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Autor:
Terry F. Davies, P. Graves
Publikováno v:
Molecular Endocrinology. 4:155-161
A 0.95-kilobase (kb) thyrocyte RNA, initially detected in our 1B-6 subclone of Fisher rat thyrocytes (FRTL-5) using an oligonucleotide probe complementary to the 5' end of rat thyroglobulin (Tg) mRNA, was also detected in cultured thyrocytes of the W
Publikováno v:
Molecular Endocrinology. 23:1936-1936
Background We recently reported on the effects of exogenous growth differentiation factor 9 (GDF9) in enhancing activin A-induced inhibin βB-subunit mRNA and inhibin B levels in human granulosa-lutein (hGL) cells by modulating key components of the
Autor:
Lisa H. Fish, W B Kinlaw, Harold L. Schwartz, Ana Perez-Castillo, Cary N. Mariash, Jack H. Oppenheimer
Publikováno v:
Molecular Endocrinology. 1:609-613
The mRNA of the rat hepatic S14 gene accumulates rapidly after administration of T3 and carbohydrate, making it an excellent model for studies of the effects of dietary and hormonal stimuli at the hepatocellular level. We undertook studies to assess
Publikováno v:
Molecular Endocrinology. 2:528-535
Alternative splicing of insulin-like growth factor I (IGF-I)/somatomedin C mRNAs generates two IGF-I mRNAs coding for IGF-I peptides with different sequences in the E domain of the IGF-I prohormone. These two mRNAs encode alternative E peptides due t
Autor:
Christina A. Harrington, Mindy F. Rosenthal, Dona M. Chikaraishi, Joan I. Morrell, Joseph T. McCabe, Donald W. Pfaff
Publikováno v:
Molecular Endocrinology. 3:1426-1433
The dopamine-producing neurons of the tuberoinfundibular region are known targets of estrogen and progesterone, and are of considerable neuroendocrine importance. To determine the anatomical distribution, and number of cells that contain tyrosine hyd
Publikováno v:
Molecular Endocrinology. 3:976-983
We have previously reported the immunohistochemical localization of transforming growth factor-alpha (TGF alpha) in the intact bovine anterior pituitary gland. Furthermore, we have purified TGF alpha from the conditioned medium of cell cultures deriv
Publikováno v:
Molecular Endocrinology. 3:1132-1141
In two cellular models of insulin resistance we measured glucose transport activity, total glucose transporter number using the cytochalasin B binding assay, and expression of a transporter mRNA species specifically hybridizing with cDNA cloned from
Publikováno v:
Molecular Endocrinology. 3:295-304
Since sex steroid hormones and growth factors are known to modulate the proliferation of breast tumors, we have studied the effects of estrogen and progestin, their antagonists, and growth factors on the regulation of estrogen receptor (ER) mRNA and
Publikováno v:
Molecular Endocrinology. 3:887-894
The inhibitory effects of recombinant porcine interferon-gamma (IFN gamma) on human CG (hCG)-stimulated testosterone production, and on mRNA concentrations of cholesterol side-chain cleavage (P450scc) and 17 alpha-hydroxylase/C17-20lyase (P450c 17) w
Publikováno v:
Molecular Endocrinology. 2:1256-1264
The mechanism of ligand-induced (homologous) down-regulation of the glucocorticoid receptor (GR) has been studied. Dexamethasone caused a down-regulation of the levels of GR mRNA and protein both in hepatoma tissue culture cells and rat liver in vivo