Zobrazeno 1 - 9
of 9
pro vyhledávání: ''
Autor:
Sophie Giorgetti-Peraldi, Marie-Noëlle Monthouël-Kartmann, Joseph Murdaca, Emmanuel Van Obberghen, Caroline Treins
Publikováno v:
Molecular Endocrinology. 19:1304-1317
Hypoxia-inducible factor-1 (HIF-1), a transcription factor composed of two subunits (HIF-1alpha and HIF-1beta), initially described as a mediator of adaptive responses to changes in tissue oxygenation, has been shown to be activated in an oxygen-inde
Publikováno v:
Molecular Endocrinology. 18:1670-1686
Previous studies have shown that the synthesis and stability of milk protein mRNAs are regulated by lactogenic hormones. We demonstrate here in cultured mouse mammary epithelial cells (CID 9) that insulin plus prolactin also synergistically increases
Publikováno v:
Molecular Endocrinology. 12:568-579
Steroidal (ICI 182, 780) and nonsteroidal hydroxytamoxifen (OH-Tam) antiestrogens inhibit growth factor-mitogenic activity in MCF 7 estrogen receptor-positive human breast cancer cells. Cell inhibition is correlated with an increase in membrane prote
Publikováno v:
Molecular Endocrinology. 11:997-1007
The growth-promoting activity of GH, the principal hormonal determinant of body size, is mediated by insulin-like growth factor I (IGF-I). Most of the IGF-I in plasma circulates in a 150-kDa complex that contains IGF-binding protein-3 (IGFBP-3) and a
Publikováno v:
Molecular Endocrinology. 8:794-805
Insulin-like growth factor-binding protein-1 (IGFBP-1) modulates the action of IGFs on target cells. IGFBP-1 transcription is highly regulated by hormonal and metabolic factors. In rat H4-II-E hepatoma cells, IGFBP-1 messenger RNA is stimulated by de
Publikováno v:
Molecular Endocrinology. 7:380-386
The insulin-like growth factors (IGFs) are potent mitogens with both endocrine and autocrine-paracrine effects on cell growth. The IGF binding proteins (IGFBPs) are found in many human biological fluids and in the conditioned media of many cell cultu
Autor:
Michael R. Stallcup, Janis L. Corey
Publikováno v:
Molecular Endocrinology. 6:450-458
Mouse lymphoma cell line W7MG1 is stably infected with mouse mammary tumor virus and produces the viral envelope glycoprotein precursor Pr74, but the mature envelope proteins gp52 and gp33, which are derived from Pr74 by posttranslational processing,
Autor:
J. Schwander, Christoph Schmid, Ernst Rudolf Prof Dr Froesch, J Zapf, Peter J. Meier, J.-L. Mary, M. Boni-Schnetzler, B. Zimmerli
Publikováno v:
Molecular Endocrinology. 4:1320-1326
The goal of this study was to find out whether GH or insulin regulate the mRNA expression of the fetal binding protein of insulin-like growth factor (IGFBP-2). Primary hepatocytes from adult rats were used as a test system. IGFBP-2 mRNA was abundant
Publikováno v:
Molecular Endocrinology. 4:1199-1204
The low mol wt insulin-like growth factor-binding protein (IGFBP-1) originally isolated from amniotic fluid has been considered to be GH independent. In this report we have examined the effect of GH on hepatic IGFBP-1 expression in the hypophysectomi