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Autor:
Zhendong Liu, Yanbiao Wang, Yanzheng Gao, Yongjie Zhu, Xingbo Cheng, Zhibin Han, Yaoye Zhao, Binfeng Liu, Runze Liu, Xiaoyu Lian
Publikováno v:
Molecular Medicine, Vol 27, Iss 1, Pp 1-17 (2021)
Background GINS4, an indispensable component of the GINS complex, is vital for a variety of cancer. However, no known empirical research has focused on exploring relationships between GINS4 and glioma. Thus, this study aims to understand and explain
Publikováno v:
Molecular Medicine, Vol 26, Iss 1, Pp 1-9 (2020)
Molecular Medicine
Molecular Medicine
Introduction Targeted therapy for NSCLC is rapidly evolving. EGFR-TKIs benefit NSCLC patients with sensitive EGFR mutations and significantly prolong survival. However, 20–30% of patients demonstrate primary resistance to EGFR-TKIs, which leads to
Autor:
Alberto Ballestrero, Manlio Ferrarini, Anna Truini, Giannamaria Cerruti, Carlotta Massucco, Gabriele Zoppoli, Silvana Chiara, C. Sonaglio, Simona Zupo, Mariella Dono, Mauro Truini, Marco Mora
Publikováno v:
Scopus-Elsevier
Metastatic colorectal cancer (mCRC) is frequently characterized by the presence of mutations of the KRAS oncogene, which are generally associated with a poor response to treatment with anti-epidermal growth factor receptor (anti-EGFR) monoclonal anti