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Autor:
Ovidiu Zlatian, Izotov Bn, Anca Ungureanu, Tiberiu Ţîrcă, Ramona Cioboată, Alice Elena Găman, Cristina Dehelean, Andrei Ioan Drocaş, Anca Oana Docea, Valerii N. Rakitskii, Demetrios A. Spandidos, Aristides M. Tsatsakis, George Mitroi, Daniela Calina
Publikováno v:
Molecular Medicine Reports
Staphylococcus aureus (SA or S. aureus) is a common pathogen that leads to local and systemic infections in communitarian and hospitalised patients. Staphylococcus colonizing nasal or pharyngeal sites can become virulent and cause severe infections.
Publikováno v:
Molecular Medicine Reports
The aim of the present study was to investigate the associations between adiponectin receptor 2 (AdipoR2) gene polymorphisms, AdipoR2 protein expression levels and the risk of colorectal cancer (CRC). From April 2012 to May 2015, 281 CRC patients (ca
Publikováno v:
Molecular Medicine Reports
Osteonecrosis of the femoral head (ONFH) is a multifactorial disease and is associated with genetic predisposition, and exposure to certain risk factors. In particular, idiopathic ONFH in twins and the clustering of cases in families have indicated t
Autor:
Yunfang Ma, Rui Wang, Xiaoyu Pei, Jie Liu, Xiaojiao Zhang, Lijun Wu, Heping Hu, Linqi Chen, Yanyun Ma, Jiucun Wang, Shicheng Guo, Jun Zhang, Siran Liu
Publikováno v:
Molecular Medicine Reports. 10:2736-2744
Polymorphisms in pre‑microRNAs (miRNAs) or mature miRNAs may influence miRNA processing or target binding, thus contributing to tumorigenesis and cancer development. The present study aimed to evaluate whether miR‑149 rs2292832 (C>T) and miR‑60
Autor:
Masakatsu Nakamura, Tomoyuki Shibata, Tomiyasu Arisawa, Hisakazu Shiroeda, Toshimi Otsuka, Natsuko Kawada, Kazuhiro Matsunaga, Tomomitsu Tahara, Takeo Shimasaki, Nobuyuki Toshikuni
Publikováno v:
Molecular Medicine Reports. 9:28-32
Toll-like receptor activation intitially recruits the myeloid differentiation primary response gene (88) (MyD88) protein. A polymorphism *1244 A>G (rs7744) in the 3'-untranslated region of MyD88 has been identified. In the present study, the associat
Autor:
Dong-Mei Meng, Yu-Jiao Zhou, Jiajun Zhao, Lingling Cui, Lin Han, Zheng-Hai Qu, Changgui Li, Luan Wang, Wei Ren
Publikováno v:
Molecular Medicine Reports. 7:1761-1766
The aim of the present study was to investigate the association between genetic variants in 17 tagSNPs of the NLRP3 gene and the susceptibility to primary gouty arthritis. A genotype-phenotype analysis of 480 primary gout and 480 control patients was
Publikováno v:
Molecular medicine reports. 16(1)
Studies on the etiology of essential hypertension (EH) have demonstrated that chronic inflammation contributes to the onset and development of elevated blood pressure. Toll‑like receptors (TLRs), important immune receptors, serve a role in chronic
Autor:
Tomohiko Kawamura, Masaaki Okubo, Ichiro Hirata, Tomiyasu Arisawa, Yoshihito Nakagawa, Tomoyuki Shibata, Hiromi Yamashita, Masakatsu Nakamura, Takamitsu Ishizuka, Tomomitsu Tahara, Naoki Ohmiya, Mitsuo Nagasaka
Publikováno v:
Molecular medicine reports. 11(5)
Interleukin (IL)‑1β, and tumor necrosis factor (TNF)‑α have significant roles in the mediation of inflammatory immune responses and are also potent inhibitors of gastric acid secretion in the stomach. The present study aimed to investigate the
Autor:
X.M. Li, Yi Tong Ma, Zi-Xiang Yu, Bang Dang Chen, Fen Liu, Yi Ning Yang, Xiang Ma, Xiang Xie, Jun‑Yi Luo
Publikováno v:
Molecular medicine reports. 10(3)
Intercellular adhesion molecule‑1 (ICAM‑1) is an important adhesion molecule that has a crucial role in lymphocyte migration and atherosclerosis pathogenesis activation. The aim of the present study was to explore the association between the rs54
Genetic association analysis of CIITA variations with nasal polyp pathogenesis in asthmatic patients
Autor:
Choon-Sik Park, Byung Lae Park, Joon Seol Bae, Jeong Hyun Kim, Hyoung Doo Shin, Hyun Sub Cheong, Soo-Taek Uh, Charisse Flerida A. Pasaje
Publikováno v:
Molecular medicine reports. 7(3)
Nasal polyps are abnormal lesions arising mainly from the nasal mucosa and paranasal sinuses. Since the human class II, major histocompatibility complex, transactivator (CIITA) is a positive regulator of class II, major histocompatibility complex gen