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Publikováno v:
Molecular Medicine Reports
The aim of the present study was to investigate the prognostic significance of the expression of transcription factors, c-Fos, c-Jun and transmembrane protein CD147, in urothelial carcinoma of the bladder (UCB). The current study investigated the cli
Autor:
Dan Shen, Yuanyuan Zeng, Yanbin Chen, Zeyi Liu, Jian-An Huang, Weiwei Ning, Nan Zhang, Jianjie Zhu, Wenwen Du
Publikováno v:
Molecular Medicine Reports
Single nucleotide polymorphisms (SNPs) in microRNA‑binding sites located in the 3'‑untranslated region (UTR) of target genes can have an effect on the interaction of microRNA‑mediated regulation, which results in changes in the expression level
Autor:
Atsushi Wada, Makiko Tanaka, Ryota Masuda, Hiroshi Kijima, Sadaki Inokuchi, Masayuki Iwazaki, Daisuke Masuda, Yoichiro Ikoma, Tomohiko Matsuzaki, Madoka Nito, Kenei Nakazato, Hiroyuki Kobayashi
Publikováno v:
Molecular Medicine Reports
Pathological stage is the most important prognostic factor in patients with lung cancer, and is defined according to the tumor node metastasis classification system. The present study aimed to investigate the clinicopathological significance of lymph
Publikováno v:
Molecular Medicine Reports
Loss of large tumor suppressor kinase 1 (LATS1)Y has been implicated in numerous types of human cancer. However, its involvement in human cervical cancer remains to be elucidated. The present study aimed to investigate the clinical significance and b
Publikováno v:
Molecular Medicine Reports. 16:2281-2289
MicroRNAs (miRNAs) are a group of non-protein‑coding, short single-stranded RNAs, which are considered as promising molecular markers and therapeutic targets in several cancers. The present study explored the expression patterns and functional role
Publikováno v:
Molecular Medicine Reports
The silent information regulator 2 related enzyme 2 (SIRT2) has been reported to have an important role in tumorigenesis. Although two distinct effects of SIRT2 have recently been revealed, which explain opposing expression patterns in different type
Autor:
Meilin Zhang, Baisheng Pan, Wei Guo, Haiying Ji, Jiong Wu, Beili Wang, Fei Huang, Ying Zhao, Shenchao Wu, Chunyan Zhang, Qian Yu, Xin Zhang
Publikováno v:
Molecular Medicine Reports
To explore the possible diagnostic value of liquid biopsy, two multiplex panels using picoliter-droplet digital polymerase chain reaction (ddPCR) were established to quantitatively assess the epidermal growth factor receptor (EGFR) mutations in cell
Publikováno v:
Molecular Medicine Reports. 16:2113-2120
Lung cancer is the primary cause of cancer‑associated mortality in men and women worldwide. Increasing evidence indicates that abnormal microRNA (miRNA) expression contributes to the carcinogenesis and progression of multiple human cancers, includi
Autor:
Aiqin Gao, Xiaosun Guo, Han Chen, Wenli Lin, Wei Gao, Yuping Sun, Qi Dang, Dong Yang, Juan Li, Jie Liu, Xiaoqing Li, Linlin Wang, Pei Zhang
Publikováno v:
Molecular Medicine Reports
Podoplanin and fibroblast growth factor (FGF) 1 have been detected more frequently in lung squamous cell carcinoma (SQCC) compared with lung adenocarcinoma. Furthermore, it has been previous demonstrated that FGF1 is located on the edge of tumor nest
Publikováno v:
Molecular Medicine Reports. 16:325-330
X-linked inhibitor of apoptosis‑associated factor 1 (XAF1) was identified as a novel X-linked inhibitor of apoptosis (XIAP) binding partner that may reverse the anti‑apoptotic effect of XIAP. Previous studies have revealed that XAF1 serves an imp