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pro vyhledávání: '"Colin P.N. Dinney"'
Autor:
Maria Simona Pino, Liana Adam, Marissa Shrader, David J. McConkey, Colin P.N. Dinney, Peter McL. Black, Gordon A. Brown, Menahse Bar-Eli
Publikováno v:
Molecular Cancer Therapeutics. 6:277-285
We characterized the effects of the small molecule epidermal growth factor receptor (EGFR) inhibitor gefitinib (ZD1839, Iressa) on cell proliferation in a panel of 17 human bladder cancer cell lines. Gefitinib inhibited DNA synthesis in a concentrati
Autor:
Angela Papageorgiou, Colin P.N. Dinney, David J. McConkey, William F. Benedict, Ashish M. Kamat
Publikováno v:
Molecular cancer therapeutics. 5(12)
In a recent study, we showed that the proteasome inhibitor bortezomib sensitizes human bladder cancer cells to IFN-induced cell death. Here, we characterized the molecular mechanisms underlying the antitumoral effects of the combination in more detai