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Publikováno v:
Molecular Medicine Reports. 16:9143-9148
Gastric cancer (GC) is one of the major leading causes of cancer‑associated mortality worldwide. Serum biomarkers have a vital role in diagnosis and prognosis of GC, and interleukin (IL)‑16 may serve as a useful biomarker with prognostic value fo
Publikováno v:
Molecular Medicine Reports
Gastric cancer is one of the most common cancers and the second leading cause of cancer‑associated mortality worldwide. Recurrence, metastasis and resistance to drug treatment are the main barrier to survival of patients with advanced stage gastric
Autor:
Zhi‑Hua Ye, Xiao‑Liang Huang, Gang Chen, Jian-Jun Li, Hong Yang, Chu‑Mei Zeng, Yi‑Qiang Jiang, Dong‑Yue Wen, Hua Ding, Jie Mo, Xiao‑Yong Cai
Publikováno v:
Molecular Medicine Reports
The clinical significance of microRNA (miR)-136-5p in hepatocellular carcinoma (HCC) has not been verified. Therefore, in the current study, the authors aimed to explore miR-136-5p expression and its clinical significance in HCC, as well as to invest
Autor:
Hou‑Quan Tao, Jun‑Gang Luo, Xujun He, Jian‑Zhong Chen, Shi‑Bin Jiang, Xiao‑Ting Jiang, Zheng‑Chuang Liu, Ying‑Jie Xia, Liang Wang
Publikováno v:
Molecular Medicine Reports. 16:6882-6889
Prolyl hydroxylase 3 (PHD3) is widely accepted as a tumor suppressor; however, the expression of PHD3 in various cancer types remains controversial. The present study aimed to investigate the association between PHD3 expression and the clinicopatholo
Publikováno v:
Molecular Medicine Reports. 16:2113-2120
Lung cancer is the primary cause of cancer‑associated mortality in men and women worldwide. Increasing evidence indicates that abnormal microRNA (miRNA) expression contributes to the carcinogenesis and progression of multiple human cancers, includi
Autor:
Fengmei Li, Hainian Xu
Publikováno v:
Molecular Medicine Reports
Myocardial failure has a negative impact on the quality of human life. MicroRNA (miR) expression abnormalities lead to the development of many pathological conditions, including myocardial failure, and therefore the present study primarily focused on
Publikováno v:
Molecular medicine reports. 16(4)
Gastric cancer is the fourth most common malignancy and the third leading cause of cancer‑associated deaths worldwide. It has previously been demonstrated that microRNAs (miRNAs) are actively involved in the pathogenesis of gastric cancer. Therefor
Publikováno v:
Molecular medicine reports. 16(6)
Ovarian cancer (OC) is the fifth leading cause of cancer‑associated mortality among women in developed countries. Numerous microRNAs are aberrantly expressed in epithelial (E) OC, and are involved in EOC formation and progression. As such, microRNA
Publikováno v:
Molecular Medicine Reports
Although certain biomarkers that are directly associated with the overall survival (OS) of patients with pancreatic adenocarcinoma (PAAD) have been identified, the efficacy of a single factor is limited to predicting the prognosis. The aim of the pre
Autor:
Xue‑Feng Hu, Jian‑Chun Su
Publikováno v:
Molecular medicine reports. 16(4)
Breast cancer is one of the most frequently occurring malignancies in female cancers worldwide, however, its detailed mechanism of tumorigenesis remains to be elucidated. Long non-coding RNAs (LncRNAs) have previously been demonstrated to be importan