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Autor:
Hui Lv, Yi Gao, Yi‑Xin Du, Qian Liu, Marion Schneider, Sheng‑Sheng Liu, Lei Ye, Zi‑Jian Song, Song‑Guo Li, Wei‑Dong Du, Jian Hong
Publikováno v:
Molecular Medicine Reports
Hemophagocytic lymphohistiocytosis (HLH) is a rare but severe disease characterized by immune hyperactivation and cytokine storm. Given the high mortality rate of HLH, there is a need for more effective diagnostic tools and treatments. The present st
Publikováno v:
Molecular Medicine Reports
The prognosis of advanced non‑small cell lung cancer (NSCLC) is poor; therefore, identifying novel treatment strategies for patients with NSCLC is important. The present study aimed to investigate the efficacy of apatinib plus docetaxel vs. docetax
Publikováno v:
Molecular Medicine Reports
Cataract is a blinding‑caused disease and affects millions of individuals worldwide. Although conventional phacoemulsification (CPCS) has been widely used for treatment of cataract, the incidence of cataract‑caused blindness still increased year
Publikováno v:
Molecular Medicine Reports
The purpose of the present study was to explore the potential molecular signaling pathway mediated by the statin rosuvastatin in cultured human coronary artery endothelial cells (HCAECs) induced by CoCl2. CoCl2 was used to induce the apoptosis of HCA
Publikováno v:
Molecular Medicine Reports
Familial glucocorticoid deficiency (FGD) is a rare autosomal recessive disease characterized by single cortisol deficiency but normal aldosterone and renin levels. Beginning from the discovery of the disease to that of the pathogenic genes over a per
Publikováno v:
Molecular Medicine Reports
Diabetic cardiomyopathy (DCM) is a serious complication of diabetes, which importantly contributes to the increased mortality of patients with diabetes. The development of DCM is accompanied by numerous pathological mechanisms, including oxidative st
Publikováno v:
Molecular Medicine Reports
Melatonin (MT) is an indoleamine hormone that can counteract ischemia‑induced organ injury through its antioxidant effects. The aim of the present study was to investigate the protective effects of exogenous MT against hemorrhagic shock (HS)‑indu
Autor:
Hongwei Wang, Yi-Ling Feng, Yi-Hong Wang, Minmin Wu, Ming-Shi Zhou, Li-Jun Kong, Hua-Chun Weng, Cheng-Yang Liu, Yuan-Cai Zheng
Publikováno v:
Molecular Medicine Reports
Islet transplantation (IT) is considered the most effective endocrine replacement therapy for diabetes mellitus (DM). Studies have demonstrated that IT can repair testicular structural injury caused by inflammatory and oxidative stress in a diabetic
Publikováno v:
Molecular Medicine Reports
Nucleotide‑binding oligomerization domain, leucine rich repeat, and pyrin domain‑containing protein 3 (NLRP3) inflammasome has been implicated in a series of physiological and pathological processes. However, its correlation in coronary heart dis
Publikováno v:
Molecular Medicine Reports
The progression of disease caused by fungal infection is closely associated with the human immune system. Macrophages and natural killer cells (NK cells) are two important types of innate immune cells that serve an important role in anti‑infection