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Publikováno v:
Molecular Medicine Reports
Girdin is an actin-binding Akt substrate that is involved in the regulation of cell migration. Accumulating evidence has revealed that girdin has regulatory effects on invasion and metastasis in several types of cancer. However, the role of girdin in
Publikováno v:
Molecular Medicine Reports. 16:9741-9748
Atherosclerosis (AS) is an age‑related inflammatory disease. Globule‑epidermal growth factor‑8 (MFG‑E8) and transforming growth factor-β1 (TGF‑β1) are involved in the pathogenesis of AS. However, age‑related changes in circulating level
Autor:
Dan Bing, Yanbo Sun, Yanling Tao, Qingguo Chen, Liangqiang Zhou, Zhihui Du, Zhaogen Cai, Hanqi Chu, Jin Chen, Yun Liu, Chunchen Pan, Ting Tong
Publikováno v:
Molecular Medicine Reports. 16:4934-4940
Previous studies have demonstrated that elevated yes‑associated protein (YAP) expression is associated with tumor aggression and poor prognosis in various types of human cancer. However, the clinicopathological significance and the prognostic value
Autor:
Jing Quan, Xiang Pan, Yongqing Lai, Shangqi Yang, Yun Chen, Xiangming Mao, Jia Hu, Lu Jin, Yifan Li, Yaoting Gui, Tao He
Publikováno v:
Molecular Medicine Reports. 16:7072-7079
Renal cell carcinoma (RCC) is the most common type of kidney cancer and the prognosis of metastatic RCC remains poor, with a high rate of recurrence and mortality. Long non‑coding RNA (lncRNA) is a class of RNA which serves important roles in multi
Autor:
Ilda Patrícia Ribeiro, Isabel M. Carreira, Francisco Batel Marques, Joana B. Melo, Leonor Barroso, Joana Rodrigues, Francisco Caramelo
Publikováno v:
Molecular Medicine Reports
Oral leukoplakia and erythroleukoplakia are common oral potentially malignant disorders diagnosed in the oral cavity. The specific outcome of these lesions remains to be elucidated, as their malignant transformation rate exhibits great variation. The
Publikováno v:
Molecular Medicine Reports
Numerous esophageal squamous cell carcinoma (ESCC) patients exhibit tumor recurrence following radical resection. Invasion and metastasis are key factors in poor prognosis following esophagectomy. In the present study, two‑dimensional gel electroph
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the clinical significance of histone methylation in sepsis. A total of 43 blood samples from trauma and esophageal cancer patients with or without sepsis were collected. Immunofluorescence staining of isolated p
Publikováno v:
Molecular Medicine Reports
The present study aimed specifically investigate the expression and correlation of kelch-like ECH-associated protein‑1 (KEAP1), nuclear factor (erythroid-derived 2)‑like 2 (NRF2), quinone oxidoreductase‑1 (NQO‑1) and heme oxygenase‑1 (HO‑
Autor:
Song Jiang, Ziru Liu, Qiong Zou, Jinghe Li, Zhulin Yang, Lufeng Liang, Yuan Yuan, Senlin Chen, Daiqiang Li, Meigui Chen
Publikováno v:
Molecular Medicine Reports
The clinicopathological and biological characteristics of squamous cell/adenosquamous carcinoma (SC/ASC) of the gallbladder remain to be fully elucidated, due to the fact that it is a rare gallbladder cancer subtype. In the current study, the express
Autor:
Yasuteru Muragaki, Itaru Tojyo, Shigeyuki Fujita, Shin-ichi Murata, Fuyuki Sato, Ujjal K. Bhawal
Publikováno v:
Molecular Medicine Reports.
Basaloid squamous cell carcinomas (BSCCs) in oral lesions are extremely rare, and the histology is not well understood. Histologically, they are often similar to conventional squamous cell carcinoma (SCC). The present study was designed with an aim t