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Publikováno v:
Molecular Medicine Reports
Histone deacetylase 9 (HDAC9) is involved in a variety of malignant tumors, and leads to malignant tumor development and poor prognosis. However, the association between HDAC9 expression, and the prognosis and clinicopathological features of patients
Publikováno v:
Molecular Medicine Reports
Gastric cancer is one of the most common cancers and the second leading cause of cancer‑associated mortality worldwide. Recurrence, metastasis and resistance to drug treatment are the main barrier to survival of patients with advanced stage gastric
Publikováno v:
Molecular Medicine Reports. 16:1479-1485
As one of the first-established negative feedback regulators of angiogenesis, mesenchymal vasohibin-1 (VASH1) serves important roles in the progression and prognosis of various types of tumor. However, the clinical implications of VASH1 in esophageal
Autor:
Yang Gao, Chao‑Jun Duan, Rong Li, Yuan‑Da Cheng, Chun‑Fang Zhang, Zhi‑Wei He, Jun‑Xian Zeng, Yan‑Wu Zhou
Publikováno v:
Molecular Medicine Reports
C14orf166, a 28 kD protein regulating RNA transcription and translation, may serve a critical role in oncogenesis. The aim of the current study was to explore the association between C14orf166 expression and esophageal squamous cell carcinoma (ESCC)
Publikováno v:
Molecular Medicine Reports
The function of runt‑related transcription factor 3 (RUNX3) in oral cancer remains controversial. The present study aimed to determine the status of RUNX3 protein expression and its association with clinicopathological characteristics in tongue squ
Autor:
Wei Wang, Gang Chen, Yong-Yao Gu, Chun-Yao Li, Qianping Zhou, Lanshan Huang, Hui-Ping Lu, Zhen-Bo Feng, Zhi-Gang Peng
Publikováno v:
Molecular Medicine Reports.
Ubiquitin‑specific‑processing protease 34 (USP34) is a deubiquitinase that is involved in the pathogenesis of various cancers. Its roles in diffuse large B‑cell lymphoma (DLBCL) are unknown. The present study aimed to determine the level of USP
Publikováno v:
Molecular Medicine Reports.
Interleukin‑12 receptor (IL‑12R) and p38 mitogen‑activated protein kinase (p38MAPK) serve an important role in non‑small cell lung cancer (NSCLC). It has previously been suggested that IL‑12Rβ2 may be involved in key regulatory pathways an
Autor:
Shuiqing Wu, Yinhuai Wang, Zhaohui Zhong, Ran Xu, Fen Jiang, Qiong Lu, Jian Cao, Xuan Zhu, Hongtao Wu, Xiaokun Zhao
Publikováno v:
Molecular Medicine Reports.
The prognostic significance of hypoxia inducible factor-1α (HIF-1α) expression in tumors and the levels of preoperative hemoglobin in clear cell renal cell carcinoma (ccRCC), with or without concomitant chronic obstructive pulmonary disease (COPD),
Autor:
Yunwei Han, Lijian Xia, Xiaoqian Zhao, Mingyu Yang, Bo Liu, Jingbo Chen, Tiejun Liang, Xiangpeng Xi, Xiaolin Xu
Publikováno v:
Molecular Medicine Reports. 11:1181-1187
Nemo‑like kinase (NLK), a serine/threonine protein kinase, was previously reported to be associated with tumor proliferation and invasion. The present study aimed to evaluate whether NLK participates in the tumorigenesis and progression of colorect
Publikováno v:
Molecular Medicine Reports. 6:779-782
To examine the pathological features and prognosis of different molecular subtypes of breast cancer, the clinical data of 892 breast cancer patients were retrospectively analyzed and divided into four subtypes according to hormone receptor expression