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Publikováno v:
Molecular Medicine Reports
Sepsis is a serious clinical condition characterized by systemic inflammation. The long noncoding RNA (lncRNA) highly upregulated in liver cancer (HULC) was validated to partake in the development of sepsis. The present study aimed to investigate the
Publikováno v:
Molecular Medicine Reports
The present study aimed to explore the biological functions and molecular mechanisms of the long non‑coding RNA VIM antisense RNA 1 (VIM‑AS1) in gastric cancer (GC). The expression of VIM‑AS1 was analyzed in tissues from patients with GC and GC
Publikováno v:
Molecular Medicine Reports
Alterations in microRNA (miRNA/miRs) expression are associated with the occurrence and course of human diseases, including chronic lymphocytic leukemia (CLL). Expression of miRNAs may vary among patients with CLL in different cytogenetic risk groups.
Autor:
Wakako Nonaka, Tadayuki Takata, Hisakazu Iwama, Satoshi Komatsubara, Hideki Kobara, Masaki Kamada, Kazushi Deguchi, Tetsuo Touge, Osamu Miyamoto, Takehiro Nakamura, Toshifumi Itano, Tsutomu Masaki
Publikováno v:
Molecular Medicine Reports
Progressive supranuclear palsy (PSP) is a neurodegenerative tauopathy described as a syndrome of postural instability, supranuclear vertical gaze palsy, dysarthria, dystonic rigidity of the neck and trunk, dementia, and pseudobulbar palsy. The clinic
Publikováno v:
Molecular Medicine Reports
Medullary thyroid carcinoma (MTC) is a relatively rare subtype of thyroid cancer, accounting for 5‑10% of all cases of thyroid cancer worldwide. Due to the current lack of knowledge regarding the tumorigenesis of MTC, the clinical treatment of MTC
Publikováno v:
Molecular Medicine Reports
MicroRNA (miRNA/miR)‑92a has been identified as being significantly downregulated in non‑small cell lung cancer (NSCLC) tissues using a miRNA array. However, its biological function and molecular mechanisms in NSCLC have not been fully elucidated
Upregulated microRNA-330-3p promotes calcification in the bicuspid aortic valve via targeting CREBBP
Autor:
Chen Su, Haoliang Sun, Buqing Ni, Jiaxi Gu, Junjie Du, Rui Zheng, Yaojun Guo, Yongfeng Shao, Hao Liu, Keshuai He
Publikováno v:
Molecular Medicine Reports
One key risk factor of aortic valve stenosis in clinical practice is bicuspid aortic valve (BAV). Increasing evidence indicates that numerous microRNAs (miRs/miRNAs) are involved in BAV calcification via their target genes. miR‑330‑3p was found t
Publikováno v:
Molecular Medicine Reports. 22:2085-2092
Pancreatic cancer is a fatal disease with a high mortality rate and poor prognosis worldwide. The aberrant expression of microRNAs (miRs) is associated with cancer development and progression. The present study aimed to evaluate the functional role o
Publikováno v:
Molecular Medicine Reports
Osteoporosis is a complex multifactorial disorder characterized by microarchitectural deterioration, low bone mass, and increased risk of fractures or broken bones. Balanced bone remodeling is tightly regulated by the differentiation, activity and ap
Publikováno v:
Molecular Medicine Reports
MicroRNAs (miRNAs/miRs) are small noncoding RNAs 19‑24 nucleotides in length, which can play an important role in tumor development. However, the influence of miRNAs on the tumorigenicity of ovarian cancer cells has not been fully elucidated. Previ