Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kathy Mulgrew"'
Autor:
Nicholas M. Durham, Ruth Franks, Christel Navarro, Kelly McGlinchey, Hong Jin, Nicola Rath, Robert W. Wilkinson, James Harper, Andrew Leinster, Rebecca Leyland, Xing Cheng, Simon J. Dovedi, Kathy Mulgrew, Lee Brown, Jon Travers, Jens-Oliver Koopmann, Shannon Burke, Danielle Carroll, Jim Eyles
Publikováno v:
Molecular Cancer Therapeutics. 20:1723-1734
A recombinant Newcastle Disease Virus (NDV), encoding either a human (NDVhuGM-CSF, MEDI5395) or murine (NDVmuGM-CSF) GM-CSF transgene, combined broad oncolytic activity with the ability to significantly modulate genes related to immune functionality
Autor:
Andrew W. Sylwester, James Hair, Scott A. Hammond, Qun Du, Nicholas Buss, Lolke de Haan, Michael Oberst, Kathy Mulgrew, Louis J. Picker, Michael K. Axthelm, Melissa Damschroder, Hui Feng, Andrew D. Weinberg, Haesun Park, Shino Hanabuchi, Steven Eck, Stacy R. Kentner, Chad Morris, Kelly McGlinchey, Nicholas P. Morris, Andrew J. Pierce, Catherine Auge
Publikováno v:
Molecular Cancer Therapeutics. 17:1024-1038
Ligation of OX40 (CD134, TNFRSF4) on activated T cells by its natural ligand (OX40L, CD252, TNFSF4) enhances cellular survival, proliferation, and effector functions such as cytokine release and cellular cytotoxicity. We engineered a recombinant huma
Autor:
Xiao Tao Yao, Bill Walsh, Michael S. Kinch, Krista Kinneer, Kathy Mulgrew, David A. Tice, Changshou Gao, Beth K. Ward, Peter A. Kiener, Steve Coats, Su Yau Mao, Melissa Damschroder
Publikováno v:
Molecular Cancer Therapeutics. 5:3122-3129
The humanized monoclonal antibody Abegrin™, currently in phase II trials for treatment of solid tumors, specifically recognizes the integrin αvβ3. Due to its high expression on mature osteoclasts, angiogenic endothelial cells, and tumor cells, in