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Autor:
Xiaohong Xue, Pei Lu, Wenjing Diao, Yuankui Cao, Jun Li, Hua Feng, Caiying Zhu, Yu Song, Qisang Guo
Publikováno v:
Molecular Medicine Reports
Tripartite motif‑containing (TRIM) 14 is a protein of the TRIM family. Studies have indicated that TRIM14 may be used as an oncogene in tumor cells, such as osteosarcoma, non‑small cell lung cancer and breast cancer through different pathways. Ho
Publikováno v:
Molecular Medicine Reports
Treatment of human estrogen receptor (ER)-positive breast cancer (ER+ BC) using conventional chemotherapy remains a challenge and is often ineffective as a result of tumor metastasis. The present study aimed to investigate the ability of narasin, an
Publikováno v:
Molecular Medicine Reports
The present study explored whether bone morphogenetic proteins (BMPs) and Wnt/β-catenin signaling pathways were involved in the 1,25(OH)2D3-induced inhibition of osteogenic differentiation in bone marrow-derived mesenchymal stem cells (BMSCs). To ev
Autor:
Lirong Xu, Xiaoli Xu, Zhixiao Lin, Nan Pang, Xueyong Li, Rong Huang, Xiaolin Wang, Xingxing Li, Jinqing Li
Publikováno v:
Molecular Medicine Reports
Wound healing is a complex physiological process in which fibrocytes serve a vital role. However, the mechanism underlying the recruitment of fibrocytes during wound healing remains largely unknown. The present study aimed to investigate whether endo
Autor:
Hui Lv, Yi Gao, Yi‑Xin Du, Qian Liu, Marion Schneider, Sheng‑Sheng Liu, Lei Ye, Zi‑Jian Song, Song‑Guo Li, Wei‑Dong Du, Jian Hong
Publikováno v:
Molecular Medicine Reports
Hemophagocytic lymphohistiocytosis (HLH) is a rare but severe disease characterized by immune hyperactivation and cytokine storm. Given the high mortality rate of HLH, there is a need for more effective diagnostic tools and treatments. The present st
Autor:
Yingran Liang, Xi Chu, Xue Han, Jinghan Li, Jing Shi, Yonggang Gao, Bin Zheng, Li Chu, Zhifeng Zhao, Jianping Zhang
Publikováno v:
Molecular Medicine Reports
Arsenic trioxide (ATO) is commonly used to treat patients with acute promyelocytic leukemia since it was authorized by the U.S. Food and Drug Administration in the 1970s, but its applicability has been limited by its cardiotoxic effects. Therefore, t
Publikováno v:
Molecular Medicine Reports
MicroRNAs (miRs) can affect the progression of cervical cancer (CC). The present study investigated the function of miR‑145‑5p in CC and demonstrated its association with fascin (FSCN1). The expression levels of miR‑145‑5p in CC tissues and c
Autor:
Xindong He, Yongqiang Dong
Publikováno v:
Molecular Medicine Reports
Ankylosis progressive homolog (ANKH) is associated with fibroblast ossification in ankylosing spondylitis (AS). As the human ANKH gene is poorly characterized relative to its murine counterpart, the aim of the present study was to examine ANKH expres
Publikováno v:
Molecular Medicine Reports
The present study aimed to explore the biological functions and molecular mechanisms of the long non‑coding RNA VIM antisense RNA 1 (VIM‑AS1) in gastric cancer (GC). The expression of VIM‑AS1 was analyzed in tissues from patients with GC and GC
Publikováno v:
Molecular Medicine Reports
Severe invasive aspergillosis infection occurs when human immune function is impaired. The interaction between Aspergillus fumigatus (A. fumigatus) conidia and type II lung epithelial cells serves an important role in disease progression. The present