and
Autor:
Fengmei Li, Hainian Xu
Publikováno v:
Molecular Medicine Reports
Myocardial failure has a negative impact on the quality of human life. MicroRNA (miR) expression abnormalities lead to the development of many pathological conditions, including myocardial failure, and therefore the present study primarily focused on
Publikováno v:
Molecular Medicine Reports
Epidermal growth factor receptor pathway substrate 8 (Eps8) has been identified as a novel substrate for epidermal growth factor receptor (EGFR) kinase and is involved in EGFR-mediated signaling pathways correlated with tumorigenesis, proliferation a
Publikováno v:
Molecular Medicine Reports. 14:2657-2664
The expression of microRNA (miR)-610 has previously been reported to be downregulated in gastric cancer and hepatocellular carcinoma. However, miR-610 has yet to be investigated in human glioma. In the present study, miR-610 expression was analyzed b
Autor:
Joon Kyoo Lee, Tae Mi Yoon, Young Eun Joo, Sang Chul Lim, Sun‑Ae Kim, Ik Joo Chung, Young‑Lan Park, Dong Hoon Lee
Publikováno v:
Molecular Medicine Reports. 14:515-520
Livin, a member of the human inhibitor of apoptosis protein (IAP) family, is expressed at high levels in various human cancer tissues and may have prognostic significance. The aim of the present study was to evaluate the effect of Livin on tumor cell
Publikováno v:
Molecular Medicine Reports. 14:537-543
MicroRNA-23b (miR-23b) is important in tumor proliferation and metastasis. In this study, it was suggested that the levels of miR-23b were increased in nasopharyngeal carcinoma (NPC) tissues compared with the adjacent normal tissues. The present stud
Autor:
Yaoting Gui, Yifan Li, Yuchi Li, Tiantian Wang, Shangqi Yang, Xiangming Mao, L U Jin, Zuhu Yu, Duqun Chen, Yongqing Lai, Liangchao Ni
Publikováno v:
Molecular Medicine Reports. 13:3326-3334
Renal cell carcinoma (RCC) is the most common type of kidney cancer in adults, which is associated with poor prognosis and high recurrence. Long non‑coding RNAs (lncRNAs) have been reported to be dysregulated in cancer and to be important in the re
Publikováno v:
Molecular Medicine Reports. 13:2769-2776
The present study aimed to determine the effect of microRNA (miR)‑210 on osteoarthritis (OA). The expression levels of miR‑210, type I and X collagen (COL1A1 and COL10A1) and matrix metallopeptidase 13 (MMP13) in OA and normal chondrocytes were d
Autor:
Yun‑Min Lu, Yuan‑Fei Liu, Yuan Liu, Xiao‑Hong Liao, Wu‑Ming Kong, Guo‑Qiang Qu, Wei-Xiong Chen
Publikováno v:
Molecular Medicine Reports
Gastric cancer (GC) is the second most common cause of cancer-associated mortality worldwide. Previous studies suggest that mitogen-activated protein kinase kinase kinase kinase isoform 4 (MAP4K4) is involved in cancer cell growth, apoptosis and migr