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Publikováno v:
Molecular Medicine Reports
Circular RNAs (circRNAs) serve important roles in tumorigenesis and may be used as novel molecular biomarkers for clinical diagnosis. However, the role and molecular mechanisms of circRNAs in cervical cancer (CC) remain unknown. In the present study,
Autor:
Zhiwei Hu, Dingyun Li, Yafei Ling, Ting Wang, Tao Zhang, Shengquan He, Jiajun Lai, Jian Zhang
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the function of microRNA‑25 (miR‑25) in human colon cancer cell viability and migration in addition to the underlying possible mechanisms. miR‑25 expression was upregulated in patients with colon cancer co
Publikováno v:
Molecular Medicine Reports
Nasopharyngeal carcinoma (NPC) is a type of cancer originating in the nasopharynx. There are no NPC‑specific treatments available at present. Serpin peptidase inhibitor clade C member 1 (SERPINC1) serves roles in anticoagulation and anti‑inflamma
Publikováno v:
Molecular Medicine Reports
The present study aimed to investigate the expression of microRNA (miR)-133a in patients with or without acute myocardial infarction (AMI) following radical surgery for gastric cancer, and to explore its underlying mechanisms. Blood samples were coll
Publikováno v:
Molecular Medicine Reports
MicroRNA (miR)‑200b‑3p is downregulated in multiple human cancer types. Wnt signaling serves a role in human colorectal cancer (CRC). The present study aimed to examine the effect of miR‑200b‑3p on human CRC and its potential association with
Autor:
Huaizhi Wang, Yongsheng Ouyang, Yunchao Wang, Jiali Yang, Liangyu Yin, Xuejun Xu, Shixiang Guo, Jiayun Ge
Publikováno v:
Molecular Medicine Reports
Pancreatic cancer remains one of the most malignant tumors with a poor prognosis. Despite advances in diagnosis and treatment, no reliable biomarkers are available for clinical practice. Circular RNAs (circRNAs) are a novel class of endogenous non‑
Publikováno v:
Molecular Medicine Reports
Dysregulation of micro (mi)RNA-let-7 has been associated with the development and prognosis of multiple cancer types. Lin28, a RNA-binding protein, plays a conserved role in regulating the maturation of let-7 family proteins. However, few studies hav
Autor:
Zhi‑Hua Ye, Ding‑Wen Gui
Publikováno v:
Molecular Medicine Reports
Renal cell carcinoma (RCC) is one of the most common urinary malignancies with a high rate of morbidity. MicroRNAs (miRNAs) have been shown to be critical post‑transcriptional regulators in tumorigenesis. The present study aimed to investigate the
Publikováno v:
Molecular Medicine Reports. 16:9143-9148
Gastric cancer (GC) is one of the major leading causes of cancer‑associated mortality worldwide. Serum biomarkers have a vital role in diagnosis and prognosis of GC, and interleukin (IL)‑16 may serve as a useful biomarker with prognostic value fo
Publikováno v:
Molecular Medicine Reports
CDGSH iron sulfur domain 2 (CISD2) has been found to be important in carcinogenesis. However, the role of CISD2 in glioma remains to be elucidated. The present study aimed to investigate the role of CISD2 in glioma using the reverse transcription‑q